Plasma metabolomics and proteomics profiling after a postprandial challenge reveal subtle diet effects on human metabolic status von Pellis, Linette, van Erk, Marjan J., van Ommen, Ben, Bakker, Gertruud C. M., Hendriks, Henk F. J., Cnubben, Nicole H. P., Kleemann, Robert, van Someren, Eugene P., Bobeldijk, Ivana, Rubingh, Carina M., Wopereis, Suzan

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Predicting the therapeutic efficacy of MSC in bone tissue engineering using the molecular marker CADM1 von Mentink, Anouk, Hulsman, Marc, Groen, Nathalie, Licht, Ruud, Dechering, Koen J, van der Stok, Johan, Alves, Hugo A, Dhert, Wouter J, van Someren, Eugene P, Reinders, Marcel J.T, van Blitterswijk, Clemens A, de Boer, Jan

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Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans von Jetten, Marlon J.A., Gaj, Stan, Ruiz-Aracama, Ainhoa, de Kok, Theo M., van Delft, Joost H.M., Lommen, Arjen, van Someren, Eugene P., Jennen, Danyel G.J., Claessen, Sandra M., Peijnenburg, Ad A.C.M., Stierum, Rob H., Kleinjans, Jos C.S.

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DNA methylation restricts spontaneous multi-lineage differentiation of mesenchymal progenitor cells, but is stable during growth factor-induced terminal differentiation von Hupkes, Marlinda, van Someren, Eugene P., Middelkamp, Sjors H.A., Piek, Ester, van Zoelen, Everardus J., Dechering, Koen J.

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Advanced materials earliest assessment (AMEA) von Wohlleben, Wendel, Persson, Michael, Suarez-Merino, Blanca, Baun, Anders, Di Battista, Veronica, Dekkers, Susan, van Someren, Eugene P, Broßell, Dirk, Stahlmecke, Burkhard, Wiemann, Martin, Schmid, Otmar, Haase, Andrea

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Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization von Hulsman, Marc, Mentink, Anouk, van Someren, Eugene P, Dechering, Koen J, de Boer, Jan, Reinders, Marcel Jt

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Epigenetics: DNA demethylation promotes skeletal myotube maturation von Hupkes, Marlinda, Jonsson, Malin K. B., Scheenen, Wim J., Rotterdam, Walter, Sotoca, Ana M., Someren, Eugene P., Heyden, Marcel A. G., Veen, Toon A., Ravestein‐van Os, Roselinde I., Bauerschmidt, Susanne, Piek, Ester, Ypey, Dirk L., Zoelen, Everardus J., Dechering, Koen J.

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Osteo-transcriptomics of human mesenchymal stem cells: Accelerated gene expression and osteoblast differentiation induced by vitamin D reveals c-MYC as an enhancer of BMP2-induced... von Piek, Ester, Sleumer, Laura S, van Someren, Eugene P, Heuver, Leonie, de Haan, Jorn R, de Grijs, Ingrid, Gilissen, Christian, Hendriks, José M, van Ravestein-van Os, Roselinde I, Bauerschmidt, Susanne, Dechering, Koen J, van Zoelen, Everardus J

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Prediction of the Carcinogenic Potential of Human Pharmaceuticals Using Repeated Dose Toxicity Data and Their Pharmacological Properties von van der Laan, Jan Willem, Buitenhuis, Wenny H W, Wagenaar, Laura, Soffers, Ans E M F, van Someren, Eugene P, Krul, Cyrille A M, Woutersen, Ruud A

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Unraveling toxicological mechanisms and predicting toxicity classes with gene dysregulation networks von Pronk, Tessa E., van Someren, Eugene P., Stierum, Rob H., Ezendam, Janine, Pennings, Jeroen L.A.

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Microarray analysis reveals expression regulation of Wnt antagonists in differentiating osteoblasts von Vaes, Bart L.T., Dechering, Koen J., van Someren, Eugene P., Hendriks, José M.A., van de Ven, Cindy J.J.M., Feijen, Alie, Mummery, Christine L., Reinders, Marcel J.T, Olijve, Wiebe, van Zoelen, Everardus J.J., Steegenga, Wilma T.

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Microarray analysis on Runx2-deficient mouse embryos reveals novel Runx2 functions and target genes during intramembranous and endochondral bone formation von Vaes, Bart L.T., Ducy, Patricia, Sijbers, Anneke M., Hendriks, José M.A., van Someren, Eugene P., de Jong, Nanning G., van den Heuvel, Edwin R., Olijve, Wiebe, van Zoelen, Everardus J.J., Dechering, Koen J.

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Integration of Known Transcription Factor Binding Site Information and Gene Expression Data to Advance from Co-Expression to Co-Regulation von Clements, Maarten, van Someren, Eugene P., Knijnenburg, Theo A., Reinders, Marcel J.T.

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Developing computational model-based diagnostics to analyse clinical chemistry data von VAN SCHALKWIJK, Daniël B, VAN BOCHOVE, Kees, VAN OMMEN, Ben, FREIDIG, Andreas P, VAN SOMEREN, Eugene P, VAN DER GREEF, Jan, DE GRAAF, Albert A

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Targettri: A toxicity-based triaging system for novel drug targets von Venhorst, Jennifer, van Someren, Eugene P., van de Brug, Fred J., Kalkman, Gino J., Folkertsma, Simon

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Analysis of HSP90 using a toxicity-based triaging approach for drug targets von Venhorst, Jennifer, van Someren, Eugene P., van de Brug, Fred J., Kalkman, Gino J., Folkertsma, Simon, Krul, Cyrille A.M.

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A holistic approach to the safety assessment of exploratory drug targets von Venhorst, Jennifer, Rankouhi, Tanja Rouhani, Verschuren, Lars, van Someren, Eugene P., Kuper, Frieke C., Wolterbeek, Andre P.M., van de Brug, Fred J., Folkertsma, Simon, Krul, Cyrille A.M.

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Prediction of the Carcinogenic Potential of Human Pharmaceuticals Using Repeated Dose Toxicity Data and Their Pharmacological Properties von van der Laan, Jan Willem, Buitenhuis, Wenny H W, Wagenaar, Laura, Soffers, Ans E M F, van Someren, Eugene P, Krul, Cyrille A M, Woutersen, Ruud A

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Assuring safety without animal testing concept (ASAT). Integration of human disease data with in vitro data to improve toxicology testing von Stierum, Rob, Aarts, Jac, Boorsma, André, Bosgra, Sieto, Caiment, Florian, Ezendam, Janine, Greupink, Rick, Hendriksen, Peter, Soeteman-Hernandez, Lya G., Jennen, Danyel, Kleinjans, Jos, Kroese, Dinant, Kuper, Frieke, van Loveren, Henk, Monshouwer, Mario, Russel, Frans, van Someren, Eugene, Tsamou, Maria, Groothuis, Geny

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