Mechanism-Based Inactivation of Human Cytochromes P450s: Experimental Characterization, Reactive Intermediates, and Clinical Implications von Hollenberg, Paul F, Kent, Ute M, Bumpus, Namandjé N

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The inactivation of human CYP2E1 by phenethyl isothiocyanate, a naturally occurring chemopreventive agent, and its oxidative bioactivation von Yoshigae, Yasushi, Sridar, Chitra, Kent, Ute M, Hollenberg, Paul F

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Role of the Highly Conserved Threonine in Cytochrome P450 2E1: Prevention of H2O2‑Induced Inactivation during Electron Transfer von Yoshigae, Yasushi, Kent, Ute M, Hollenberg, Paul F

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Mechanistic Analysis of the Inactivation of Cytochrome P450 2B6 by Phencyclidine: Effects on Substrate Binding, Electron Transfer, and Uncoupling von Shebley, Mohamad, Kent, Ute M., Ballou, David P., Hollenberg, Paul F.

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Inactivation of Cytochrome P450 2B1 by Benzyl Isothiocyanate, a Chemopreventative Agent from Cruciferous Vegetables von Goosen, Theunis C, Kent, Ute M, Brand, Linda, Hollenberg, Paul F

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Modification of Serine 360 by a Reactive Intermediate of 17-a-Ethynylestradiol Results in Mechanism-Based Inactivation of Cytochrome P450s 2B1 and 2B6 von Kent, Ute M, Sridar, Chitra, Spahlinger, Greg, Hollenberg, Paul F

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Modification of Serine 360 by a Reactive Intermediate of 17-α-Ethynylestradiol Results in Mechanism-Based Inactivation of Cytochrome P450s 2B1 and 2B6 von Kent, Ute M, Sridar, Chitra, Spahlinger, Greg, Hollenberg, Paul F

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Inactivation of Cytochrome P450 2E1 by Benzyl Isothiocyanate von Moreno, Rosa L, Kent, Ute M, Hodge, Kimberly, Hollenberg, Paul F

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Mutation of Tyrosine 190 to Alanine Eliminates the Inactivation of Cytochrome P450 2B1 by Peroxynitrite von Lin, Hsia-lien, Kent, Ute M, Zhang, Haoming, Waskell, Lucy, Hollenberg, Paul F

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Identification of 17-α-Ethynylestradiol-Modified Active Site Peptides and Glutathione Conjugates Formed during Metabolism and Inactivation of P450s 2B1 and 2B6 von Kent, Ute M, Lin, Hsia-lien, Mills, Danielle E, Regal, Kelly A, Hollenberg, Paul F

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Dynamics of Signal Transduction after Aggregation of Cell-Surface Receptors: Studies on the Type I Receptor for IgE von KENT, U. M, SU-YAU MAO, WOFSY, C, GOLDSTEIN, B, ROSS, S, METZGER, H

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Mechanism-Based Inactivation of Cytochromes P450 2E1 and 2E1 T303A by tert-Butyl Acetylenes:  Characterization of Reactive Intermediate Adducts to the Heme and Apoprotein von Blobaum, Anna L, Kent, Ute M, Alworth, William L, Hollenberg, Paul F

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Formation of a Novel Reversible Cytochrome P450 Spectral Intermediate:  Role of Threonine 303 in P450 2E1 Inactivation von Blobaum, Anna L, Lu, Yipin, Kent, Ute M, Wang, Shaomeng, Hollenberg, Paul F

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Mechanism-Based Inactivation of Cytochrome P450 2B1 by 7-Ethynylcoumarin:  Verification of Apo-P450 Adduction by Electrospray Ion Trap Mass Spectrometry von Regal, Kelly A, Schrag, Michael L, Kent, Ute M, Wienkers, Larry C, Hollenberg, Paul F

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Microsomal cytochromes P450 catalyze the oxidation of low density lipoprotein von Aviram, Michael, Kent, Ute M., Hollenberg, Paul F.

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Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphe... von Kent, Ute M, Pascual, Lise, Roof, Rebecca A, Ballou, David P, Hollenberg, Paul F

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Role of the Highly Conserved Threonine in Cytochrome P450 2E1: Prevention of H 2 O 2 -Induced Inactivation during Electron Transfer von Yoshigae, Yasushi, Kent, Ute M., Hollenberg, Paul F.

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Mechanism-Based Inactivation of Cytochromes P450 2B1 and P450 2B6 by n-Propylxanthate von Kent, Ute M, Yanev, Stanislav, Hollenberg, Paul F

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Alteration of the heme prosthetic group of neuronal nitric-oxide synthase during inactivation by N(G)-amino-L-arginine in vitro and in vivo von Vuletich, Jennifer L, Lowe, Ezra R, Jianmongkol, Suree, Kamada, Yasuhiko, Kent, Ute M, Bender, Andrew T, Demady, Damon R, Hollenberg, Paul F, Osawa, Yoichi

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Spectral Studies of tert-Butyl Isothiocyanate-Inactivated P450 2E1 von Kent, Ute M, Roberts-Kirchhoff, Elizabeth S, Moon, Namdoo, Dunham, William R, Hollenberg, Paul F

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