Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1 von Shen, J, Samul, R, Silva, R L, Akiyama, H, Liu, H, Saishin, Y, Hackett, S F, Zinnen, S, Kossen, K, Fosnaugh, K, Vargeese, C, Gomez, A, Bouhana, K, Aitchison, R, Pavco, P, Campochiaro, P A

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WVE-210201, an investigational stereopure oligonucleotide therapy for Duchenne muscular dystrophy, induces Exon 51 skipping and dystrophin protein restoration von Wood, M., Zhang, J., Bowman, K., Butler, D., Rinaldi, C., McClorey, G., Frank-Kamenetsky, M., Iwamoto, N., Kothari, N., Lu, G., Mathieu, S., Meena, M., Menon, S., Shimizu, M., Standley, S., Yang, H., Zhong, Z., Francis, C., Vargeese, C.

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Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs von Morrissey, David V, Lockridge, Jennifer A, Shaw, Lucinda, Blanchard, Karin, Jensen, Kristi, Breen, Wendy, Hartsough, Kimberly, Machemer, Lynn, Radka, Susan, Jadhav, Vasant, Vaish, Narendra, Zinnen, Shawn, Vargeese, Chandra, Bowman, Keith, Shaffer, Chris S, Jeffs, Lloyd B, Judge, Adam, MacLachlan, Ian, Polisky, Barry

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Intimal Hyperplasia Recurs After Removal of PDGF-AB and -BB Inhibition in the Rat Carotid Artery Injury Model von Leppänen, Olli, Janjic, Nebojsa, Carlsson, Mari-Anne, Pietras, Kristian, Levin, Max, Vargeese, Chandra, Green, Louis S, Bergqvist, David, Östman, Arne, Heldin, Carl-Henrik

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Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication von MORRISSEY, David V, BLANCHARD, Karin, POLISKY, Barry A, ZINNEN, Shawn, SHAW, Lucinda, JENSEN, Kristi, LOCKRIDGE, Jennifer A, DICKINSON, Brent, MCSWIGGEN, James A, VARGEESE, Chandra, BOWMAN, Keith, SHAFFER, Chris S

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P.193 Phosphoryl guanidine-containing backbone modifications enhance exon skipping, dystrophin restoration and survival in a severe mouse model for DMD von Hu, X., Kandasamy, P., McClorey, G., Shimizu, M., Kothari, N., Iwamoto, N., Byrne, M., Liu, F., Longo, K., Oieni, J., Shivalila, C., Rinaldi, C., Yang, H., Wood, M., Vargeese, C.

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THU-030 - Stereochemistry enhances pharmacological properties of APOC3 antisense oligonucleotides von Apponi, L., Iwamoto, N., Frank-Kamenetsky, M., Yang, H., Braun, M., Shah, A., Butler, D., Lu, G., Vathipadiekal, V., Menon, S., Bowman, K., Pittet, L., Zhang, J., Zhong, Z., Vargeese, C., Standley, S.

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Stereochemistry enhances pharmacological properties of APOC3 antisense oligonucleotides von Apponi, L., Iwamoto, N., Frank-Kamenetsky, M., Yang, H., Braun, M., Shah, A., Butler, D., Lu, G., Vathipadiekal, V., Menon, S., Bowman, K., Pittet, L., Zhang, J., Zhong, Z., Vargeese, C., Standley, S.

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Preclinical studies of WVE-210201, an investigational stereopure antisense oligonucleotide in development for the treatment of patients with duchenne muscular dystrophy (DMD) von Panzara, M., Zhang, J., Rinaldi, C., McClorey, G., Bowman, K., Butler, D., Dodart, J., Frank-Kamenetsky, M., Iwamoto, N., Kothari, N., Lu, G., Mathieu, S., M, M., Melkonian, M., Menon, S., Standley, S., Yang, H., Zhong, Z., Wood, M., Vargeese, C.

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P.402 - WVE-210201, an investigational stereopure oligonucleotide therapy for Duchenne muscular dystrophy, induces Exon 51 skipping and dystrophin protein restoration von Wood, M., Zhang, J., Bowman, K., Butler, D., Rinaldi, C., McClorey, G., Frank-Kamenetsky, M., Iwamoto, N., Kothari, N., Lu, G., Mathieu, S., Meena, M., Menon, S., Shimizu, M., Standley, S., Yang, H., Zhong, Z., Francis, C., Vargeese, C.

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Characterization of nuclease-resistant ribozymes directed against hepatitis B virus RNA von Morrissey, D. V., Lee, P. A., Johnson, D. A., Overly, S. L., McSwiggen, J. A., Beigelman, L., Mokler, V. R., Maloney, L., Vargeese, C., Bowman, K., O'Brien, J. T., Shaffer, C. S., Conrad, A., Schmid, P., Morrey, J. D., Macejak, D. G., Pavco, P. A., Blatt, L. M.

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DMD CLINICAL THERAPIES II von Durbin, A., Shivalila, C., Kothari, N., Rinaldi, C., McClorey, G., Antonijevic, I., Byrne, M., Davis II, J., Guo, L., Iwamoto, N., Liu, F., Longo, K., Lu, G., Nadella, P., Purcell-Estabrook, E., Standley, S., Zhong, Z., Zhang, J., Wood, M., Vargeese, C.

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DMD CLINICAL THERAPIES II: P.127Identification of potent, muscle-targeting investigational stereo-pure oligonucleotides for exon 53 DMD therapy von Durbin, A., Shivalila, C., Kothari, N., Rinaldi, C., McClorey, G., Antonijevic, I., Byrne, M., Davis II, J., Guo, L., Iwamoto, N., Liu, F., Longo, K., Lu, G., Nadella, P., Purcell-Estabrook, E., Standley, S., Zhong, Z., Zhang, J., Wood, M., Vargeese, C.

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Novel approach to specific growth factor inhibition in vivo : Antagonism of platelet-derived growth factor in glomerulonephritis by aptamers von FLOEGE, J, OSTENDORF, T, JANSSEN, U, BURG, M, RADEKE, H. H, VARGEESE, C, GILL, S. C, GREEN, L. S, JANJIC, N

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Efficient activation of nucleoside phosphoramidites with 4,5-dicyanoimidazole during oligonucleotide synthesis von Vargeese, Chandra, Carter, Jeff, Yegge, John, Krivjansky, Shira, Settle, Alecia, Kropp, Eric, Peterson, Kent, Pieken, Wolfgang

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Potent 2'-Amino-2'-deoxypyrimidine RNA Inhibitors of Basic Fibroblast Growth Factor von Jellinek, Derek, Green, Louis S, Bell, Carol, Lynott, C. Kate, Gill, Nicole, Vargeese, Chandra, Kirschenheuter, Gary, McGee, Daniel P. C, Abesinghe, Padmapriya

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978 Development of siRNA as a therapeutic for hepatitis C von Morrissey, David V., Jensen, Kristi, Zinnen, Shawn, Dickinson, Brent, Hartsough, Kim, Shaw, Cindy, McSwiggen, James A., Vargeese, Chandra, Bowman, Keith, Shaffer, Chris S., Polisky, Barry, Lockridge, Jennifer A.

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Chemistry of L-ascorbic and D-isoascorbic acids. IV, an efficient synthesis of 2-deoxypentofuranoses von VARGEESE, C, ABUSHANAB, E

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Chemistry of L-ascorbic and D-isoascorbic acids. 4. An efficient synthesis of 2-deoxypentofuranoses von Vargeese, Chandra, Abushanab, Elie

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Synthesis and Biological Evaluation of 1‘,2‘-Seconucleo-5‘-phosphonates von Racha, Saibaba, Vargeese, Chandra, Vemishetti, Purushotham, El-Subbagh, Hussein I, Abushanab, Elie, Panzica, Raymond P

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