hERG K(+) channels: structure, function, and clinical significance von Vandenberg, Jamie I, Perry, Matthew D, Perrin, Mark J, Mann, Stefan A, Ke, Ying, Hill, Adam P

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Towards a Structural View of Drug Binding to hERG K+ Channels von Vandenberg, Jamie I., Perozo, Eduardo, Allen, Toby W.

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Assessing drug safety by identifying the axis of arrhythmia in cardiomyocyte electrophysiology von Heitmann, Stewart, Vandenberg, Jamie I, Hill, Adam P

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Molecular Docking Guided Grid-Independent Descriptor Analysis to Probe the Impact of Water Molecules on Conformational Changes of hERG Inhibitors in Drug Trapping Phenomenon von Munawar, Saba, Vandenberg, Jamie I, Jabeen, Ishrat

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A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm von Fermini, Bernard, Hancox, Jules C., Abi-Gerges, Najah, Bridgland-Taylor, Matthew, Chaudhary, Khuram W., Colatsky, Thomas, Correll, Krystle, Crumb, William, Damiano, Bruce, Erdemli, Gul, Gintant, Gary, Imredy, John, Koerner, John, Kramer, James, Levesque, Paul, Li, Zhihua, Lindqvist, Anders, Obejero-Paz, Carlos A., Rampe, David, Sawada, Kohei, Strauss, David G., Vandenberg, Jamie I.

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Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics von Chiamvimonvat, Nipavan, Chen‐Izu, Ye, Clancy, Colleen E., Deschenes, Isabelle, Dobrev, Dobromir, Heijman, Jordi, Izu, Leighton, Qu, Zhilin, Ripplinger, Crystal M., Vandenberg, Jamie I., Weiss, James N., Koren, Gideon, Banyasz, Tamas, Grandi, Eleonora, Sanguinetti, Michael C., Bers, Donald M., Nerbonne, Jeanne M.

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Arrhythmogenic effects of ultra-long and bistable cardiac action potentials von Heitmann, Stewart, Shpak, Anton, Vandenberg, Jamie, Hill, Adam P.

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Development of automated patch clamp assays to overcome the burden of variants of uncertain significance in inheritable arrhythmia syndromes von Ma, Joanne G, Vandenberg, Jamie I, Ng, Chai-Ann

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Potassium channels in the heart: structure, function and regulation von Grandi, Eleonora, Sanguinetti, Michael C., Bartos, Daniel C., Bers, Donald M., Chen‐Izu, Ye, Chiamvimonvat, Nipavan, Colecraft, Henry M., Delisle, Brian P., Heijman, Jordi, Navedo, Manuel F., Noskov, Sergei, Proenza, Catherine, Vandenberg, Jamie I., Yarov‐Yarovoy, Vladimir

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Structural basis of promiscuous substrate transport by Organic Cation Transporter 1 von Zeng, Yi C., Sobti, Meghna, Quinn, Ada, Smith, Nicola J., Brown, Simon H. J., Vandenberg, Jamie I., Ryan, Renae M., O’Mara, Megan L., Stewart, Alastair G.

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High-throughput discovery of trafficking-deficient variants in the cardiac potassium channel KV11.1 von Kozek, Krystian A., Glazer, Andrew M., Ng, Chai-Ann, Blackwell, Daniel, Egly, Christian L., Vanags, Loren R., Blair, Marcia, Mitchell, Devyn, Matreyek, Kenneth A., Fowler, Douglas M., Knollmann, Bjorn C., Vandenberg, Jamie I., Roden, Dan M., Kroncke, Brett M.

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Potassium dependent structural changes in the selectivity filter of HERG potassium channels von Lau, Carus H. Y., Flood, Emelie, Hunter, Mark J., Williams-Noonan, Billy J., Corbett, Karen M., Ng, Chai-Ann, Bouwer, James C., Stewart, Alastair G., Perozo, Eduardo, Allen, Toby W., Vandenberg, Jamie I.

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Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmia von Thorpe, Jordan, Perry, Matthew D, Contreras, Osvaldo, Hurley, Emily, Parker, George, Harvey, Richard P, Hill, Adam P, Vandenberg, Jamie I

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Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels von Clarke, Oliver B., Caputo, Alessandro T., Hill, Adam P., Vandenberg, Jamie I., Smith, Brian J., Gulbis, Jacqueline M.

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R222Q SCN5A Mutation Is Associated With Reversible Ventricular Ectopy and Dilated Cardiomyopathy von Mann, Stefan A., PhD, Castro, Maria L., BMedSci(Hons), Ohanian, Monique, BMedSci(Hons), Guo, Guanglan, PhD, Zodgekar, Poonam, MSW, GradDipGenCouns, Sheu, Angela, MB, BS, Stockhammer, Kathryn, BSc, GradDipGenCouns, Thompson, Tina, BNurs, Playford, David, MB, BS, PhD, Subbiah, Rajesh, MB, BS, PhD, Kuchar, Dennis, MD, Aggarwal, Anu, MB, BS, PhD, Vandenberg, Jamie I., MB, BS, PhD, Fatkin, Diane, MD

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Multiple Interactions between Cytoplasmic Domains Regulate Slow Deactivation of Kv11.1 Channels von Ng, Chai Ann, Phan, Kevin, Hill, Adam P., Vandenberg, Jamie I., Perry, Matthew D.

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The diagnostic role of T wave morphology biomarkers in congenital and acquired long QT syndrome: A systematic review von Tardo, Daniel T., Peck, Matthew, Subbiah, Rajesh N., Vandenberg, Jamie I., Hill, Adam. P.

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Reduced connexin-43 expression, slow conduction and repolarisation dispersion in a model of hypertrophic cardiomyopathy von Lim, Seakcheng, Mangala, Melissa M, Holliday, Mira, Cserne Szappanos, Henrietta, Barratt-Ross, Samantha, Li, Serena, Thorpe, Jordan, Liang, Whitney, Ranpura, Ginell N, Vandenberg, Jamie I, Semsarian, Christopher, Hill, Adam P, Hool, Livia C

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Experimentally Validated Pharmacoinformatics Approach to Predict hERG Inhibition Potential of New Chemical Entities von Munawar, Saba, Windley, Monique J, Tse, Edwin G, Todd, Matthew H, Hill, Adam P, Vandenberg, Jamie I, Jabeen, Ishrat

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Drug Binding to the Inactivated State Is Necessary but Not Sufficient for High-Affinity Binding to Human Ether-à-go-go-Related Gene Channels von Perrin, Mark J, Kuchel, Philip W, Campbell, Terence J, Vandenberg, Jamie I

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