Mismatch Repair-Deficient Rectal Cancer and Resistance to Neoadjuvant Chemotherapy von Cercek, Andrea, Dos Santos Fernandes, Gustavo, Roxburgh, Campbell S, Ganesh, Karuna, Ng, Shu, Sanchez-Vega, Francisco, Yaeger, Rona, Segal, Neil H, Reidy-Lagunes, Diane L, Varghese, Anna M, Markowitz, Arnold, Wu, Chao, Szeglin, Bryan, Sauvé, Charles-Etienne Gabriel, Salo-Mullen, Erin, Tran, Christina, Patel, Zalak, Krishnan, Asha, Tkachuk, Kaitlyn, Nash, Garrett M, Guillem, Jose, Paty, Philip B, Shia, Jinru, Schultz, Nikolaus, Garcia-Aguilar, Julio, Diaz, Luis A, Goodman, Karyn, Saltz, Leonard B, Weiser, Martin R, Smith, J Joshua, Stadler, Zsofia K

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Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer von Yaeger, Rona, Chatila, Walid K., Lipsyc, Marla D., Hechtman, Jaclyn F., Cercek, Andrea, Sanchez-Vega, Francisco, Jayakumaran, Gowtham, Middha, Sumit, Zehir, Ahmet, Donoghue, Mark T.A., You, Daoqi, Viale, Agnes, Kemeny, Nancy, Segal, Neil H., Stadler, Zsofia K., Varghese, Anna M., Kundra, Ritika, Gao, Jianjiong, Syed, Aijazuddin, Hyman, David M., Vakiani, Efsevia, Rosen, Neal, Taylor, Barry S., Ladanyi, Marc, Berger, Michael F., Solit, David B., Shia, Jinru, Saltz, Leonard, Schultz, Nikolaus

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Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and Recommendations von Hu, Zishuo I, Shia, Jinru, Stadler, Zsofia K, Varghese, Anna M, Capanu, Marinela, Salo-Mullen, Erin, Lowery, Maeve A, Diaz, Jr, Luis A, Mandelker, Diana, Yu, Kenneth H, Zervoudakis, Alice, Kelsen, David P, Iacobuzio-Donahue, Christine A, Klimstra, David S, Saltz, Leonard B, Sahin, Ibrahim H, O'Reilly, Eileen M

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Ordered and deterministic cancer genome evolution after p53 loss von Baslan, Timour, Morris, John P., Zhao, Zhen, Reyes, Jose, Ho, Yu-Jui, Tsanov, Kaloyan M., Bermeo, Jonathan, Tian, Sha, Zhang, Sean, Askan, Gokce, Yavas, Aslihan, Lecomte, Nicolas, Erakky, Amanda, Varghese, Anna M., Zhang, Amy, Kendall, Jude, Ghiban, Elena, Chorbadjiev, Lubomir, Wu, Jie, Dimitrova, Nevenka, Chadalavada, Kalyani, Nanjangud, Gouri J., Bandlamudi, Chaitanya, Gong, Yixiao, Donoghue, Mark T. A., Socci, Nicholas D., Krasnitz, Alex, Notta, Faiyaz, Leach, Steve D., Iacobuzio-Donahue, Christine A., Lowe, Scott W.

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Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer von Rojas, Luis A., Sethna, Zachary, Soares, Kevin C., Olcese, Cristina, Pang, Nan, Patterson, Erin, Lihm, Jayon, Ceglia, Nicholas, Guasp, Pablo, Chu, Alexander, Yu, Rebecca, Chandra, Adrienne Kaya, Waters, Theresa, Ruan, Jennifer, Amisaki, Masataka, Zebboudj, Abderezak, Odgerel, Zagaa, Payne, George, Derhovanessian, Evelyna, Müller, Felicitas, Rhee, Ina, Yadav, Mahesh, Dobrin, Anton, Sadelain, Michel, Łuksza, Marta, Cohen, Noah, Tang, Laura, Basturk, Olca, Gönen, Mithat, Katz, Seth, Do, Richard Kinh, Epstein, Andrew S., Momtaz, Parisa, Park, Wungki, Sugarman, Ryan, Varghese, Anna M., Won, Elizabeth, Desai, Avni, Wei, Alice C., D’Angelica, Michael I., Kingham, T. Peter, Mellman, Ira, Merghoub, Taha, Wolchok, Jedd D., Sahin, Ugur, Türeci, Özlem, Greenbaum, Benjamin D., Jarnagin, William R., Drebin, Jeffrey, O’Reilly, Eileen M., Balachandran, Vinod P.

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Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer von Latham, Alicia, Srinivasan, Preethi, Kemel, Yelena, Shia, Jinru, Bandlamudi, Chaitanya, Mandelker, Diana, Middha, Sumit, Hechtman, Jaclyn, Zehir, Ahmet, Dubard-Gault, Marianne, Tran, Christina, Stewart, Carolyn, Sheehan, Margaret, Penson, Alexander, DeLair, Deborah, Yaeger, Rona, Vijai, Joseph, Mukherjee, Semanti, Galle, Jesse, Dickson, Mark A, Janjigian, Yelena, O'Reilly, Eileen M, Segal, Neil, Saltz, Leonard B, Reidy-Lagunes, Diane, Varghese, Anna M, Bajorin, Dean, Carlo, Maria I, Cadoo, Karen, Walsh, Michael F, Weiser, Martin, Aguilar, Julio Garcia, Klimstra, David S, Diaz, Jr, Luis A, Baselga, Jose, Zhang, Liying, Ladanyi, Marc, Hyman, David M, Solit, David B, Robson, Mark E, Taylor, Barry S, Offit, Kenneth, Berger, Michael F, Stadler, Zsofia K

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ALK rearrangements are mutually exclusive with mutations in EGFR or KRAS: an analysis of 1,683 patients with non-small cell lung cancer von Gainor, Justin F, Varghese, Anna M, Ou, Sai-Hong Ignatius, Kabraji, Sheheryar, Awad, Mark M, Katayama, Ryohei, Pawlak, Amanda, Mino-Kenudson, Mari, Yeap, Beow Y, Riely, Gregory J, Iafrate, A John, Arcila, Maria E, Ladanyi, Marc, Engelman, Jeffrey A, Dias-Santagata, Dora, Shaw, Alice T

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First-in-Class ERK1/2 Inhibitor Ulixertinib (BVD-523) in Patients with MAPK Mutant Advanced Solid Tumors: Results of a Phase I Dose-Escalation and Expansion Study von Sullivan, Ryan J, Infante, Jeffrey R, Janku, Filip, Wong, Deborah Jean Lee, Sosman, Jeffrey A, Keedy, Vicki, Patel, Manish R, Shapiro, Geoffrey I, Mier, James W, Tolcher, Anthony W, Wang-Gillam, Andrea, Sznol, Mario, Flaherty, Keith, Buchbinder, Elizabeth, Carvajal, Richard D, Varghese, Anna M, Lacouture, Mario E, Ribas, Antoni, Patel, Sapna P, DeCrescenzo, Gary A, Emery, Caroline M, Groover, Anna L, Saha, Saurabh, Varterasian, Mary, Welsch, Dean J, Hyman, David M, Li, Bob T

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CAR T‐cell therapy for pancreatic cancer von DeSelm, Carl J., Tano, Zachary E., Varghese, Anna M., Adusumilli, Prasad S.

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Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection von Park, Wungki, Chen, Jiapeng, Chou, Joanne F, Varghese, Anna M, Yu, Kenneth H, Wong, Winston, Capanu, Marinela, Balachandran, Vinod, McIntyre, Caitlin A, El Dika, Imane, Khalil, Danny N, Harding, James J, Ghalehsari, Nima, McKinnell, Zoe, Chalasani, Sree B, Makarov, Vladimir, Selenica, Pier, Pei, Xin, Lecomte, Nicolas, Kelsen, David P, Abou-Alfa, Ghassan K, Robson, Mark E, Zhang, Liying, Berger, Michael F, Schultz, Nikolaus, Chan, Timothy A, Powell, Simon N, Reis-Filho, Jorge S, Iacobuzio-Donahue, Christine A, Riaz, Nadeem, O'Reilly, Eileen M

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Nanoliposomal irinotecan with fluorouracil for the treatment of advanced pancreatic cancer, a single institution experience von Glassman, Danielle C, Palmaira, Randze L, Covington, Christina M, Desai, Avni M, Ku, Geoffrey Y, Li, Jia, Harding, James J, Varghese, Anna M, O'Reilly, Eileen M, Yu, Kenneth H

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Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms von Lowery, Maeve A, Wong, Winston, Jordan, Emmet J, Lee, Jonathan W, Kemel, Yelena, Vijai, Joseph, Mandelker, Diana, Zehir, Ahmet, Capanu, Marinela, Salo-Mullen, Erin, Arnold, Angela G, Yu, Kenneth H, Varghese, Anna M, Kelsen, David P, Brenner, Robin, Kaufmann, Erica, Ravichandran, Vignesh, Mukherjee, Semanti, Berger, Michael F, Hyman, David M, Klimstra, David S, Abou-Alfa, Ghassan K, Tjan, Catherine, Covington, Christina, Maynard, Hannah, Allen, Peter J, Askan, Gokce, Leach, Steven D, Iacobuzio-Donahue, Christine A, Robson, Mark E, Offit, Kenneth, Stadler, Zsofia K, O'Reilly, Eileen M

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A First-in-Human Phase 1 Study of LY3023414, an Oral PI3K/mTOR Dual Inhibitor, in Patients with Advanced Cancer von Bendell, Johanna C, Varghese, Anna M, Hyman, David M, Bauer, Todd M, Pant, Shubham, Callies, Sophie, Lin, Ji, Martinez, Ricardo, Wickremsinhe, Enaksha, Fink, Aaron, Wacheck, Volker, Moore, Kathleen N

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Reliable Detection of Mismatch Repair Deficiency in Colorectal Cancers Using Mutational Load in Next-Generation Sequencing Panels von Stadler, Zsofia K, Battaglin, Francesca, Middha, Sumit, Hechtman, Jaclyn F, Tran, Christina, Cercek, Andrea, Yaeger, Rona, Segal, Neil H, Varghese, Anna M, Reidy-Lagunes, Diane L, Kemeny, Nancy E, Salo-Mullen, Erin E, Ashraf, Asad, Weiser, Martin R, Garcia-Aguilar, Julio, Robson, Mark E, Offit, Kenneth, Arcila, Maria E, Berger, Michael F, Shia, Jinru, Solit, David B, Saltz, Leonard B

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Genomic profiling in pancreatic ductal adenocarcinoma and a pathway towards therapy individualization: A scoping review von Singh, Ritu R., Goldberg, Johanna, Varghese, Anna M., Yu, Kenneth H., Park, Wungki, O'Reilly, Eileen M.

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Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype von Lowery, Maeve A, Jordan, Emmet J, Basturk, Olca, Ptashkin, Ryan N, Zehir, Ahmet, Berger, Michael F, Leach, Tanisha, Herbst, Brian, Askan, Gokce, Maynard, Hannah, Glassman, Danielle, Covington, Christina, Schultz, Nikolaus, Abou-Alfa, Ghassan K, Harding, James J, Klimstra, David S, Hechtman, Jaclyn F, Hyman, David M, Allen, Peter J, Jarnagin, William R, Balachandran, Vinod P, Varghese, Anna M, Schattner, Mark A, Yu, Kenneth H, Saltz, Leonard B, Solit, David B, Iacobuzio-Donahue, Christine A, Leach, Steven D, O'Reilly, Eileen M

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Clinico-genomic Characterization of ATM and HRD in Pancreas Cancer: Application for Practice von Park, Wungki, O'Connor, Catherine A, Bandlamudi, Chaitanya, Forman, Daniella, Chou, Joanne F, Umeda, Shigeaki, Reyngold, Marsha, Varghese, Anna M, Keane, Fergus, Balogun, Fiyinfolu, Yu, Kenneth H, Kelsen, David P, Crane, Christopher, Capanu, Marinela, Iacobuzio-Donahue, Christine, O'Reilly, Eileen M

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Early-Onset Pancreas Cancer: Clinical Descriptors, Genomics, and Outcomes von Varghese, Anna M, Singh, Isha, Singh, Rituraj, Kunte, Siddharth, Chou, Joanne F, Capanu, Marinela, Wong, Winston, Lowery, Maeve A, Stadler, Zsofia K, Salo-Mullen, Erin, Saadat, Lily V, Wei, Alice C, Reyngold, Marsha, Basturk, Olca, Benayed, Ryma, Mandelker, Diana, Iacobuzio-Donahue, Christine A, Kelsen, David P, Park, Wungki, Yu, Kenneth H, O'Reilly, Eileen M

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Current management and future directions in metastatic pancreatic adenocarcinoma von Varghese, Anna M., Lowery, Maeve A., Yu, Kenneth H., O'Reilly, Eileen M.

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Safety and activity of the TGFβ receptor I kinase inhibitor galunisertib plus the anti-PD-L1 antibody durvalumab in metastatic pancreatic cancer von Melisi, Davide, Oh, Do-Youn, Hollebecque, Antoine, Calvo, Emiliano, Varghese, Anna, Borazanci, Erkut, Macarulla, Teresa, Merz, Valeria, Zecchetto, Camilla, Zhao, Yumin, Gueorguieva, Ivelina, Man, Michael, Gandhi, Leena, Estrem, Shawn T, Benhadji, Karim A, Lanasa, Mark C, Avsar, Emin, Guba, Susan C, Garcia-Carbonero, Rocio

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