Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers von Brouwer, Jason M., Westphal, Dana, Dewson, Grant, Robin, Adeline Y., Uren, Rachel T., Bartolo, Ray, Thompson, Geoff V., Colman, Peter M., Kluck, Ruth M., Czabotar, Peter E.

Volltext

The BCL‐2 family member BID plays a role during embryonic development in addition to its BH3‐only protein function by acting in parallel to BAX, BAK and BOK von Ke, Francine S, Holloway, Steven, Uren, Rachel T, Wong, Agnes W, Little, Melissa H, Kluck, Ruth M, Voss, Anne K, Strasser, Andreas

Volltext

Disordered clusters of Bak dimers rupture mitochondria during apoptosis von Uren, Rachel T, O'Hely, Martin, Iyer, Sweta, Bartolo, Ray, Shi, Melissa X, Brouwer, Jason M, Alsop, Amber E, Dewson, Grant, Kluck, Ruth M

Volltext

NAb-seq: an accurate, rapid, and cost-effective method for antibody long-read sequencing in hybridoma cell lines and single B cells von Subas Satish, Hema Preethi, Zeglinski, Kathleen, Uren, Rachel T., Nutt, Stephen L., Ritchie, Matthew E., Gouil, Quentin, Kluck, Ruth M.

Volltext

Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins von Uren, Rachel T, Croning, Mike D R, Fernández, Esperanza, Armstrong, J Douglas, Kopanitsa, Maksym V, Choudhary, Jyoti S, Collins, Mark O, Zografos, Lysimachos, Grant, Seth G N, Komiyama, Noboru H

Volltext

Regulation of neurotrophin receptor (Trk) signaling: suppressor of cytokine signaling 2 (SOCS2) is a new player von Uren, Rachel T, Turnley, Ann M

Volltext

Pore formation by dimeric Bak and Bax: an unusual pore? von Uren, Rachel T., Iyer, Sweta, Kluck, Ruth M.

Volltext

Probing BAK and BAX Activation and Pore Assembly with Cytochrome c Release, Limited Proteolysis, and Oxidant-Induced Linkage von Iyer, Sweta, Uren, Rachel T., Kluck, Ruth M.

Volltext

Structure of detergent-activated BAK dimers derived from the inert monomer von Birkinshaw, Richard W., Iyer, Sweta, Lio, Daisy, Luo, Cindy S., Brouwer, Jason M., Miller, Michelle S., Robin, Adeline Y., Uren, Rachel T., Dewson, Grant, Kluck, Ruth M., Colman, Peter M., Czabotar, Peter E.

Volltext

A novel inhibitory BAK antibody enables assessment of non-activated BAK in cancer cells von Subas Satish, Hema Preethi, Iyer, Sweta, Shi, Melissa X., Wong, Agnes W., Fischer, Karla C., Wardak, Ahmad Z., Lio, Daisy, Brouwer, Jason M., Uren, Rachel T., Czabotar, Peter E., Miller, Michelle S., Kluck, Ruth M.

Volltext

Avoiding adsorption of Bcl-2 proteins to plasticware is important for accurate quantitation von Hockings, Colin, Iyer, Sweta, Uren, Rachel T., Kluck, Ruth M.

Volltext

SOCS-6 Binds to Insulin Receptor Substrate 4, and Mice Lacking the SOCS-6 Gene Exhibit Mild Growth Retardation von Krebs, Danielle L., Uren, Rachel T., Metcalf, Donald, Rakar, Steven, Zhang, Jian-Guo, Starr, Robyn, De Souza, David P., Hanzinikolas, Kathy, Eyles, Jo, Connolly, Lisa M., Simpson, Richard J., Nicola, Nicos A., Nicholson, Sandra E., Baca, Manuel, Hilton, Douglas J., Alexander, Warren S.

Volltext

Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids von Miller, Michelle S., Cowan, Angus D., Brouwer, Jason M., Smyth, Sean T., Peng, Liuyu, Wardak, Ahmad Z., Uren, Rachel T., Luo, Cindy, Roy, Michael J., Shah, Sayali, Tan, Ziwen, Reid, Gavin E., Colman, Peter M., Czabotar, Peter E.

Volltext

Robust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target von Iyer, Sweta, Uren, Rachel T., Dengler, Michael A., Shi, Melissa X., Uno, Etsuko, Adams, Jerry M., Dewson, Grant, Kluck, Ruth M.

Volltext

Mitochondrial Permeabilization Relies on BH3 Ligands Engaging Multiple Prosurvival Bcl-2 Relatives, Not Bak von Uren, Rachel T., Dewson, Grant, Chen, Lin, Coyne, Stephanie C., Huang, David C. S., Adams, Jerry M., Kluck, Ruth M.

Volltext

Neurotransmitters drive combinatorial multistate postsynaptic density networks von Coba, Marcelo P, Pocklington, Andrew J, Collins, Mark O, Kopanitsa, Maksym V, Uren, Rachel T, Swamy, Sajani, Croning, Mike D R, Choudhary, Jyoti S, Grant, Seth G N

Volltext

Mitochondrial release of pro-apoptotic proteins: electrostatic interactions can hold cytochrome c but not Smac/DIABLO to mitochondrial membranes von Uren, Rachel T, Dewson, Grant, Bonzon, Christine, Lithgow, Trevor, Newmeyer, Donald D, Kluck, Ruth M

Volltext

A novel role of suppressor of cytokine signaling‐2 in the regulation of TrkA neurotrophin receptor biology von Uren, Rachel T., Turbić, Alisa, Wong, Agnes W., Klein, Reuben, Murray, Simon S., Turnley, Ann M.

Volltext

Pore formation by dimeric Bak and Bax: an unusual pore? von Uren, Rachel T., Iyer, Sweta, Kluck, Ruth M.

Volltext

Mitochondrial Release of Pro-apoptotic Proteins von Uren, Rachel T., Dewson, Grant, Bonzon, Christine, Lithgow, Trevor, Newmeyer, Donald D., Kluck, Ruth M.

Volltext