Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor von Frijters, Raoul, Fleuren, Wilco, Toonen, Erik J M, Tuckermann, Jan P, Reichardt, Holger M, van der Maaden, Hans, van Elsas, Andrea, van Lierop, Marie-Jose, Dokter, Wim, de Vlieg, Jacob, Alkema, Wynand

Volltext

APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment von Tai, Yu-Tzu, Acharya, Chirag, An, Gang, Moschetta, Michele, Zhong, Mike Y., Feng, Xiaoyan, Cea, Michele, Cagnetta, Antonia, Wen, Kenneth, van Eenennaam, Hans, van Elsas, Andrea, Qiu, Lugui, Richardson, Paul, Munshi, Nikhil, Anderson, Kenneth C.

Volltext

Bispecific antibodies targeting dual tumor-associated antigens in cancer therapy von Huang, Shuyu, van Duijnhoven, Sander M. J., Sijts, Alice J. A. M., van Elsas, Andrea

Volltext

Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity von Sivick, Kelsey E., Desbien, Anthony L., Glickman, Laura Hix, Reiner, Gabrielle L., Corrales, Leticia, Surh, Natalie H., Hudson, Thomas E., Vu, Uyen T., Francica, Brian J., Banda, Tamara, Katibah, George E., Kanne, David B., Leong, Justin J., Metchette, Ken, Bruml, Jacob R., Ndubaku, Chudi O., McKenna, Jeffrey M., Feng, Yan, Zheng, Lianxing, Bender, Steven L., Cho, Charles Y., Leong, Meredith L., van Elsas, Andrea, Dubensky, Thomas W., McWhirter, Sarah M.

Volltext

APRIL signaling via TACI mediates immunosuppression by T regulatory cells in multiple myeloma: therapeutic implications von Tai, Yu-Tzu, Lin, Liang, Xing, Lijie, Cho, Shih-Feng, Yu, Tengteng, Acharya, Chirag, Wen, Kenneth, Hsieh, Phillip A., Dulos, John, van Elsas, Andrea, Munshi, Nikhil, Richardson, Paul, Anderson, Kenneth C.

Volltext

CD47–signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction von Zhao, Xi Wen, van Beek, Ellen M, Schornagel, Karin, Van der Maaden, Hans, Van Houdt, Michel, Otten, Marielle A, Finetti, Pascal, Van Egmond, Marjolein, Matozaki, Takashi, Kraal, Georg, Birnbaum, Daniel, van Elsas, Andrea, Kuijpers, Taco W, Bertucci, Francois, van den Berg, Timo K

Volltext

Blockade of ErbB2 and PD-L1 using a bispecific antibody to improve targeted anti-ErbB2 therapy von Mittal, Deepak, Vijayan, Dipti, Neijssen, Joost, Kreijtz, Joost, Habraken, Maurice M. J. M., Van Eenennaam, Hans, Van Elsas, Andrea, Smyth, Mark J.

Volltext

Functional characterization of the selective pan-allele anti-SIRPα antibody ADU-1805 that blocks the SIRPα–CD47 innate immune checkpoint von Voets, Erik, Paradé, Marc, Lutje Hulsik, David, Spijkers, Sanne, Janssen, Wout, Rens, Joost, Reinieren-Beeren, Inge, van den Tillaart, Gilbert, van Duijnhoven, Sander, Driessen, Lilian, Habraken, Maurice, van Zandvoort, Peter, Kreijtz, Joost, Vink, Paul, van Elsas, Andrea, van Eenennaam, Hans

Volltext

Catalytic signature of a heat-stable, chimeric human alkaline phosphatase with therapeutic potential von Kiffer-Moreira, Tina, Sheen, Campbell R, Gasque, Kellen Cristina da Silva, Bolean, Mayte, Ciancaglini, Pietro, van Elsas, Andrea, Hoylaerts, Marc F, Millán, José Luis

Volltext

Biodistribution and translational pharmacokinetic modeling of a human recombinant alkaline phosphatase von Peters, Esther, Stevens, Jasper, Arend, Jacques, Guan, Zheng, Raaben, Willem, Laverman, Peter, Elsas, Andrea van, Masereeuw, Rosalinde, Pickkers, Peter

Volltext

Epitope mapping of monoclonal antibodies: a comprehensive comparison of different technologies von Dang, Xibei, Guelen, Lars, Lutje Hulsik, David, Ermakov, Grigori, Hsieh, Edward J, Kreijtz, Joost, Stammen-Vogelzangs, Judith, Lodewijks, Imke, Bertens, Astrid, Bramer, Arne, Guadagnoli, Marco, Nazabal, Alexis, van Elsas, Andrea, Fischmann, Thierry, Juan, Veronica, Beebe, Amy, Beaumont, Maribel, van Eenennaam, Hans

Volltext

Intratumoral injection of IL-12-encoding mRNA targeted to CSFR1 and PD-L1 exerts potent anti-tumor effects without substantial systemic exposure von Di Trani, Claudia Augusta, Cirella, Assunta, Arrizabalaga, Leire, Alvarez, Maite, Bella, Ángela, Fernandez-Sendin, Myriam, Russo-Cabrera, Joan Salvador, Gomar, Celia, Ardaiz, Nuria, Teijeira, Alvaro, Bolaños, Elixabet, González-Gomariz, José, Otano, Itziar, Aranda, Fernando, Palencia, Belén, Segués, Aina, Huang, Shuyu, van Duijnhoven, Sander M J, van Elsas, Andrea, Melero, Ignacio, Berraondo, Pedro

Volltext

Improvement of the skeletal and dental hypophosphatasia phenotype in Alpl−/− mice by administration of soluble (non-targeted) chimeric alkaline phosphatase von Gasque, Kellen C.S, Foster, Brian L, Kuss, Pia, Yadav, Manisha C, Liu, Jin, Kiffer-Moreira, Tina, van Elsas, Andrea, Hatch, Nan, Somerman, Martha J, Millán, José Luis

Volltext

Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy von Guelen, Lars, Fischmann, Thierry O, Wong, Jerelyn, Mauze, Smita, Guadagnoli, Marco, Bąbała, Nikolina, Wagenaars, Jozef, Juan, Veronica, Rosen, David, Prosise, Winnie, Habraken, Maurice, Lodewijks, Imke, Gu, Danling, Stammen-Vogelzangs, Judith, Yu, Ying, Baker, Jeanne, Lutje Hulsik, David, Driessen-Engels, Lilian, Malashock, Dan, Kreijtz, Joost, Bertens, Astrid, de Vries, Evert, Bovens, Astrid, Bramer, Arne, Zhang, Yiwei, Wnek, Richard, Troth, Sean, Chartash, Elliot, Dobrenkov, Konstantin, Sadekova, Svetlana, van Elsas, Andrea, Cheung, Jason K, Fayadat-Dilman, Laurence, Borst, Jannie, Beebe, Amy M, Van Eenennaam, Hans

Volltext

Shortened Hinge Design of Fab x sdAb-Fc Bispecific Antibodies Enhances Redirected T-Cell Killing of Tumor Cells von Huang, Shuyu, Segués, Aina, Waterfall, Martin, Wright, David, Vayssiere, Charlotte, van Duijnhoven, Sander M J, van Elsas, Andrea, Sijts, Alice J A M, Zaiss, Dietmar M

Volltext

Human Recombinant Alkaline Phosphatase (Ilofotase Alfa) Protects Against Kidney Ischemia-Reperfusion Injury in Mice and Rats Through Adenosine Receptors von Rosin, Diane L, Hall, J Perry, Zheng, Shuqiu, Huang, Liping, Campos-Bilderback, Silvia, Sandoval, Ruben, Bree, Andrea, Beaumont, Kevin, Miller, Emily, Larsen, Jennifer, Hariri, Ghazal, Kaila, Neelu, Encarnacion, Iain M, Gale, Jeremy D, van Elsas, Andrea, Molitoris, Bruce A, Okusa, Mark D

Volltext

bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice von Jansen, Burkhard, Schlagbauer-Wadl, Hermine, Brown, Bob D, Bryan, Robert N, Van Elsas, Andrea, Müller, Markus, Wolff, Klaus, Eichler, Hans-Georg, Pehamberger, Hubert

Volltext

Cancer therapy with antibodies von Paul, Suman, Konig, Maximilian F., Pardoll, Drew M., Bettegowda, Chetan, Papadopoulos, Nickolas, Wright, Katharine M., Gabelli, Sandra B., Ho, Mitchell, van Elsas, Andrea, Zhou, Shibin

Volltext

Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition von Priem, Bram, van Leent, Mandy M.T., Teunissen, Abraham J.P., Sofias, Alexandros Marios, Mourits, Vera P., Willemsen, Lisa, Klein, Emma D., Oosterwijk, Roderick S., Meerwaldt, Anu E., Munitz, Jazz, Prévot, Geoffrey, Vera Verschuur, Anna, Nauta, Sheqouia A., van Leeuwen, Esther M., Fisher, Elizabeth L., de Jong, Karen A.M., Zhao, Yiming, Toner, Yohana C., Soultanidis, Georgios, Calcagno, Claudia, Bomans, Paul H.H., Friedrich, Heiner, Sommerdijk, Nico, Reiner, Thomas, Duivenvoorden, Raphaël, Zupančič, Eva, Di Martino, Julie S., Kluza, Ewelina, Rashidian, Mohammad, Ploegh, Hidde L., Dijkhuizen, Rick M., Hak, Sjoerd, Pérez-Medina, Carlos, Bravo-Cordero, Jose Javier, de Winther, Menno P.J., Joosten, Leo A.B., van Elsas, Andrea, Fayad, Zahi A., Rialdi, Alexander, Torre, Denis, Guccione, Ernesto, Ochando, Jordi, Netea, Mihai G., Griffioen, Arjan W., Mulder, Willem J.M.

Volltext

Integrated Single-Cell (Phospho-)Protein and RNA Detection Uncovers Phenotypic Characteristics and Active Signal Transduction of Human Antibody-Secreting Cells von van Buijtenen, Erik, Janssen, Wout, Vink, Paul, Habraken, Maurice J.M., Wingens, Laura J.A., van Elsas, Andrea, Huck, Wilhelm T.S., van Buggenum, Jessie A.G.L., van Eenennaam, Hans

Volltext