A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins von Kirkland, David, Reeve, Lesley, Gatehouse, David, Vanparys, Philippe

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How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop von Kirkland, David, Pfuhler, Stefan, Tweats, David, Aardema, Marilyn, Corvi, Raffaella, Darroudi, Firouz, Elhajouji, Azeddine, Glatt, Hansruedi, Hastwell, Paul, Hayashi, Makoto, Kasper, Peter, Kirchner, Stephan, Lynch, Anthony, Marzin, Daniel, Maurici, Daniela, Meunier, Jean-Roc, Müller, Lutz, Nohynek, Gerhard, Parry, James, Parry, Elizabeth, Thybaud, Veronique, Tice, Ray, van Benthem, Jan, Vanparys, Philippe, White, Paul

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Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities—Report from an ECVAM workshop von Pfuhler, Stefan, Kirkland, David, Kasper, Peter, Hayashi, Makoto, Vanparys, Philippe, Carmichael, Paul, Dertinger, Stephen, Eastmond, David, Elhajouji, Azeddine, Krul, Cyrille, Rothfuss, Andreas, Schoening, Gabriele, Smith, Andrew, Speit, Guenter, Thomas, Claire, van Benthem, Jan, Corvi, Raffaella

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Automated analysis of contractility in the embryonic stem cell test, a novel approach to assess embryotoxicity von Peters, Annelieke K., Wouwer, Gert Van de, Weyn, Barbara, Verheyen, Geert R., Vanparys, Philippe, Gompel, Jacques Van

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Preface von Corvi, Raffaella, Vanparys, Philippe

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Interlaboratory validation of the ToxTracker assay: An in vitro reporter assay for mechanistic genotoxicity assessment von Hendriks, Giel, Adriaens, Els, Allemang, Ashley, Clements, Julie, Cole, Gabrielle, Derr, Remco, Engel, Maria, Hamel, Annie, Kidd, Darren, Kellum, Stephanie, Kiyota, Tomomi, Myhre, Abby, Naëssens, Valerie, Pfuhler, Stefan, Roy, Marise, Settivari, Raja, Schuler, Maik, Zeller, Andreas, Benthem, Jan, Vanparys, Philippe, Kirkland, David

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Improvement of the Bovine Corneal Opacity and Permeability (BCOP) assay as an in vitro alternative to the Draize rabbit eye irritation test von Verstraelen, Sandra, Jacobs, An, De Wever, Bart, Vanparys, Philippe

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Can in vitro mammalian cell genotoxicity test results be used to complement positive results in the Ames test and help predict carcinogenic or in vivo genotoxic activity? I. Report... von Kirkland, David, Zeiger, Errol, Madia, Federica, Gooderham, Nigel, Kasper, Peter, Lynch, Anthony, Morita, Takeshi, Ouedraogo, Gladys, Parra Morte, Juan Manuel, Pfuhler, Stefan, Rogiers, Vera, Schulz, Markus, Thybaud, Veronique, van Benthem, Jan, Vanparys, Philippe, Worth, Andrew, Corvi, Raffaella

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A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment von Ates, Gamze, Mertens, Birgit, Heymans, Anja, Verschaeve, Luc, Milushev, Dimiter, Vanparys, Philippe, Roosens, Nancy H. C., De Keersmaecker, Sigrid C. J., Rogiers, Vera, Doktorova, Tatyana Y.

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Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics von Vanparys, Philippe, Corvi, Raffaella, Aardema, Marilyn J., Gribaldo, Laura, Hayashi, Makoto, Hoffmann, Sebastian, Schechtman, Leonard

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A review of the implementation of the embryonic stem cell test (EST). The report and recommendations of an ECVAM/ReProTect Workshop von Marx-Stoelting, Philip, Adriaens, Els, Ahr, Hans-Jürgen, Bremer, Susanne, Garthoff, Bernward, Gelbke, Heinz-Peter, Piersma, Aldert, Pellizzer, Cristian, Reuter, Ulrike, Rogiers, Vera, Schenk, Barbara, Schwengberg, Silke, Seiler, Andrea, Spielmann, Horst, Steemans, Margino, Stedman, Donald B, Vanparys, Philippe, Vericat, Joan Albert, Verwei, Miriam, van der Water, Femke, Weimer, Marc, Schwarz, Michael

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Development of a new opacitometer for the bovine corneal opacity and permeability (BCOP) assay von Van Goethem, Freddy, Hansen, Erik, Sysmans, Marc, De Smedt, Ann, Vanparys, Philippe, Van Gompel, Jacky

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ECVAM prevalidation of three cell transformation assays von Vanparys, Philippe, Corvi, Raffaella, Aardema, Marilyn, Gribaldo, Laura, Hayashi, Makoto, Hoffmann, Sebastian, Schechtman, Leonard

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The practical application of three validated in vitro embryotoxicity tests. The report and recommendations of an ECVAM/ZEBET workshop (ECVAM workshop 57) von Spielmann, Horst, Seiler, Andrea, Bremer, Susanne, Hareng, Lars, Hartung, Thomas, Ahr, Hans, Faustman, Elaine, Haas, Ulla, Moffat, Graeme J, Nau, Heinz, Vanparys, Philippe, Piersma, Aldert, Sintes, Juan Riego, Stuart, Jane

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ECVAM and Pharmaceuticals von Vanparys, Philippe

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State of the art in developmental toxicity screening methods and a way forward: a meeting report addressing embryonic stem cells, whole embryo culture, and zebrafish von Chapin, Robert, Augustine-Rauch, Karen, Beyer, Bruce, Daston, George, Finnell, Richard, Flynn, Thomas, Hunter, Sidney, Mirkes, Phillip, Sue O'Shea, K., Piersma, Aldert, Sandler, David, Vanparys, Philippe, Van Maele-Fabry, Geneviève

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Regulatory assessment of in vitro skin corrosion and irritation data within the European framework: Workshop recommendations von Eskes, Chantra, Detappe, Véronique, Koëter, Herman, Kreysa, Joachim, Liebsch, Manfred, Zuang, Valérie, Amcoff, Patric, Barroso, João, Cotovio, José, Guest, Robert, Hermann, Martina, Hoffmann, Sebastian, Masson, Philippe, Alépée, Nathalie, Arce, Luis Alfonso, Brüschweiler, Beat, Catone, Tiziana, Cihak, Rostislav, Clouzeau, Jack, D’Abrosca, Federica, Delveaux, Cédric, Derouette, Jean Paul, Engelking, Oliver, Facchini, Davide, Fröhlicher, Mirjam, Hofmann, Markus, Hopf, Nancy, Molinari, Jennifer, Oberli, Aurelia, Ott, Matthieu, Peter, Ronald, Sá-Rocha, Vanessa M., Schenk, Dominique, Tomicic, Catherine, Vanparys, Philippe, Verdon, Bernadette, Wallenhorst, Thomas, Winkler, Gian Christian, Depallens, Olivier

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Eye irritation von Eskes, Chantra, Bessou, Sandrine, Bruner, Leon, Curren, Rodger, Harbell, John, Jones, Penny, Kreiling, Reinhard, Liebsch, Manfred, McNamee, Pauline, Pape, Wolfang, Prinsen, Menk K, Seidle, Troy, Vanparys, Philippe, Worth, Andrew, Zuang, Valérie

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The micronucleus assay as a test for the detection of aneugenic activity von Vanparys, Philippe, Vermeiren, Felix, Sysmans, Marc, Temmerman, Roland

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A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing von Basketter, David A, Clewell, Harvey, Kimber, Ian, Rossi, Annamaria, Blaauboer, Bas, Burrier, Robert, Daneshian, Mardas, Eskes, Chantra, Goldberg, Alan, Hasiwa, Nina, Hoffmann, Sebastian, Jaworska, Joanna, Knudsen, Thomas B, Landsiedel, Robert, Leist, Marcel, Locke, Paul, Maxwell, Gavin, McKim, James, McVey, Emily A, Ouédraogo, Gladys, Patlewicz, Grace, Pelkonen, Olavi, Roggen, Erwin, Rovida, Costanza, Ruhdel, Irmela, Schwarz, Michael, Schepky, Andreas, Schoeters, Greet, Skinner, Nigel, Trentz, Kerstin, Turner, Marian, Vanparys, Philippe, Yager, James, Zurlo, Joanne, Hartung, Thomas

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