DNA damage and transcription stress cause ATP-mediated redesign of metabolism and potentiation of anti-oxidant buffering von Milanese, Chiara, Bombardieri, Cíntia R., Sepe, Sara, Barnhoorn, Sander, Payán-Goméz, César, Caruso, Donatella, Audano, Matteo, Pedretti, Silvia, Vermeij, Wilbert P., Brandt, Renata M. C., Gyenis, Akos, Wamelink, Mirjam M., de Wit, Annelieke S., Janssens, Roel C., Leen, René, van Kuilenburg, André B. P., Mitro, Nico, Hoeijmakers, Jan H. J., Mastroberardino, Pier G.

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Developments in the treatment of Fabry disease von Veen, Sanne J., Hollak, Carla E. M., Kuilenburg, André B. P., Langeveld, Mirjam

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Retrospective study of long-term outcomes of enzyme replacement therapy in Fabry disease: Analysis of prognostic factors von Arends, Maarten, Biegstraaten, Marieke, Hughes, Derralynn A, Mehta, Atul, Elliott, Perry M, Oder, Daniel, Watkinson, Oliver T, Vaz, Frédéric M, van Kuilenburg, André B P, Wanner, Christoph, Hollak, Carla E M

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Prenatal growth restriction, retinal dystrophy, diabetes insipidus and white matter disease: expanding the spectrum of PRPS1-related disorders von Al-Maawali, Almundher, Dupuis, Lucie, Blaser, Susan, Heon, Elise, Tarnopolsky, Mark, Al-Murshedi, Fathiya, Marshall, Christian R, Paton, Tara, Scherer, Stephen W, Roelofsen, Jeroen, van Kuilenburg, André B P, Mendoza-Londono, Roberto

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Intragenic deletions and a deep intronic mutation affecting pre-mRNA splicing in the dihydropyrimidine dehydrogenase gene as novel mechanisms causing 5-fluorouracil toxicity von van Kuilenburg, André B. P., Meijer, Judith, Mul, Adri N. P. M., Meinsma, Rutger, Schmid, Veronika, Dobritzsch, Doreen, Hennekam, Raoul C. M., Mannens, Marcel M. A. M., Kiechle, Marion, Etienne-Grimaldi, Marie-Christine, Klümpen, Heinz-Josef, Maring, Jan Gerard, Derleyn, Veerle A., Maartense, Ed, Milano, Gérard, Vijzelaar, Raymon, Gross, Eva

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All three MutL complexes are required for repeat expansion in a human stem cell model of CAG-repeat expansion mediated glutaminase deficiency von Hayward, Bruce, Kumari, Daman, Santra, Saikat, van Karnebeek, Clara D. M., van Kuilenburg, André B. P., Usdin, Karen

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Dihydropyrimidine Dehydrogenase Phenotyping Using Pretreatment Uracil: A Note of Caution Based on a Large Prospective Clinical Study von With, Mirjam, Knikman, Jonathan, Man, Femke M., Lunenburg, Carin A. T. C., Henricks, Linda M., Kuilenburg, André B. P., Maring, Jan G., Staveren, Maurice C., Vries, Niels, Rosing, Hilde, Beijnen, Jos H., Pluim, Dick, Modak, Anil, Imholz, Alex L. T., Schaik, Ron H. N., Schellens, Jan H. M., Gelderblom, Hans, Cats, Annemieke, Guchelaar, Henk‐Jan, Mathijssen, Ron H. J., Swen, Jesse J., Meulendijks, Didier

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Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of... von Meulendijks, Didier, PharmD, Henricks, Linda M, PharmD, Sonke, Gabe S, MD, Deenen, Maarten J, PhD, Froehlich, Tanja K, PhD, Amstutz, Ursula, PhD, Largiadèr, Carlo R, Prof, Jennings, Barbara A, PhD, Marinaki, Anthony M, PhD, Sanderson, Jeremy D, MD, Kleibl, Zdenek, PhD, Kleiblova, Petra, PhD, Schwab, Matthias, Prof, Zanger, Ulrich M, Prof, Palles, Claire, PhD, Tomlinson, Ian, Prof, Gross, Eva, PhD, van Kuilenburg, André B P, PhD, Punt, Cornelis J A, Prof, Koopman, Miriam, MD, Beijnen, Jos H, Prof, Cats, Annemieke, MD, Schellens, Jan H M, Prof

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The Cytidine Analog Fluorocyclopentenylcytosine (RX-3117) Is Activated by Uridine-Cytidine Kinase 2 von Sarkisjan, Dzjemma, Julsing, Joris R, Smid, Kees, de Klerk, Daniël, van Kuilenburg, André B P, Meinsma, Rutger, Lee, Young B, Kim, Deog J, Peters, Godefridus J

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Acute Aerobic Exercise Leads to Increased Plasma Levels of R- and S-β-Aminoisobutyric Acid in Humans von Stautemas, Jan, Van Kuilenburg, André B. P., Stroomer, Lida, Vaz, Fred, Blancquaert, Laura, Lefevere, Filip B. D., Everaert, Inge, Derave, Wim

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Optimising urinary catecholamine metabolite diagnostics for neuroblastoma von Matser, Yvette A. H., Verly, Iedan R. N., Ham, Maria, Sain‐van der Velden, Monique G. M., Verhoeven‐Duif, Nanda M., Ash, Shifra, Cangemi, Giuliana, Barco, Sebastiano, Popovic, Maja Beck, Kuilenburg, André B. P., Tytgat, Godelieve A. M., Cañete, Adela, Wieczorek, Aleksandra, Vicha, Ales, Alba, Amparo, Ryan, Anne L, Brichard, Bénédicte, Yalçın, Bilgehan, Martínez, Blanca, Márquez, Catalina, Klapkova, Eva, Schleiermacher, Gudrun, Deubzer, Hedwig, Ryberg, Henrik, Øra, Ingrid, Sastry, Jairam, Bugajska, Jolanta, Gray, Juliet C, Baka, Margarita, Martínez, Maria Luisa, Phillips, Marianne B., Renard, Marleen, Vermeersch, Pieter, Alvaro, Raquel Hladun, Almaraz, Ricardo López, Simon, Thorsten, Ek, Torben, Segura, Vanessa, Papadakis, Vassilios

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Severe phenotype of severe combined immunodeficiency caused by adenosine deaminase deficiency in a patient with a homozygous mutation due to uniparental disomy von Geelen, Joyce, PhD, Pfundt, Rolph, PhD, Meijer, Judith, BASc, Verheijen, Frans W., PhD, van Kuilenburg, Andre B.P., PhD, Warris, Adilia, PhD, Marcelis, Carlo, MD

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Dihydropyrimidine dehydrogenase gene variants for predicting grade 4-5 fluoropyrimidine-induced toxicity: FUSAFE individual patient data meta-analysis von Le Teuff, Gwénaël, Cozic, Nathalie, Boyer, Jean-Christophe, Boige, Valérie, Diasio, Robert B., Taieb, Julien, Meulendijks, Didier, Palles, Claire, Schwab, Matthias, Deenen, Maarten, Largiadèr, Carlo R., Marinaki, Anthony, Jennings, Barbara A., Wettergren, Yvonne, Di Paolo, Antonello, Gross, Eva, Budai, Barna, Ackland, Stephen P., van Kuilenburg, André B. P., McLeod, Howard L., Milano, Gérard, Thomas, Fabienne, Loriot, Marie-Anne, Kerr, David, Schellens, Jan H. M., Laurent-Puig, Pierre, Shi, Qian, Pignon, Jean-Pierre, Etienne-Grimaldi, Marie-Christine

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Hydrogen sulfide donor NaHS reduces organ injury in a rat model of pneumococcal pneumosepsis, associated with improved bio-energetic status von Aslami, Hamid, Pulskens, Wilco P, Kuipers, Maria T, Bos, Aafkeline P, van Kuilenburg, André B P, Wanders, Ronald J A, Roelofsen, Jeroen, Roelofs, Joris J T H, Kerindongo, Raphaela P, Beurskens, Charlotte J P, Schultz, Marcus J, Kulik, Wim, Weber, Nina C, Juffermans, Nicole P

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Liposome-targeted recombinant human acid sphingomyelinase: Production, formulation, and in vitro evaluation von Aldosari, Mohammed H., de Vries, Robert P., Rodriguez, Lucia R., Hesen, Nienke A., Beztsinna, Nataliia, van Kuilenburg, André B.P., Hollak, Carla E.M., Schellekens, Huub, Mastrobattista, Enrico

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Fenretinide induces mitochondrial ROS and inhibits the mitochondrial respiratory chain in neuroblastoma von Cuperus, Roos, Leen, René, Tytgat, Godelieve A. M, Caron, Huib N, van Kuilenburg, André B. P

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Thrombocytopenia after meta-iodobenzylguanidine (MIBG) therapy in neuroblastoma patients may be caused by selective MIBG uptake via the serotonin transporter located on megakaryocy... von Blom, Thomas, Meinsma, Rutger, di Summa, Franca, van den Akker, Emile, van Kuilenburg, André B. P., Hansen, Marten, Tytgat, Godelieve A. M.

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Preemptive screening of DPYD as part of clinical practice: high prevalence of a novel exon 4 deletion in the Finnish population von Saarenheimo, Jatta, Wahid, Nesna, Eigeliene, Natalja, Ravi, Ravichandra, Salomons, Gajja S., Ojeda, Matilde Fernandez, Vijzelaar, Raymon, Jekunen, Antti, van Kuilenburg, André B. P.

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Multi‐omics in classical galactosemia: Evidence for the involvement of multiple metabolic pathways von Hermans, Merel E., Weeghel, Michel, Vaz, Frédéric M., Ferdinandusse, Sacha, Hollak, Carla E. M., Huidekoper, Hidde H., Janssen, Mirian C. H., Kuilenburg, André B. P., Pras‐Raves, Mia L., Wamelink, Mirjam M. C., Wanders, Ronald J. A., Welsink‐Karssies, Mendy M., Bosch, Annet M.

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Multi-OMIC profiling of survival and metabolic signaling networks in cells subjected to photodynamic therapy von Weijer, Ruud, Clavier, Séverine, Zaal, Esther A., Pijls, Maud M. E., van Kooten, Robert T., Vermaas, Klaas, Leen, René, Jongejan, Aldo, Moerland, Perry D., van Kampen, Antoine H. C., van Kuilenburg, André B. P., Berkers, Celia R., Lemeer, Simone, Heger, Michal

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