Evaluation and Reduction of CRISPR Off-Target Cleavage Events von Vakulskas, Christopher A., Behlke, Mark A.

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Global role of the bacterial post-transcriptional regulator CsrA revealed by integrated transcriptomics von Potts, Anastasia H., Vakulskas, Christopher A., Pannuri, Archana, Yakhnin, Helen, Babitzke, Paul, Romeo, Tony

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Identification of preexisting adaptive immunity to Cas9 proteins in humans von Charlesworth, Carsten T., Deshpande, Priyanka S., Dever, Daniel P., Camarena, Joab, Lemgart, Viktor T., Cromer, M. Kyle, Vakulskas, Christopher A., Collingwood, Michael A., Zhang, Liyang, Bode, Nicole M., Behlke, Mark A., Dejene, Beruh, Cieniewicz, Brandon, Romano, Rosa, Lesch, Benjamin J., Gomez-Ospina, Natalia, Mantri, Sruthi, Pavel-Dinu, Mara, Weinberg, Kenneth I., Porteus, Matthew H.

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A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells von Vakulskas, Christopher A., Dever, Daniel P., Rettig, Garrett R., Turk, Rolf, Jacobi, Ashley M., Collingwood, Michael A., Bode, Nicole M., McNeill, Matthew S., Yan, Shuqi, Camarena, Joab, Lee, Ciaran M., Park, So Hyun, Wiebking, Volker, Bak, Rasmus O., Gomez-Ospina, Natalia, Pavel-Dinu, Mara, Sun, Wenchao, Bao, Gang, Porteus, Matthew H., Behlke, Mark A.

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Boosting genome editing efficiency in human cells and plants with novel LbCas12a variants von Zhang, Liyang, Li, Gen, Zhang, Yingxiao, Cheng, Yanhao, Roberts, Nathaniel, Glenn, Steve E, DeZwaan-McCabe, Diane, Rube, H Tomas, Manthey, Jeff, Coleman, Gary, Vakulskas, Christopher A, Qi, Yiping

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Generation of the transgene-free canker-resistant Citrus sinensis using Cas12a/crRNA ribonucleoprotein in the T0 generation von Su, Hang, Wang, Yuanchun, Xu, Jin, Omar, Ahmad A., Grosser, Jude W., Calovic, Milica, Zhang, Liyang, Feng, Yu, Vakulskas, Christopher A., Wang, Nian

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Antagonistic control of the turnover pathway for the global regulatory sRNA CsrB by the CsrA and CsrD proteins von Vakulskas, Christopher A, Leng, Yuanyuan, Abe, Hazuki, Amaki, Takumi, Okayama, Akihiro, Babitzke, Paul, Suzuki, Kazushi, Romeo, Tony

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CsrA activates flhDC expression by protecting flhDC mRNA from RNase E‐mediated cleavage von Yakhnin, Alexander V., Baker, Carol S., Vakulskas, Christopher A., Yakhnin, Helen, Berezin, Igor, Romeo, Tony, Babitzke, Paul

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Genomic Targets and Features of BarA-UvrY (-SirA) Signal Transduction Systems von Zere, Tesfalem R, Vakulskas, Christopher A, Leng, Yuanyuan, Pannuri, Archana, Potts, Anastasia H, Dias, Raquel, Tang, Dongjie, Kolaczkowski, Bryan, Georgellis, Dimitris, Ahmer, Brian M M, Romeo, Tony

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Amount of Cas9 protein introduced into mouse embryos via electroporation affects the genome-editing rate von WAKE, Yui, VAKULSKAS, Christopher A., GLENN, Steve E., KANEKO, Takehito

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Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells von Baik, Ron, Cromer, M. Kyle, Glenn, Steve E., Vakulskas, Christopher A., Chmielewski, Kay O., Dudek, Amanda M., Feist, William N., Klermund, Julia, Shipp, Suzette, Cathomen, Toni, Dever, Daniel P., Porteus, Matthew H.

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Post-transcriptional regulation on a global scale: form and function of Csr/Rsm systems von Romeo, Tony, Vakulskas, Christopher A., Babitzke, Paul

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Highly Efficient Genome Editing in Plant Protoplasts by Ribonucleoprotein Delivery of CRISPR-Cas12a Nucleases von Zhang, Yingxiao, Cheng, Yanhao, Fang, Hong, Roberts, Nathaniel, Zhang, Liyang, Vakulskas, Christopher A, Niedz, Randall P, Culver, James N, Qi, Yiping

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Translational Repression of NhaR, a Novel Pathway for Multi-Tier Regulation of Biofilm Circuitry by CsrA von PANNURI, Archana, YAKHNIN, Helen, VAKULSKAS, Christopher A, EDWARDS, Adrianne N, BABITZKE, Paul, ROMEO, Tony

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Efficiency, Specificity and Temperature Sensitivity of Cas9 and Cas12a RNPs for DNA-free Genome Editing in Plants von Banakar, Raviraj, Schubert, Mollie, Kurgan, Gavin, Rai, Krishan Mohan, Beaudoin, Sarah F, Collingwood, Michael A, Vakulskas, Christopher A, Wang, Kan, Zhang, Feng

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ExsD Inhibits Expression of the Pseudomonas aeruginosa Type III Secretion System by Disrupting ExsA Self-Association and DNA Binding Activity von BRUTINEL, Evan D, VAKULSKAS, Christopher A, YAHR, Timothy L

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Regulation of bacterial virulence by Csr (Rsm) systems von Vakulskas, Christopher A, Potts, Anastasia H, Babitzke, Paul, Ahmer, Brian M M, Romeo, Tony

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Efficient Targeted Mutagenesis Mediated by CRISPR-Cas12a Ribonucleoprotein Complexes in Maize von Dong, Shujie, Qin, Yinping Lucy, Vakulskas, Christopher A., Collingwood, Michael A., Marand, Mariam, Rigoulot, Stephen, Zhu, Ling, Jiang, Yaping, Gu, Weining, Fan, Chunyang, Mangum, Anna, Chen, Zhongying, Yarnall, Michele, Zhong, Heng, Elumalai, Sivamani, Shi, Liang, Que, Qiudeng

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Functional Domains of ExsA, the Transcriptional Activator of the Pseudomonas aeruginosa Type III Secretion System von BRUTINEL, Evan D, VAKULSKAS, Christopher A, YAHR, Timothy L

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Mechanism of Transcriptional Activation by Pseudomonas aeruginosa ExsA von VAKULSKAS, Christopher A, BRADY, Keith M, YAHR, Timothy L

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