In silico analysis of TUBA4A mutations in Amyotrophic Lateral Sclerosis to define mechanisms of microtubule disintegration von Ganne, Akshatha, Balasubramaniam, Meenakshisundaram, Ayyadevara, Haarika, Kiaei, Lily, Shmookler Reis, Robert J., Varughese, Kottayil I., Kiaei, Mahmoud

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Structure-based Design Targeted at LOX-1, a Receptor for Oxidized Low-Density Lipoprotein von Thakkar, Shraddha, Wang, Xianwei, Khaidakov, Magomed, Dai, Yao, Gokulan, Kuppan, Mehta, Jawahar L., Varughese, Kottayil I.

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FAM98 Family Proteins Play Distinct Roles in Osteoclastogenesis and Bone Resorption von Wang, Lei, Minocha, Tarun, Das, Bhaba K, Kunika, Mikaela D, Kannan, Aarthi, Gao, Ling, Mohan, Subburaman, Xing, Weirong, Varughese, Kottayil I, Zhao, Haibo

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LOX-1 in Atherosclerosis and Myocardial Ischemia von Pothineni, Naga Venkata K., MD, Karathanasis, Sotirios K., PhD, Ding, Zufeng, PhD, Arulandu, Arockiasamy, PhD, Varughese, Kottayil I., PhD, Mehta, Jawahar L., MD, PhD

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LIS1 Regulates Osteoclastogenesis through Modulation of M-SCF and RANKL Signaling Pathways and CDC42 von Ye, Shiqiao, Fujiwara, Toshifumi, Zhou, Jian, Varughese, Kottayil I, Zhao, Haibo

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LOX-1 in Atherosclerosis and Myocardial Ischemia: Biology, Genetics, and Modulation von Pothineni, Naga Venkata K, Karathanasis, Sotirios K, Ding, Zufeng, Arulandu, Arockiasamy, Varughese, Kottayil I, Mehta, Jawahar L

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Structural characterization of a therapeutic anti-methamphetamine antibody fragment: oligomerization and binding of active metabolites von Peterson, Eric C, Celikel, Reha, Gokulan, Kuppan, Varughese, Kottayil I

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The Crystal Structure of Beryllofluoride Spo0F in Complex with the Phosphotransferase Spo0B Represents a Phosphotransfer Pretransition State von VARUGHESE, Kottayil I, TSIGELNY, Igor, HAIYAN ZHAO

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Correction: Structural Characterization of a Therapeutic Anti-Methamphetamine Antibody Fragment: Oligomerization and Binding of Active Metabolites von Peterson, Eric C., Celikel, Reha, Gokulan, Kuppan, Varughese, Kottayil I.

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Exploring the druggability of oxidized low-density lipoprotein (ox-LDL) receptor, LOX-1, a proatherogenic drug target involved in atherosclerosis von Tomar, Akanksha, Sahoo, Sibasis, Aathi, Muthusankar, Kuila, Shobhan, Khan, Mohd Azeem, Ravi, Guru Raj Rao, Jeyaraman, Jeyakanthan, Mehta, Jawahar L., Varughese, Kottayil I., Arockiasamy, Arulandu

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Drug resistance in Mycobacterium tuberculosis and targeting the l,d‐transpeptidase enzyme von Gokulan, Kuppan, Varughese, Kottayil I.

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A transient interaction between two phosphorelay proteins trapped in a crystal lattice reveals the mechanism of molecular recognition and phosphotransfer in signal transduction von Zapf, James, Sen, Udayaditya, Madhusudan, Hoch, James A, Varughese, Kottayil I

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Crystal structure of the transcriptional repressor PagR of Bacillus anthracis von Zhao, Haiyan, Volkov, Arsen, Veldore, Vidya Harini, Hoch, James A, Varughese, Kottayil I

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The structural basis of effective LOX-1 inhibition von Kore, Rajshekhar A, Bagchi, Ashim K, Varughese, Kottayil I, Mehta, Jawahar L

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(E)-13-(4-Amino-phen-yl)parthenolide von Penthala, Narsimha Reddy, Janganati, Venumadhav, Parkin, Sean, Varughese, Kottayil I, Crooks, Peter A

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ALS-causing mutations in profilin-1 alter its conformational dynamics: A computational approach to explain propensity for aggregation von Kiaei, Mahmoud, Balasubramaniam, Meenakshisundaram, Govind Kumar, Vivek, Shmookler Reis, Robert J., Moradi, Mahmoud, Varughese, Kottayil I.

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Structure and Inhibitor Specificity of L,D-Transpeptidase (LdtMt2) from Mycobacterium tuberculosis and Antibiotic Resistance: Calcium Binding Promotes Dimer Formation von Gokulan, Kuppan, Khare, Sangeeta, Cerniglia, Carl E., Foley, Steven L., Varughese, Kottayil I.

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Molecular and functional mapping of Plekhm1-Rab7 interaction in osteoclasts von Das, Bhaba K, Minocha, Tarun, Kunika, Mikaela D, Kannan, Aarthi, Gao, Ling, Mohan, Subburaman, Xing, Weirong, Varughese, Kottayil I, Zhao, Haibo

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Conformational Changes of Spo0F along the Phosphotransfer Pathway von VARUGHESE, Kottayil I, WEMMER, David E, KERN, Dorothee

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Affinity improvement of a therapeutic antibody to methamphetamine and amphetamine through structure-based antibody engineering von Thakkar, Shraddha, Nanaware-Kharade, Nisha, Celikel, Reha, Peterson, Eric C., Varughese, Kottayil I.

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