Molecular Pathways: Adiponectin and Leptin Signaling in Cancer von VANSAUN, Michael N

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Modulation of the leptin receptor mediates tumor growth and migration of pancreatic cancer cells von Mendonsa, Alisha M, Chalfant, Madeleine C, Gorden, Lee D, VanSaun, Michael N

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Increased diacylglycerols characterize hepatic lipid changes in progression of human nonalcoholic fatty liver disease; comparison to a murine model von Gorden, D Lee, Ivanova, Pavlina T, Myers, David S, McIntyre, J Oliver, VanSaun, Michael N, Wright, J Kelly, Matrisian, Lynn M, Brown, H Alex

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Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer von Nagathihalli, Nagaraj S, Castellanos, Jason A, Lamichhane, Purushottam, Messaggio, Fanuel, Shi, Chanjuan, Dai, Xizi, Rai, Priyamvada, Chen, Xi, VanSaun, Michael N, Merchant, Nipun B

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Hepatocellular proliferation correlates with inflammatory cell and cytokine changes in a murine model of nonalchoholic fatty liver disease von Vansaun, Michael N, Mendonsa, Alisha M, Lee Gorden, D

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Pancreatic stellate cell secreted IL-6 stimulates STAT3 dependent invasiveness of pancreatic intraepithelial neoplasia and cancer cells von Nagathihalli, Nagaraj S, Castellanos, Jason A, VanSaun, Michael N, Dai, Xizi, Ambrose, Mahogany, Guo, Qiaozhi, Xiong, Yanhua, Merchant, Nipun B

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Adiponectin receptor agonists inhibit leptin induced pSTAT3 and in vivo pancreatic tumor growth von Messaggio, Fanuel, Mendonsa, Alisha M, Castellanos, Jason, Nagathihalli, Nagaraj S, Gorden, Lee, Merchant, Nipun B, VanSaun, Michael N

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Reprogramming of mesenchymal stem cells by the synovial sarcoma-associated oncogene SYT-SSX2 von Garcia, C B, Shaffer, C M, Alfaro, M P, Smith, A L, Sun, J, Zhao, Z, Young, P P, VanSaun, M N, Eid, J E

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High Fat Diet Induced Hepatic Steatosis Establishes a Permissive Microenvironment for Colorectal Metastases and Promotes Primary Dysplasia in a Murine Model von VanSaun, Michael Nathan, Lee, In Kyu, Washington, Mary Kay, Matrisian, Lynn, Gorden, David Lee

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Urolithin A, a Novel Natural Compound to Target PI3K/AKT/mTOR Pathway in Pancreatic Cancer von Totiger, Tulasigeri M, Srinivasan, Supriya, Jala, Venkatakrishna R, Lamichhane, Purushottam, Dosch, Austin R, Gaidarski, 3rd, Alexander A, Joshi, Chandrashekhar, Rangappa, Shobith, Castellanos, Jason, Vemula, Praveen Kumar, Chen, Xi, Kwon, Deukwoo, Kashikar, Nilesh, VanSaun, Michael, Merchant, Nipun B, Nagathihalli, Nagaraj S

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Host and tumor derived MMP13 regulate extravasation and establishment of colorectal metastases in the liver von Mendonsa, Alisha M, VanSaun, Michael N, Ustione, Alessandro, Piston, David W, Fingleton, Barbara M, Gorden, David Lee

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Synthetic adiponectin-receptor agonist, AdipoRon, induces glycolytic dependence in pancreatic cancer cells von Manley, Sharon J., Olou, Appolinaire A., Jack, Jarrid L., Ruckert, Mariana T., Walsh, R. McKinnon, Eades, Austin E., Bye, Bailey A., Ambrose, Joe, Messaggio, Fanuel, Anant, Shrikant, VanSaun, Michael N.

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Combined Blockade of MEK and CDK4/6 Pathways Induces Senescence to Improve Survival in Pancreatic Ductal Adenocarcinoma von Willobee, Brent A, Gaidarski, Alexander A, Dosch, Austin R, Castellanos, Jason A, Dai, Xizi, Mehra, Siddharth, Messaggio, Fanuel, Srinivasan, Supriya, VanSaun, Michael N, Nagathihalli, Nagaraj S, Merchant, Nipun B

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Abstract 3168: Pancreatic cancer lipid theft is mediated by MAP Kinase signaling in adipocytes von Ambrose, Joseph, Eades, Austin E., Walsh, McKinnon, VanSaun, Michael N.

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Tobacco Carcinogen-Induced Production of GM-CSF Activates CREB to Promote Pancreatic Cancer von Srinivasan, Supriya, Totiger, Tulasigeri, Shi, Chanjuan, Castellanos, Jason, Lamichhane, Purushottam, Dosch, Austin R, Messaggio, Fanuel, Kashikar, Nilesh, Honnenahally, Kumaraswamy, Ban, Yuguang, Merchant, Nipun B, VanSaun, Michael, Nagathihalli, Nagaraj S

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Targeting the Wnt pathway in synovial sarcoma models von Barham, Whitney, Frump, Andrea L, Sherrill, Taylor P, Garcia, Christina B, Saito-Diaz, Kenyi, VanSaun, Michael N, Fingleton, Barbara, Gleaves, Linda, Orton, Darren, Capecchi, Mario R, Blackwell, Timothy S, Lee, Ethan, Yull, Fiona, Eid, Josiane E

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Correction: Synthetic adiponectin-receptor agonist, AdipoRon, induces glycolytic dependence in pancreatic cancer cells von Manley, Sharon J., Olou, Appolinaire A., Jack, Jarrid L., Ruckert, Mariana T., Walsh, R. McKinnon, Eades, Austin E., Bye, Bailey A., Ambrose, Joe, Messaggio, Fanuel, Anant, Shrikant, VanSaun, Michael N.

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Tu1419 INTERRUPTING NEURAL-TUMOR SIGNALING LOOP BY TARGETING HISTAMINE RECEPTOR-1 IN PANCREATIC DUCTAL ADENOCARCINOMA von Ghosh, Hindole, Veeragoni, Dileepkumar, Bhattacharyya, Sangita, Hamza, Ameer, Kasi, Anup, VanSaun, Michael, Weir, Scott, Bossmann, Stefan H., Dandawate, Prasad

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Abstract 2467: Adiponectin receptor agonism induces a metabolic switch in pancreatic cancer cells from oxidative phosphorylation to glycolysis von Manley, Sharon J., Jack, Jarrid, Ambrose, Joseph, Olou, Appolinaire A., VanSaun, Michael N.

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Abstract 2824: SHP2-PDHA metabolic axis is critical for adipocyte function by mitigating ER stress-induced adipocytes dysfunction: Implication for obesity-driven pancreatic ductal... von Olou, Appolinaire A., Jack, Jarrid, Manley, Sharon, Ambrose, Joseph, Walsh, McKinnon, Eades, Austin, VanSaun, Michael N.

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