Lipophilicity and biomimetic properties measured by HPLC to support drug discovery von Valkó, Klára L.

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Estimating Unbound Volume of Distribution and Tissue Binding by In Vitro HPLC-Based Human Serum Albumin and Immobilised Artificial Membrane-Binding Measurements von Valkó, Klára L., Nunhuck, Shenaz B., Hill, Alan P.

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Biomimetic chromatography—A novel application of the chromatographic principles von Valko, Klara L

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2,5-Diketopiperazines as Potent, Selective, and Orally Bioavailable Oxytocin Antagonists. 3. Synthesis, Pharmacokinetics, and in Vivo Potency von Borthwick, Alan D, Davies, Dave E, Exall, Anne M, Hatley, Richard J. D, Hughes, Jennifer A, Irving, Wendy R, Livermore, David G, Sollis, Steve L, Nerozzi, Fabrizio, Valko, Klara L, Allen, Michael J, Perren, Marion, Shabbir, Shalia S, Woollard, Patrick M, Price, Mark A

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Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzothiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitors von Tedesco, Rosanna, Chai, Deping, Darcy, Michael G., Dhanak, Dashyant, Fitch, Duke M., Gates, Adam, Johnston, Victor K., Keenan, Richard M., Lin-Goerke, Juili, Sarisky, Robert T., Shaw, Antony N., Valko, Klara L., Wiggall, Kenneth J., Zimmerman, Michael N., Duffy, Kevin J.

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Biomimetic properties and estimated in vivo distribution of chloroquine and hydroxy-chloroquine enantiomers von Valko, Klara L, Zhang, Tong

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Application of biomimetic HPLC to estimate in vivo behavior of early drug discovery compounds von Valko, Klara L

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Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzo-thiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitor... von TEDESCO, Rosanna, DEPING CHAI, SHAW, Antony N, VALKO, Klara L, WIGGALL, Kenneth J, ZIMMERMAN, Michael N, DUFFY, Kevin J, DARCY, Michael G, DHANAK, Dashyant, FITCH, Duke M, GATES, Adam, JOHNSTON, Victor K, KEENAN, Richard M, LIN-GOERKE, Juili, SARISKY, Robert T

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Improving the passive permeability of macrocyclic peptides: Balancing permeability with other physicochemical properties von Thansandote, Praew, Harris, Robert M., Dexter, Hannah L., Simpson, Graham L., Pal, Sandeep, Upton, Richard J., Valko, Klara

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Retention in reversed-phase liquid chromatography as a function of mobile-phase composition von Valkó, Klara, Snyder, Lloyd R., Glajch, Joseph L.

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A comparative study of the reversed-phase HPLC retention behaviour of S-adenosyl- l-methionine and its related metabolites on Hypersil ODS and Supelcosil™ LC-ABZ stationary phases... von Valkó, Klára, Hamedani, Morteza P., Ascah, Tracy L., Gibbons, William A.

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