Structural and time‐resolved mechanistic investigations of protein hydrolysis by the acidic proline‐specific endoprotease from Aspergillus niger von Pijning, Tjaard, Vujičić‐Žagar, Andreja, Laan, Jan‐Metske, Jong, René M., Ramirez‐Palacios, Carlos, Vente, Andre, Edens, Luppo, Dijkstra, Bauke W.

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Directed Evolution Strategies for Enantiocomplementary Haloalkane Dehalogenases: From Chemical Waste to Enantiopure Building Blocks von van Leeuwen, Jan G. E., Wijma, Hein J., Floor, Robert J., van der Laan, Jan-Metske, Janssen, Dick B.

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Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum von McLean, Kirsty J, Hans, Marcus, Meijrink, Ben, van Scheppingen, Wibo B, Vollebregt, Aad, Tee, Kang Lan, van der Laan, Jan-Metske, Leys, David, Munro, Andrew W, van den Berg, Marco A

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Optical simulation of monolithic scintillator detectors using GATE/GEANT4 von van der Laan, D J (Jan), Schaart, Dennis R, Maas, Marnix C, Beekman, Freek J, Bruyndonckx, Peter, van Eijk, Carel W E

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Response to 'Statins accelerate the onset of collagen type II-induced arthritis in mice'-authors' reply von Vandebriel, Rob J, De Jong, Hilda J I, Gremmer, Eric R, Klungel, Olaf H, Tervaert, Jan-Willem Cohen, Slob, Wout, Van Der Laan, Jan W, Van Loveren, Henk

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Limits on the spatial resolution of monolithic scintillators read out by APD arrays von van der Laan, D J (Jan), Maas, Marnix C, Bruyndonckx, Peter, Schaart, Dennis R

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The RETHINK project on minipigs in the toxicity testing of new medicines and chemicals: Conclusions and recommendations von Forster, Roy, Bode, Gerd, Ellegaard, Lars, van der Laan, Jan-Willem

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reclin2: a Toolkit for Record Linkage and Deduplication von Jan van der Laan, D.

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Monolithic scintillator PET detectors with intrinsic depth-of-interaction correction von Maas, Marnix C, Schaart, Dennis R, van der Laan, D J (Jan), Bruyndonckx, Peter, Lemaître, Cedric, Beekman, Freek J, van Eijk, Carel W E

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Editorial: Reducing animal use in carcinogenicity testing von Van der Laan, Jan Willem, Manuppello, Joseph

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Revision of ICH S8 Needed? von Van Der Laan, Jan Willem

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Structures of an Isopenicillin N Converting Ntn-Hydrolase Reveal Different Catalytic Roles for the Active Site Residues of Precursor and Mature Enzyme von Bokhove, Marcel, Yoshida, Hiromi, Hensgens, Charles M.H., Metske van der Laan, Jan, Sutherland, John D., Dijkstra, Bauke W.

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A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicals von Luijten, Mirjam, Corvi, Raffaella, Mehta, Jyotigna, Corvaro, Marco, Delrue, Nathalie, Felter, Susan, Haas, Bodo, Hewitt, Nicola J., Hilton, Gina, Holmes, Thomas, Jacobs, Miriam N., Jacobs, Abigail, Lamplmair, Franz, Lewis, Dick, Madia, Federica, Manou, Irene, Melching-Kollmuss, Stephanie, Schorsch, Frederic, Schütte, Katrin, Sewell, Fiona, Strupp, Christian, van der Laan, Jan Willem, Wolf, Douglas C., Wolterink, Gerrit, Woutersen, Ruud, Zvonar, Zvonimir, Heusinkveld, Harm, Braakhuis, Hedwig

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Insulin-like growth factor 1 receptor activation promotes mammary gland tumor development by increasing glycolysis and promoting biomass production von Ter Braak, Bas, Siezen, Christine L, Lee, Joo S, Rao, Pooja, Voorhoeve, Charlotte, Ruppin, Eytan, van der Laan, Jan Willem, van de Water, Bob

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Regulatory acceptability of the minipig in the development of pharmaceuticals, chemicals and other products von van der Laan, Jan Willem, Brightwell, John, McAnulty, Peter, Ratky, Joszef, Stark, Claudia

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Nonclinical regulatory immunotoxicity testing of nanomedicinal products: Proposed strategy and possible pitfalls von Giannakou, Christina, Park, Margriet V. D. Z., Bosselaers, Irene E. M., Jong, Wim H., Laan, Jan Willem, Loveren, Henk, Vandebriel, Rob J., Geertsma, Robert E.

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Treatment with insulin (analogues) and breast cancer risk in diabetics; a systematic review and meta-analysis of in vitro, animal and human evidence von Bronsveld, Heleen K, ter Braak, Bas, Karlstad, Øystein, Vestergaard, Peter, Starup-Linde, Jakob, Bazelier, Marloes T, De Bruin, Marie L, de Boer, Anthonius, Siezen, Christine L E, van de Water, Bob, van der Laan, Jan Willem, Schmidt, Marjanka K

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Towards a continuous crystal APD-based PET detector design von Bruyndonckx, Peter, Lemaître, Cedric, Schaart, Dennis, Maas, Marnix, van der Laan, D.J. (jan), Krieguer, Magalie, Devroede, Olivier, Tavernier, Stefaan

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Alternative signaling network activation through different insulin receptor family members caused by pro-mitogenic antidiabetic insulin analogues in human mammary epithelial cells von ter Braak, Bas, Wink, Steven, Koedoot, Esmee, Pont, Chantal, Siezen, Christine, van der Laan, Jan Willem, van de Water, Bob

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ICH S1 prospective evaluation study: weight of evidence approach to predict outcome and value of 2-year rat carcinogenicity studies. A report from the regulatory authorities subgro... von Bourcier, Todd, McGovern, Timothy, Cavaliero, Tania, Ebere, Geoffrey, Nishikawa, Akiyoshi, Nishimura, Jihei, Ogawa, Kumiko, Pasanen, Markku, Vespa, Alisa, Van der Laan, Jan Willem

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