Chromosomal rearrangements involving the NTRK1 gene in colorectal carcinoma von Créancier, Laurent, Vandenberghe, Isabelle, Gomes, Bruno, Dejean, Caroline, Blanchet, Jean-Christophe, Meilleroux, Julie, Guimbaud, Rosine, Selves, Janick, Kruczynski, Anna

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Melanoma chemotherapy leads to the selection of ABCB5-expressing cells von Chartrain, Marine, Riond, Joëlle, Stennevin, Aline, Vandenberghe, Isabelle, Gomes, Bruno, Lamant, Laurence, Meyer, Nicolas, Gairin, Jean Edouard, Guilbaud, Nicolas, Annereau, Jean Philippe

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Actinic keratosis modelling in mice: A translational study von Pillon, Arnaud, Gomes, Bruno, Vandenberghe, Isabelle, Cartron, Valérie, Cèbe, Patrick, Blanchet, Jean-Christophe, Sibaud, Vincent, Guilbaud, Nicolas, Audoly, Laurent, Lamant, Laurence, Kruczynski, Anna

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Physalin B, a novel inhibitor of the ubiquitin-proteasome pathway, triggers NOXA-associated apoptosis von Vandenberghe, Isabelle, Créancier, Laurent, Vispé, Stéphane, Annereau, Jean-Philippe, Barret, Jean-Marc, Pouny, Isabelle, Samson, Arnaud, Aussagues, Yannick, Massiot, Georges, Ausseil, Frédéric, Bailly, Christian, Kruczynski, Anna

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315 W0180 novel anti-VISTA antibody: Rationale for target patient population and first-in-human trial design in monotherapy and in combination with anti-PD1 antibody von Melero, Ignacio, Gomez-Roca, Carlos, Ferre, Pierre, Chetaille, Eric, Petain, Aurelie, Thuilliez, Celine, Vandenberghe, Isabelle, Cruzalegui, Francisco, Boudribila, Asmaa, Pavlyuk, Mariya, Marabelle, Aurelien

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Proteasome Inhibitors from Neoboutonia melleri von Long, Christophe, Beck, Joséphine, Cantagrel, Frédéric, Marcourt, Laurence, Vendier, Laure, David, Bruno, Plisson, Fabien, Derguini, Fadila, Vandenberghe, Isabelle, Aussagues, Yannick, Ausseil, Frédéric, Lavaud, Catherine, Sautel, François, Massiot, Georges

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Semisynthetic neoboutomellerone derivatives as ubiquitin-proteasome pathway inhibitors von Beck, Joséphine, Guminski, Yves, Long, Christophe, Marcourt, Laurence, Derguini, Fadila, Plisson, Fabien, Grondin, Antonio, Vandenberghe, Isabelle, Vispé, Stéphane, Brel, Viviane, Aussagues, Yannick, Ausseil, Frédéric, Arimondo, Paola B., Massiot, Georges, Sautel, François, Cantagrel, Frédéric

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High-Throughput Bioluminescence Screening of Ubiquitin-Proteasome Pathway Inhibitors from Chemical and Natural Sources von Ausseil, Frederic, Samson, Arnaud, Aussagues, Yannick, Vandenberghe, Isabelle, Creancier, Laurent, Pouny, Isabelle, Kruczynski, Anna, Massiot, Georges, Bailly, Christian

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Tumor Cells Hijack Macrophage-Produced Complement C1q to Promote Tumor Growth von Roumenina, Lubka T, Daugan, Marie V, Noé, Rémi, Petitprez, Florent, Vano, Yann A, Sanchez-Salas, Rafaël, Becht, Etienne, Meilleroux, Julie, Clec'h, Bénédicte Le, Giraldo, Nicolas A, Merle, Nicolas S, Sun, Cheng-Ming, Verkarre, Virginie, Validire, Pierre, Selves, Janick, Lacroix, Laetitia, Delfour, Olivier, Vandenberghe, Isabelle, Thuilliez, Celine, Keddani, Sonia, Sakhi, Imene B, Barret, Eric, Ferré, Pierre, Corvaïa, Nathalie, Passioukov, Alexandre, Chetaille, Eric, Botto, Marina, de Reynies, Aurélien, Oudard, Stephane Marie, Mejean, Arnaud, Cathelineau, Xavier, Sautès-Fridman, Catherine, Fridman, Wolf H

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Abstract 2400: K01401-020 is a novel anti-VISTA antibody for cancer treatment: Pharmacodynamic impact on non-human primates and human immune system von Loukili, Noureddine, Vandenberghe, Isabelle, Delfour, Olivier, Fraboul, Françoise, Chetaille, Eric, Cruzalegui, Francisco, Corvaïa, Nathalie, Ferré, Pierre J.

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Abstract 5531: K0401-020 anti-VISTA antibody monotherapy increases specific CD8 T cell response in non-human primates von Libon, Christine, Vandenberghe, Isabelle, Marlin, Romain, Gros, Wesley, Leonec, Marco, Gomez-Pacheco, Mario, Gallouet, Anne-Sophie, Fraboul, Françoise, Mahfoudi, Abderrahim, Dereuddre-Bosquet, Nathalie, Ferré, Pierre

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F14512, a polyamine-vectorized inhibitor of topoisomerase II, exhibits a marked anti-tumor activity in ovarian cancer von Thibault, Benoît, Clement, Emily, Zorza, Grégoire, Meignan, Samuel, Delord, Jean-Pierre, Couderc, Bettina, Bailly, Christian, Narducci, Fabrice, Vandenberghe, Isabelle, Kruczynski, Anna, Guilbaud, Nicolas, Ferré, Pierre, Annereau, Jean-Philippe

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Abstract 4265: Identification of new NTRK1 gene fusion as oncogene target in colon cancer von Creancier, Laurent, Dejean, Caroline, Vandenberghe, Isabelle, Blanchet, Jean-Christophe, Aussagues, Yannick, Annereau, Jean Philippe, Selves, Janick, Kruczynski, Anna

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Preclinical activity of F14512, designed to target tumors expressing an active polyamine transport system von Kruczynski, Anna, Vandenberghe, Isabelle, Pillon, Arnaud, Pesnel, Sabrina, Goetsch, Liliane, Barret, Jean-Marc, Guminski, Yves, Le Pape, Alain, Imbert, Thierry, Bailly, Christian, Guilbaud, Nicolas

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Discovery Bioanalysis and In Vivo Pharmacology as an Integrated Process: A Case Study in Oncology Drug Discovery von Grondin, Antonio, Pillon, Arnaud, Vandenberghe, Isabelle, Guilbaud, Nicolas, Kruczynski, Anna, Gomes, Bruno

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Discovery bioanalysis and von Grondin, Antonio, Pillon, Arnaud, Vandenberghe, Isabelle, Guilbaud, Nicolas, Kruczynski, Anna, Gomes, Bruno

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Abstract LB-295: Identification of the first class of proteasome inhibitors that impair 26S proteasome assembly in vitro von Etievant, Chantal, Riquet, William, Roullet, Nicolas, Knibiehler, Martine, Vandenberghe, Isabelle, Carletti, Isabelle, Gairin, Jean Edouard

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Abstract 988: F14512, a novel vectorized topoiserase II inhibitor, bypasses MDR1 mediated resistance von Annereau, Jean Philippe, Brel, Viviane, Riquet, William, Créancier, Laurent, Vandenberghe, Isabelle, Fournier, Emmanuel, Robichon, Céline, Stennevin, Aline, Offrete, Vanessa, Lacastaigneratte, Laurence, Gomes, Bruno, Kruczynski, Anna, Bailly, Christian, Guilbaud, Nicolas

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Abstract B37: F14512, a polyamine-vectorized anticancer drug, triggers senescence cell death mechanism von Brel, Viviane, Annereau, J-Philippe, Gomes, Bruno, Vandenberghe, Isabelle, Andre, Karine, Marionneau, Marie-Laure, Lacastaigneratte, Laurence, Stennevin, Aline, Rouquet, Jerome, Latil, Alain, Kruczynski, Anna, Bailly, Christian, Guilbaud, Nicolas

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Abstract 3261: Novel hemisynthetic derivatives of Amaryllidaceae alkaloids exert antitumor activity on xenograft melanoma models von Annereau, Jean-Philippe, Marion, Frédéric, Fournier, Emmanuel, Vandenberghe, Isabelle, Vispé, Stéphane, Pouny, Isabelle, Sautel, François, Aussagues, Yannick, Ausseil, Frédéric, Gomes, Bruno, Fahy, Jacques, Bailly, Christian, Kruczynski, Anna, Guilbaud, Nicolas

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