Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function von Takata, Kazuyuki, Kozaki, Tatsuya, Lee, Christopher Zhe Wei, Thion, Morgane Sonia, Otsuka, Masayuki, Lim, Shawn, Utami, Kagistia Hana, Fidan, Kerem, Park, Dong Shin, Malleret, Benoit, Chakarov, Svetoslav, See, Peter, Low, Donovan, Low, Gillian, Garcia-Miralles, Marta, Zeng, Ruizhu, Zhang, Jinqiu, Goh, Chi Ching, Gul, Ahmet, Hubert, Sandra, Lee, Bernett, Chen, Jinmiao, Low, Ivy, Shadan, Nurhidaya Binte, Lum, Josephine, Wei, Tay Seok, Mok, Esther, Kawanishi, Shohei, Kitamura, Yoshihisa, Larbi, Anis, Poidinger, Michael, Renia, Laurent, Ng, Lai Guan, Wolf, Yochai, Jung, Steffen, Önder, Tamer, Newell, Evan, Huber, Tara, Ashihara, Eishi, Garel, Sonia, Pouladi, Mahmoud A., Ginhoux, Florent

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Reversal of Phenotypic Abnormalities by CRISPR/Cas9-Mediated Gene Correction in Huntington Disease Patient-Derived Induced Pluripotent Stem Cells von Xu, Xiaohong, Tay, Yilin, Sim, Bernice, Yoon, Su-In, Huang, Yihui, Ooi, Jolene, Utami, Kagistia Hana, Ziaei, Amin, Ng, Bryan, Radulescu, Carola, Low, Donovan, Ng, Alvin Yu Jin, Loh, Marie, Venkatesh, Byrappa, Ginhoux, Florent, Augustine, George J., Pouladi, Mahmoud A.

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Urokinase plasminogen activator mediates changes in human astrocytes modeling fragile X syndrome von Peteri, Ulla‐Kaisa, Pitkonen, Juho, Toma, Ilario, Nieminen, Otso, Utami, Kagistia Hana, Strandin, Tomas M., Corcoran, Padraic, Roybon, Laurent, Vaheri, Antti, Ethell, Iryna, Casarotto, Plinio, Pouladi, Mahmoud A., Castrén, Maija L.

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A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability von Chia, Poh Hui, Zhong, Franklin Lei, Niwa, Shinsuke, Bonnard, Carine, Utami, Kagistia Hana, Zeng, Ruizhu, Lee, Hane, Eskin, Ascia, Nelson, Stanley F, Xie, William H, Al-Tawalbeh, Samah, El-Khateeb, Mohammad, Shboul, Mohammad, Pouladi, Mahmoud A, Al-Raqad, Mohammed, Reversade, Bruno

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Maturation Delay of Human GABAergic Neurogenesis in Fragile X Syndrome Pluripotent Stem Cells von Zhang, Ai, Sokolova, Irina, Domissy, Alain, Davis, Joshua, Rao, Lee, Hana Utami, Kagistia, Wang, Yanling, Hagerman, Randi J, Pouladi, Mahmoud A, Sanna, Pietro, Boland, Michael J, Loring, Jeanne F

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Elevated de novo protein synthesis in FMRP-deficient human neurons and its correction by metformin treatment von Utami, Kagistia Hana, Yusof, Nur Amirah Binte Mohammad, Kwa, Jing Eugene, Peteri, Ulla-Kaisa, Castrén, Maija L, Pouladi, Mahmoud A

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A Micropatterned Human‐Specific Neuroepithelial Tissue for Modeling Gene and Drug‐Induced Neurodevelopmental Defects von Sahni, Geetika, Chang, Shu‐Yung, Meng, Jeremy Teo Choon, Tan, Jerome Zu Yao, Fatien, Jean Jacques Clement, Bonnard, Carine, Utami, Kagistia Hana, Chan, Puck Wee, Tan, Thong Teck, Altunoglu, Umut, Kayserili, Hülya, Pouladi, Mahmoud, Reversade, Bruno, Toh, Yi‐Chin

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Generation of the Human Pluripotent Stem-Cell-Derived Astrocyte Model with Forebrain Identity von Peteri, Ulla-Kaisa, Pitkonen, Juho, Utami, Kagistia Hana, Paavola, Jere, Roybon, Laurent, Pouladi, Mahmoud A, Castrén, Maija L

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A Micropatterned Human‐Specific Neuroepithelial Tissue for Modeling Gene and Drug‐Induced Neurodevelopmental Defects von Sahni, Geetika, Chang, Shu‐Yung, Teo, Jeremy Choon Meng, Tan, Jerome Zu Yao, Fatien, Jean Jacques Clement, Bonnard, Carine, Utami, Kagistia Hana, Chan, Puck Wee, Tan, Thong Teck, Altunoglu, Umut, Kayserili, Hülya, Pouladi, Mahmoud, Reversade, Bruno, Toh, Yi‐Chin

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MicroRNAs: a symphony orchestrating evolution and disease dynamics von Quah, Shan, Subramanian, Gowtham, Tan, Jonathan S.L., Utami, Kagistia Hana, Sampath, Prabha

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iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer von Park, Dong Shin, Kozaki, Tatsuya, Tiwari, Satish Kumar, Moreira, Marco, Khalilnezhad, Ahad, Torta, Federico, Olivié, Nicolas, Thiam, Chung Hwee, Liani, Oniko, Silvin, Aymeric, Phoo, Wint Wint, Gao, Liang, Triebl, Alexander, Tham, Wai Kin, Gonçalves, Leticia, Kong, Wan Ting, Raman, Sethi, Zhang, Xiao Meng, Dunsmore, Garett, Dutertre, Charles Antoine, Lee, Salanne, Ong, Jia Min, Balachander, Akhila, Khalilnezhad, Shabnam, Lum, Josephine, Duan, Kaibo, Lim, Ze Ming, Tan, Leonard, Low, Ivy, Utami, Kagistia Hana, Yeo, Xin Yi, Di Tommaso, Sylvaine, Dupuy, Jean-William, Varga, Balazs, Karadottir, Ragnhildur Thora, Madathummal, Mufeeda Changaramvally, Bonne, Isabelle, Malleret, Benoit, Binte, Zainab Yasin, Wei Da, Ngan, Tan, Yingrou, Wong, Wei Jie, Zhang, Jinqiu, Chen, Jinmiao, Sobota, Radoslaw M., Howland, Shanshan W., Ng, Lai Guan, Saltel, Frédéric, Castel, David, Grill, Jacques, Minard, Veronique, Albani, Salvatore, Chan, Jerry K. Y., Thion, Morgane Sonia, Jung, Sang Yong, Wenk, Markus R., Pouladi, Mahmoud A., Pasqualini, Claudia, Angeli, Veronique, Cexus, Olivier N. F., Ginhoux, Florent

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Swift induction of human spinal lower motor neurons and robust ALS cell screening via single-cell imaging von Setsu, Selena, Morimoto, Satoru, Nakamura, Shiho, Ozawa, Fumiko, Utami, Kagistia Hana, Nishiyama, Ayumi, Suzuki, Naoki, Aoki, Masashi, Takeshita, Yukio, Tomari, Yukihide, Okano, Hideyuki

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Integrative Analysis Identifies Key Molecular Signatures Underlying Neurodevelopmental Deficits in Fragile X Syndrome von Utami, Kagistia Hana, Skotte, Niels H., Colaço, Ana R., Yusof, Nur Amirah Binte Mohammad, Sim, Bernice, Yeo, Xin Yi, Bae, Han-Gyu, Garcia-Miralles, Marta, Radulescu, Carola I., Chen, Qiyu, Chaldaiopoulou, Georgia, Liany, Herty, Nama, Srikanth, Peteri, Ulla-Kaisa A., Sampath, Prabha, Castrén, Maija L., Jung, Sangyong, Mann, Matthias, Pouladi, Mahmoud A.

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Dysregulated COMT Expression in Fragile X Syndrome von Utami, Kagistia Hana, Yusof, Nur Amirah Binte Muhammed, Garcia-Miralles, Marta, Skotte, Niels Henning, Nama, Srikanth, Sampath, Prabha, Langley, Sarah R., Pouladi, Mahmoud A.

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Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy von Hengel, Holger, Bosso-Lefèvre, Célia, Grady, George, Szenker-Ravi, Emmanuelle, Li, Hankun, Pierce, Sarah, Lebigot, Élise, Tan, Thong-Teck, Eio, Michelle Y., Narayanan, Gunaseelan, Utami, Kagistia Hana, Yau, Monica, Handal, Nader, Deigendesch, Werner, Keimer, Reinhard, Marzouqa, Hiyam M., Gunay-Aygun, Meral, Muriello, Michael J., Verhelst, Helene, Weckhuysen, Sarah, Mahida, Sonal, Naidu, Sakkubai, Thomas, Terrence G., Lim, Jiin Ying, Tan, Ee Shien, Haye, Damien, Willemsen, Michèl A. A. P., Oegema, Renske, Mitchell, Wendy G., Pierson, Tyler Mark, Andrews, Marisa V., Willing, Marcia C., Rodan, Lance H., Barakat, Tahsin Stefan, van Slegtenhorst, Marjon, Gavrilova, Ralitza H., Martinelli, Diego, Gilboa, Tal, Tamim, Abdullah M., Hashem, Mais O., AlSayed, Moeenaldeen D., Abdulrahim, Maha M., Al-Owain, Mohammed, Awaji, Ali, Mahmoud, Adel A. H., Faqeih, Eissa A., Asmari, Ali Al, Algain, Sulwan M., Jad, Lamyaa A., Aldhalaan, Hesham M., Helbig, Ingo, Koolen, David A., Riess, Angelika, Kraegeloh-Mann, Ingeborg, Bauer, Peter, Gulsuner, Suleyman, Stamberger, Hannah, Ng, Alvin Yu Jin, Tang, Sha, Tohari, Sumanty, Keren, Boris, Schultz-Rogers, Laura E., Klee, Eric W., Barresi, Sabina, Tartaglia, Marco, Mor-Shaked, Hagar, Maddirevula, Sateesh, Begtrup, Amber, Telegrafi, Aida, Pfundt, Rolph, Schüle, Rebecca, Ciruna, Brian, Bonnard, Carine, Pouladi, Mahmoud A., Stewart, James C., Claridge-Chang, Adam, Lefeber, Dirk J., Alkuraya, Fowzan S., Mathuru, Ajay S., Venkatesh, Byrappa, Barycki, Joseph J., Simpson, Melanie A., Jamuar, Saumya S., Schöls, Ludger, Reversade, Bruno

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B14 Mapping cell type-specific protein interactomes of huntingtin by live biotin ligase tagging: a proof-of-concept study in human neural progenitor cells von Utami, Kagistia Hana, Meng Qi, Bernice Sim, Sobota, Radoslaw M, Pouladi, Mahmoud A

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Widespread dysregulation of mRNA splicing implicates RNA processing in the development and progression of Huntington's diseaseResearch in context von Vincent Tano, Kagistia Hana Utami, Nur Amirah Binte Mohammad Yusof, Jocelyn Bégin, Willy Wei Li Tan, Mahmoud A. Pouladi, Sarah R. Langley

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Widespread dysregulation of mRNA splicing implicates RNA processing in the development and progression of Huntington's disease von Tano, Vincent, Utami, Kagistia Hana, Yusof, Nur Amirah Binte Mohammad, Bégin, Jocelyn, Tan, Willy Wei Li, Pouladi, Mahmoud A., Langley, Sarah R.

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Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function von Takata, Kazuyuki, Kozaki, Tatsuya, Lee, Christopher Zhe Wei, Thion, Morgane Sonia, Otsuka, Masayuki, Lim, Shawn, Utami, Kagistia Hana, Fidan, Kerem, Park, Dong Shin, Malleret, Benoit, Chakarov, Svetoslav, See, Peter, Low, Donovan, Low, Gillian, Garcia-Miralles, Marta, Zeng, Ruizhu, Zhang, Jinqiu, Goh, Chi Ching, Gul, Ahmet, Hubert, Sandra, Lee, Bernett, Chen, Jinmiao, Low, Ivy, Shadan, Nurhidaya Binte, Lum, Josephine, Wei, Tay Seok, Mok, Esther, Kawanishi, Shohei, Kitamura, Yoshihisa, Larbi, Anis, Poidinger, Michael, Renia, Laurent, Ng, Lai Guan, Wolf, Yochai, Jung, Steffen, Önder, Tamer, Newell, Evan, Huber, Tara, Ashihara, Eishi, Garel, Sonia, Pouladi, Mahmoud A., Ginhoux, Florent

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Impaired Development of Neural-Crest Cell-Derived Organs and Intellectual Disability Caused by MED13L Haploinsufficiency von Utami, Kagistia Hana, Winata, Cecilia Lanny, Hillmer, Axel M., Aksoy, Irene, Long, Hoang Truong, Liany, Herty, Chew, Elaine G. Y., Mathavan, Sinnakaruppan, Tay, Stacey K. H., Korzh, Vladimir, Sarda, Pierre, Davila, Sonia, Cacheux, Valere

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