Bone marrow stromal cell–derived exosomes as communicators in drug resistance in multiple myeloma cells von Wang, Jinheng, Hendrix, An, Hernot, Sophie, Lemaire, Miguel, De Bruyne, Elke, Van Valckenborgh, Els, Lahoutte, Tony, De Wever, Olivier, Vanderkerken, Karin, Menu, Eline

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Exosomes play a role in multiple myeloma bone disease and tumor development by targeting osteoclasts and osteoblasts von Faict, Sylvia, Muller, Joséphine, De Veirman, Kim, De Bruyne, Elke, Maes, Ken, Vrancken, Louise, Heusschen, Roy, De Raeve, Hendrik, Schots, Rik, Vanderkerken, Karin, Caers, Jo, Menu, Eline

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Loss of RASSF4 Expression in Multiple Myeloma Promotes RAS-Driven Malignant Progression von De Smedt, Eva, Maes, Ken, Verhulst, Stefaan, Lui, Hui, Kassambara, Alboukadel, Maes, Anke, Robert, Nicolas, Heirman, Carlo, Cakana, Andrew, Hose, Dirk, Breckpot, Karine, van Grunsven, Leo A, De Veirman, Kim, Menu, Eline, Vanderkerken, Karin, Moreaux, Jérôme, De Bruyne, Elke

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Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features von Azab, Abdel Kareem, Hu, Jinsong, Quang, Phong, Azab, Feda, Pitsillides, Costas, Awwad, Rana, Thompson, Brian, Maiso, Patricia, Sun, Jessica D., Hart, Charles P., Roccaro, Aldo M., Sacco, Antonio, Ngo, Hai T., Lin, Charles P., Kung, Andrew L., Carrasco, Ruben D., Vanderkerken, Karin, Ghobrial, Irene M.

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Dendritic Cell-Based Immunotherapy in Multiple Myeloma: Challenges, Opportunities, and Future Directions von Verheye, Emma, Bravo Melgar, Jesús, Deschoemaeker, Sofie, Raes, Geert, Maes, Anke, De Bruyne, Elke, Menu, Eline, Vanderkerken, Karin, Laoui, Damya, De Veirman, Kim

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Targeting mTOR signaling pathways in multiple myeloma: biology and implication for therapy von Wang, Yanmeng, Vandewalle, Niels, De Veirman, Kim, Vanderkerken, Karin, Menu, Eline, De Bruyne, Elke

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S-adenosylmethionine biosynthesis is a targetable metabolic vulnerability in multiple myeloma von Wang, Yanmeng, Muylaert, Catharina, Wyns, Arne, Vlummens, Philip, De Veirman, Kim, Vanderkerken, Karin, Zaal, Esther, Berkers, Celia, Moreaux, Jérome, De Bruyne, Elke, Menu, Eline

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The therapeutic potential of cell cycle targeting in multiple myeloma von Maes, Anke, Menu, Eline, Veirman, Kim De, Maes, Ken, Vand Erkerken, Karin, De Bruyne, Elke

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A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma von Nylund, Patrick, Atienza Párraga, Alba, Haglöf, Jakob, De Bruyne, Elke, Menu, Eline, Garrido-Zabala, Berta, Ma, Anqi, Jin, Jian, Öberg, Fredrik, Vanderkerken, Karin, Kalushkova, Antonia, Jernberg-Wiklund, Helena

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Inhibiting Dickkopf‐1 (Dkk1) Removes Suppression of Bone Formation and Prevents the Development of Osteolytic Bone Disease in Multiple Myeloma von Heath, Deborah J, Chantry, Andrew D, Buckle, Clive H, Coulton, Les, Shaughnessy, John D, Evans, Holly R, Snowden, John A, Stover, David R, Vanderkerken, Karin, Croucher, Peter I

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Bone Marrow-Derived Mesenchymal Stromal Cells are Attracted by Multiple Myeloma Cell-Produced Chemokine CCL25 and Favor Myeloma Cell Growth in Vitro and In Vivo von Xu, Song, Menu, Eline, Becker, Ann De, Van Camp, Ben, Vanderkerken, Karin, Van Riet, Ivan

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Extracellular vesicle cross-talk in the bone marrow microenvironment: implications in multiple myeloma von Wang, Jinheng, Faict, Sylvia, Maes, Ken, De Bruyne, Elke, Van Valckenborgh, Els, Schots, Rik, Vanderkerken, Karin, Menu, Eline

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Pyrroline-5-Carboxylate Reductase 1: a novel target for sensitizing multiple myeloma cells to bortezomib by inhibition of PRAS40-mediated protein synthesis von Oudaert, Inge, Satilmis, Hatice, Vlummens, Philip, De Brouwer, Wouter, Maes, Anke, Hose, Dirk, De Bruyne, Elke, Ghesquière, Bart, Vanderkerken, Karin, De Veirman, Kim, Menu, Eline

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Exosomes in multiple myeloma: from bench to bedside von Menu, Eline, Vanderkerken, Karin

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A GRP78-Directed Monoclonal Antibody Recaptures Response in Refractory Multiple Myeloma with Extramedullary Involvement von Rasche, Leo, Menoret, Emmanuelle, Dubljevic, Valentina, Menu, Eline, Vanderkerken, Karin, Lapa, Constantin, Steinbrunn, Torsten, Chatterjee, Manik, Knop, Stefan, Düll, Johannes, Greenwood, Deanne L, Hensel, Frank, Rosenwald, Andreas, Einsele, Hermann, Brändlein, Stephanie

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Epigenetic Modifiers: Anti-Neoplastic Drugs With Immunomodulating Potential von Maes, Ken, Mondino, Anna, Lasarte, Juan Jose, Agirre, Xabier, Vanderkerken, Karin, Prosper, Felipe, Breckpot, Karine

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The myeloma stem cell concept, revisited: from phenomenology to operational terms von Johnsen, Hans Erik, Bøgsted, Martin, Schmitz, Alexander, Bødker, Julie Støve, El-Galaly, Tarec Christoffer, Johansen, Preben, Valent, Peter, Zojer, Niklas, Van Valckenborgh, Els, Vanderkerken, Karin, van Duin, Mark, Sonneveld, Pieter, Perez-Andres, Martin, Orfao, Alberto, Dybkær, Karen

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The Epigenome in Multiple Myeloma: Impact on Tumor Cell Plasticity and Drug Response von De Smedt, Eva, Lui, Hui, Maes, Ken, De Veirman, Kim, Menu, Eline, Vanderkerken, Karin, De Bruyne, Elke

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Upregulation of miR-135b is involved in the impaired osteogenic differentiation of mesenchymal stem cells derived from multiple myeloma patients von Xu, Song, Cecilia Santini, Gaia, De Veirman, Kim, Vande Broek, Isabelle, Leleu, Xavier, De Becker, Ann, Van Camp, Ben, Vanderkerken, Karin, Van Riet, Ivan

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Activation of ATF4 mediates unwanted Mcl-1 accumulation by proteasome inhibition von Hu, Jinsong, Dang, Nana, Menu, Eline, De Bryune, Elke, Xu, Dehui, Van Camp, Ben, Van Valckenborgh, Els, Vanderkerken, Karin

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