Chemical Proteomics and Phenotypic Profiling Identifies the Aryl Hydrocarbon Receptor as a Molecular Target of the Utrophin Modulator Ezutromid von Wilkinson, Isabel V. L., Perkins, Kelly J., Dugdale, Hannah, Moir, Lee, Vuorinen, Aini, Chatzopoulou, Maria, Squire, Sarah E., Monecke, Sebastian, Lomow, Alexander, Geese, Marcus, Charles, Philip D., Burch, Peter, Tinsley, Jonathan M., Wynne, Graham M., Davies, Stephen G., Wilson, Francis X., Rastinejad, Fraydoon, Mohammed, Shabaz, Davies, Kay E., Russell, Angela J.

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Isolation, Structural Identification, Synthesis, and Pharmacological Profiling of 1,2-trans-Dihydro-1,2-diol Metabolites of the Utrophin Modulator Ezutromid von Chatzopoulou, Maria, Claridge, Tim D. W, Davies, Kay E, Davies, Stephen G, Elsey, David J, Emer, Enrico, Fletcher, Ai M, Harriman, Shawn, Robinson, Neil, Rowley, Jessica A, Russell, Angela J, Tinsley, Jonathon M, Weaver, Richard, Wilkinson, Isabel V. L, Willis, Nicky J, Wilson, Francis X, Wynne, Graham M

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Functionalised Cofactor Mimics for Interactome Discovery and Beyond von Wilkinson, Isabel V. L., Pfanzelt, Martin, Sieber, Stephan A.

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Profiling the Heme‐Binding Proteomes of Bacteria Using Chemical Proteomics von Wilkinson, Isabel V. L., Bottlinger, Max, El Harraoui, Yassmine, Sieber, Stephan A.

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Combining experimental strategies for successful target deconvolution von Wilkinson, Isabel V.L., Terstappen, Georg C., Russell, Angela J.

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From diagnosis to therapy in Duchenne muscular dystrophy von Babbs, Arran, Chatzopoulou, Maria, Edwards, Ben, Squire, Sarah E, Wilkinson, Isabel V L, Wynne, Graham M, Russell, Angela J, Davies, Kay E

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Treatment with homodimeric interleukin-12 (IL-12) p40 protects mice from IL-12-dependent shock but not from tumor necrosis factor alpha-dependent shock von MATTNER, F, OZMEN, L, PODLASKI, F. J, WILKINSON, V. L, PRESKY, D. H, GATELY, M. K, ALBER, G

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The Cyanobacterial “Nutraceutical” Phycocyanobilin Inhibits Cysteine Protease Legumain von Wilkinson, Isabel V. L., Castro‐Falcón, Gabriel, Roda‐Serrat, Maria C., Purdy, Trevor N., Straetener, Jan, Brauny, Melanie M., Maier, Lisa, Brötz‐Oesterhelt, Heike, Christensen, Lars P., Sieber, Stephan A., Hughes, Chambers C.

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Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy von Vuorinen, Aini, Wilkinson, Isabel V.L., Chatzopoulou, Maria, Edwards, Ben, Squire, Sarah E., Fairclough, Rebecca J., Bazan, Noelia Araujo, Milner, Josh A., Conole, Daniel, Donald, James R., Shah, Nandini, Willis, Nicky J., Martínez, R. Fernando, Wilson, Francis X., Wynne, Graham M., Davies, Stephen G., Davies, Kay E., Russell, Angela J.

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Aminothiazolones as potent, selective and cell active inhibitors of the PIM kinase family von Quevedo, Camilo E., Bataille, Carole J.R., Byrne, Simon, Durbin, Matthew, Elkins, Jon, Guillermo, Abigail, Jones, Alan M., Knapp, Stefan, Nadali, Anna, Walker, Roderick G., Wilkinson, Isabel V.L., Wynne, Graham M., Davies, Stephen G., Russell, Angela J.

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Untersuchung des Häm‐bindenden bakteriellen Proteoms mittels chemischer Proteomik von Wilkinson, Isabel V. L., Bottlinger, Max, El Harraoui, Yassmine, Sieber, Stephan A.

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Characterisation of utrophin modulator SMT C1100 as a non-competitive inhibitor of firefly luciferase von Wilkinson, Isabel V.L., Reynolds, Jessica K., Galan, Sébastien R.G., Vuorinen, Aini, Sills, Adam J., Pires, Elisabete, Wynne, Graham M., Wilson, Francis X., Russell, Angela J.

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A tubulin binding molecule drives differentiation of acute myeloid leukemia cells von Jackson, Thomas R., Vuorinen, Aini, Josa-Culleré, Laia, Madden, Katrina S., Conole, Daniel, Cogswell, Thomas J., Wilkinson, Isabel V.L., Kettyle, Laura M., Zhang, Douzi, O’Mahony, Alison, Gracias, Deanne, McCall, Lorna, Westwood, Robert, Terstappen, Georg C., Davies, Stephen G., Tate, Edward W., Wynne, Graham M., Vyas, Paresh, Russell, Angela J., Milne, Thomas A.

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Down-regulation of the pharmacokinetic-pharmacodynamic response to interleukin-12 during long-term administration to patients with renal cell carcinoma and evaluation of the mechan... von Rakhit, Ashok, Yeon, Mitchell M., Ferrante, Jessica, Fettner, Scott, Nadeau, Rosemary, Motzer, Robert, Bukowski, Ronald, Carvajal, Daisy M., Wilkinson, Victoria L., Presky, David H., Magram, Jeanne, Gately, Maurice K.

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Consensus repeat domains of E-selectin enhance ligand binding von S H Li, D K Burns, J M Rumberger, D H Presky, V L Wilkinson, M Anostario, Jr, B A Wolitzky, C R Norton, P C Familletti, K J Kim

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Funktionalisierte Cofaktor‐Analoga für die Erforschung von Interaktomen und darüber hinaus von Wilkinson, Isabel V. L., Pfanzelt, Martin, Sieber, Stephan A.

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Chemical Proteomics and Phenotypic Profiling Identifies the Aryl Hydrocarbon Receptor as a Molecular Target of the Utrophin Modulator Ezutromid von Wilkinson, Isabel V. L., Perkins, Kelly J., Dugdale, Hannah, Moir, Lee, Vuorinen, Aini, Chatzopoulou, Maria, Squire, Sarah E., Monecke, Sebastian, Lomow, Alexander, Geese, Marcus, Charles, Philip D., Burch, Peter, Tinsley, Jonathan M., Wynne, Graham M., Davies, Stephen G., Wilson, Francis X., Rastinejad, Fraydoon, Mohammed, Shabaz, Davies, Kay E., Russell, Angela J.

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Cloning and characterization of a mouse IL-12 receptor-beta component von Chua, AO, Wilkinson, VL, Presky, DH, Gubler, U

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Characterization of anti-mouse IL-12 monoclonal antibodies and measurement of mouse IL-12 by ELISA von Wilkinson, Victoria L., Warrier, Rajeev R., Truitt, Theresa P., Nunes, Perla, Gately, Maurice K., Presky, David H.

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Interleukin-12 Antagonist Activity of Mouse Interleukin-12 p40 Homodimer in Vitro and in Vivo von GATELY, MAURICE K., CARVAJAL, DAISY M., CONNAUGHTON, SUZANNE E., GILLESSEN, SILKE, WARRIER, RAJEEV R., KOLINSKY, KENNETH D., WILKINSON, VICTORIA L., DWYER, CYNTHIA M., HIGGINS JR, GEORGE F., PODLASKI, FRANK J., FAHERTY, DENISE A., FAMILLETTI, PHILIP C., STERN, ALVIN S., PRESKY, DAVID H.

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