Morphine Pharmacodynamics in Mechanically Ventilated Preterm Neonates Undergoing Endotracheal Suctioning von Välitalo, P. A., Krekels, E. H. J., van Dijk, M., Simons, S. H. P., Tibboel, D., Knibbe, C. A. J.

Volltext

Semiphysiologically based pharmacokinetic model for midazolam and CYP3A mediated metabolite 1‐OH‐midazolam in morbidly obese and weight loss surgery patients von Brill, MJE, Välitalo, PAJ, Darwich, AS, van Ramshorst, B, van Dongen, HPA, Rostami–Hodjegan, A, Danhof, M, Knibbe, CAJ

Volltext

Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen von van Rongen, Anne, Välitalo, Pyry A. J., Peeters, Mariska Y. M., Boerma, Djamila, Huisman, Fokko W., van Ramshorst, Bert, van Dongen, Eric P. A., van den Anker, Johannes N., Knibbe, Catherijne A. J.

Volltext

When will the Glomerular Filtration Rate in Former Preterm Neonates Catch up with Their Term Peers? von Wu, Yunjiao, Allegaert, Karel, Flint, Robert B., Goulooze, Sebastiaan C., Välitalo, Pyry A. J., de Hoog, Matthijs, Mulla, Hussain, Sherwin, Catherine M. T., Simons, Sinno H. P., Krekels, Elke H. J., Knibbe, Catherijne A. J., Völler, Swantje

Volltext

Towards Rational Dosing Algorithms for Vancomycin in Neonates and Infants Based on Population Pharmacokinetic Modeling von Janssen, Esther J H, Välitalo, Pyry A J, Allegaert, Karel, de Cock, Roosmarijn F W, Simons, Sinno H P, Sherwin, Catherine M T, Mouton, Johan W, van den Anker, Johannes N, Knibbe, Catherijne A J

Volltext

Influence of Morbid Obesity on the Pharmacokinetics of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide von de Hoogd, Sjoerd, Välitalo, Pyry A. J., Dahan, Albert, van Kralingen, Simone, Coughtrie, Michael M. W., van Dongen, Eric P. A., van Ramshorst, Bert, Knibbe, Catherijne A. J.

Volltext

Central nervous system penetration of oxycodone after intravenous and epidural administration von Kokki, M., Välitalo, P., Kuusisto, M., Ranta, V.P., Raatikainen, K., Hautajärvi, H., Kokki, H.

Volltext

Higher Midazolam Clearance in Obese Adolescents Compared with Morbidly Obese Adults von van Rongen, Anne, Brill, Margreke J. E., Vaughns, Janelle D., Välitalo, Pyry A. J., van Dongen, Eric P. A., van Ramshorst, Bert, Barrett, Jeffrey S., van den Anker, Johannes N., Knibbe, Catherijne A. J.

Volltext

Morphine Glucuronidation and Elimination in Intensive Care Patients: A Comparison with Healthy Volunteers von Ahlers, Sabine J. G. M, Välitalo, Pyry A. J., Peeters, Mariska Y. M., Gulik, Laura van, van Dongen, Eric P. A., Dahan, Albert, Tibboel, Dick, Knibbe, Catherijne A. J.

Volltext

Predicting Unacceptable Pain in Cardiac Surgery Patients Receiving Morphine Maintenance and Rescue Doses: A Model-Based Pharmacokinetic-Pharmacodynamic Analysis von Goulooze, Sebastiaan C., Krekels, Elke H., Saleh, Mohammed A., Ahlers, Sabine J., Välitalo, Pyry A., van Dongen, Eric P., van Schaik, Ron H., Hankemeier, Thomas, Tibboel, Dick, Knibbe, Catherijne A. J.

Volltext

Pain and distress caused by endotracheal suctioning in neonates is better quantified by behavioural than physiological items: a comparison based on item response theory modelling von Välitalo, Pyry A.J., van Dijk, Monique, Krekels, Elke H.J., Gibbins, Sharyn, Simons, Sinno H.P., Tibboel, Dick, Knibbe, Catherijne A.J.

Volltext

Maturation of Oxycodone Pharmacokinetics in Neonates and Infants: a Population Pharmacokinetic Model of Three Clinical Trials von Välitalo, Pyry, Kokki, Merja, Ranta, Veli-Pekka, Olkkola, Klaus T., Hooker, Andrew C., Kokki, Hannu

Volltext

Population pharmacometrics in support of analgesics studies von VÄLITALO, P., RANTA, V.-P., HOOKER, A. C., KOKKI, M., KOKKI, H.

Volltext

Novel model-based dosing guidelines for gentamicin and tobramycin in preterm and term neonates von Valitalo, Pyry A J, van den Anker, John N, Allegaert, Karel, de Cock, Roosmarijn F W, de Hoog, Matthijs, Simons, Sinno H P, Mouton, Johan W, Knibbe, Catherijne A J

Volltext

Population pharmacometrics in support of analgesics studies: Fundamentals of population pharmacometrics von VÄLITALO, P., RANTA, V.-P., HOOKER, A. C., KOKKI, M., KOKKI, H.

Volltext

Pharmacokinetics of oxycodone in infants: 9AP6-8 von Kokki, H., Kokki, M., Välitalo, P., Pitkänen, H., Tolonen, A., Ranta, V. -P.

Volltext

Epidural administration of oxycodone: 9AP6-9 von Kokki, M., Välitalo, P., Kuusisto, M., Ranta, V. -P., Tolonen, A., Kokki, H.

Volltext

S152 IMPAIRED CLEARANCE AND UNALTERED BIOAVAILABILITY OF THREE ORAL OXYCODONE FORMULATIONS IN ELDERLY PATIENTS von Kokki, M., Välitalo, P., Rasanen, I., Aaltomaa, S., Nordman, H., Ojanperä, I., Eskelinen, M., Kokki, H.

Volltext

Physiologically based modelling framework for prediction of pulmonary pharmacokinetics of antimicrobial target site concentrations von Aulin, L.B.S., Tandar, S.T., Zijp, T. van, Ballegooie, E. van, Graaf, P.H. van der, Saleh, M.A.A.E.W., Välitalo, P., Hasselt, J.G.C. van

Volltext bestellen

Children in clinical trials: towards evidence-based pediatric pharmacotherapy using pharmacokinetic-pharmacodynamic modeling von Brussee, J, Calvier, E, Krekels, E, Valitalo, P, Tibboel, D, Allegaert, Karel, Knibbe, C

Volltext