Structural studies of Chikungunya virus maturation von Yap, Moh Lan, Klose, Thomas, Urakami, Akane, Hasan, S. Saif, Akahata, Wataru, Rossmann, Michael G.

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Small GTPase R-Ras Regulates Integrity and Functionality of Tumor Blood Vessels von Sawada, Junko, Urakami, Takeo, Li, Fangfei, Urakami, Akane, Zhu, Weiquan, Fukuda, Minoru, Li, Dean Y., Ruoslahti, Erkki, Komatsu, Masanobu

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An Envelope-Modified Tetravalent Dengue Virus-Like-Particle Vaccine Has Implications for Flavivirus Vaccine Design von Urakami, Akane, Ngwe Tun, Mya Myat, Moi, Meng Ling, Sakurai, Atsuko, Ishikawa, Momoko, Kuno, Sachiko, Ueno, Ryuji, Morita, Kouichi, Akahata, Wataru

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315 iPSC-derived CAR-iNKT cells targeting HER2 show prolonged tumor control and promote durable survival in a tumor xenograft model von Urakami, Akane, Shioya, Koichiro, Shigeura, Tomokuni, Matsumura, Tomio, Mishima, Yuji, Okoshi, Momoko, Koseki, Haruhiko, Zhang, Lilin

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A tetravalent dengue virus-like particle vaccine induces high levels of neutralizing antibodies and reduces dengue replication in non-human primates von Thoresen, Daniel, Matsuda, Kenta, Urakami, Akane, Ngwe Tun, Mya Myat, Nomura, Takushi, Moi, Meng Ling, Watanabe, Yuri, Ishikawa, Momoko, Hau, Trang Thi Thu, Yamamoto, Hiroyuki, Suzaki, Yuriko, Ami, Yasushi, Smith, Jonathan F, Matano, Tetsuro, Morita, Kouichi, Akahata, Wataru

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Development of a Novel Virus-Like Particle Vaccine Platform That Mimics the Immature Form of Alphavirus von Urakami, Akane, Sakurai, Atsuko, Ishikawa, Momoko, Yap, Moh Lan, Flores-Garcia, Yevel, Haseda, Yasunari, Aoshi, Taiki, Zavala, Fidel P, Rossmann, Michael G, Kuno, Sachiko, Ueno, Ryuji, Akahata, Wataru

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Abstract 2307: Small GTPase R-Ras promotes normalization of tumor vasculature: a potential oxygen-sensing independent mechanism von Komatsu, Masanobu, Sawada, Junko, Urakami, Takeo, Li, Fangfei, Urakami, Akane

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Driver gene alterations and activated signaling pathways toward malignant progression of gastrointestinal stromal tumors von Ohshima, Keiichi, Fujiya, Keiichi, Nagashima, Takeshi, Ohnami, Sumiko, Hatakeyama, Keiichi, Urakami, Kenichi, Naruoka, Akane, Watanabe, Yuko, Moromizato, Sachi, Shimoda, Yuji, Ohnami, Shumpei, Serizawa, Masakuni, Akiyama, Yasuto, Kusuhara, Masatoshi, Mochizuki, Tohru, Sugino, Takashi, Shiomi, Akio, Tsubosa, Yasuhiro, Uesaka, Katsuhiko, Terashima, Masanori, Yamaguchi, Ken

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BMP4 and PHLDA1 are plausible drug-targetable candidate genes for KRAS G12A-, G12D-, and G12V-driven colorectal cancer von Ohnami, Shumpei, Maruyama, Kouji, Chen, Kai, Takahashi, Yu, Hatakeyama, Keiichi, Ohshima, Keiichi, Shimoda, Yuji, Sakai, Ai, Kamada, Fukumi, Nakatani, Sou, Naruoka, Akane, Ohnami, Sumiko, Kusuhara, Masatoshi, Akiyama, Yasuto, Kagawa, Hiroyasu, Shiomi, Akio, Nagashima, Takeshi, Urakami, Kenichi, Yamaguchi, Ken

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Japanese version of The Cancer Genome Atlas, JCGA, established using fresh frozen tumors obtained from 5143 cancer patients von Nagashima, Takeshi, Yamaguchi, Ken, Urakami, Kenichi, Shimoda, Yuji, Ohnami, Sumiko, Ohshima, Keiichi, Tanabe, Tomoe, Naruoka, Akane, Kamada, Fukumi, Serizawa, Masakuni, Hatakeyama, Keiichi, Matsumura, Kenya, Ohnami, Shumpei, Maruyama, Koji, Mochizuki, Tohru, Kusuhara, Masatoshi, Shiomi, Akio, Ohde, Yasuhisa, Terashima, Masanori, Uesaka, Katsuhiko, Onitsuka, Tetsuro, Nishimura, Seiichiro, Hirashima, Yasuyuki, Hayashi, Nakamasa, Kiyohara, Yoshio, Tsubosa, Yasuhiro, Katagiri, Hirohisa, Niwakawa, Masashi, Takahashi, Kaoru, Kashiwagi, Hiroya, Nakagawa, Masahiro, Ishida, Yuji, Sugino, Takashi, Takahashi, Mitsuru, Akiyama, Yasuto

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Mutational burden and signatures in 4000 Japanese cancers provide insights into tumorigenesis and response to therapy von Hatakeyama, Keiichi, Nagashima, Takeshi, Ohshima, Keiichi, Ohnami, Sumiko, Ohnami, Shumpei, Shimoda, Yuji, Serizawa, Masakuni, Maruyama, Koji, Naruoka, Akane, Akiyama, Yasuto, Urakami, Kenichi, Kusuhara, Masatoshi, Mochizuki, Tohru, Yamaguchi, Ken

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Tumor cell enrichment by tissue suspension improves sensitivity to copy number variation in diffuse gastric cancer with low tumor content von Hatakeyama, Keiichi, Muramatsu, Koji, Nagashima, Takeshi, Ichida, Hiroyuki, Kawanishi, Yuichi, Fukumura, Ryutaro, Ohshima, Keiichi, Shimoda, Yuji, Ohnami, Sumiko, Ohnami, Shumpei, Maruyama, Koji, Naruoka, Akane, Kenmotsu, Hirotsugu, Urakami, Kenichi, Akiyama, Yasuto, Sugino, Takashi, Yamaguchi, Ken

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Characterization of tumors with ultralow tumor mutational burden in Japanese cancer patients von Hatakeyama, Keiichi, Nagashima, Takeshi, Ohshima, Keiichi, Ohnami, Sumiko, Ohnami, Shumpei, Shimoda, Yuji, Naruoka, Akane, Maruyama, Koji, Iizuka, Akira, Ashizawa, Tadashi, Mochizuki, Tohru, Urakami, Kenichi, Akiyama, Yasuto, Yamaguchi, Ken

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Tumor mutational burden analysis of 2,000 Japanese cancer genomes using whole exome and targeted gene panel sequencing von HATAKEYAMA, Keiichi, NAGASHIMA, Takeshi, URAKAMI, Kenichi, OHSHIMA, Keiichi, SERIZAWA, Masakuni, OHNAMI, Sumiko, SHIMODA, Yuji, OHNAMI, Shumpei, MARUYAMA, Koji, NARUOKA, Akane, AKIYAMA, Yasuto, KUSUHARA, Masatoshi, MOCHIZUKI, Tohru, YAMAGUCHI, Ken

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JCGA: the Japanese version of the Cancer Genome Atlas and its contribution to the interpretation of gene alterations detected in clinical cancer genome sequencing von Serizawa, Masakuni, Mizuguchi, Maki, Urakami, Kenichi, Nagashima, Takeshi, Ohshima, Keiichi, Hatakeyama, Keiichi, Ohnami, Sumiko, Ohnami, Shumpei, Maruyama, Koji, Ashizawa, Tadashi, Iizuka, Akira, Horiuchi, Yasue, Naruoka, Akane, Kenmotsu, Hirotsugu, Akiyama, Yasuto, Yamaguchi, Ken

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Evaluation of whole genome sequencing utility in identifying driver alterations in cancer genome von Nagashima, Takeshi, Yamaguchi, Ken, Urakami, Kenichi, Shimoda, Yuji, Ohnami, Sumiko, Ohshima, Keiichi, Tanabe, Tomoe, Naruoka, Akane, Kamada, Fukumi, Serizawa, Masakuni, Hatakeyama, Keiichi, Ohnami, Shumpei, Maruyama, Koji, Mochizuki, Tohru, Mizuguchi, Maki, Shiomi, Akio, Ohde, Yasuhisa, Bando, Etsuro, Sugiura, Teiichi, Mukaigawa, Takashi, Nishimura, Seiichiro, Hirashima, Yasuyuki, Mitsuya, Koichi, Yoshikawa, Shusuke, Kiyohara, Yoshio, Tsubosa, Yasuhiro, Katagiri, Hirohisa, Niwakawa, Masashi, Takahashi, Kaoru, Kashiwagi, Hiroya, Yasunaga, Yoshichika, Ishida, Yuji, Sugino, Takashi, Kenmotsu, Hirotsugu, Terashima, Masanori, Takahashi, Mitsuru, Uesaka, Katsuhiko, Akiyama, Yasuto

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Comparison of genetic susceptibility to lung adenocarcinoma and squamous cell carcinoma in Japanese patients using a novel panel for cancer-related drug-metabolizing enzyme genes von Ohnami, Sumiko, Naruoka, Akane, Isaka, Mitsuhiro, Mizuguchi, Maki, Nakatani, Sou, Kamada, Fukumi, Shimoda, Yuji, Sakai, Ai, Ohshima, Keiichi, Hatakeyama, Keiichi, Maruyama, Kouji, Ohde, Yasuhisa, Kenmotsu, Hirotsugu, Takahashi, Toshiaki, Akiyama, Yasuto, Nagashima, Takeshi, Urakami, Kenichi, Ohnami, Shumpei, Yamaguchi, Ken

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Mutational concordance analysis provides supportive information for double cancer diagnosis von Hatakeyama, Keiichi, Nagashima, Takeshi, Notsu, Akifumi, Ohshima, Keiichi, Ohnami, Sumiko, Ohnami, Shumpei, Shimoda, Yuji, Naruoka, Akane, Maruyama, Koji, Iizuka, Akira, Ashizawa, Tadashi, Kenmotsu, Hirotsugu, Mochizuki, Tohru, Urakami, Kenichi, Akiyama, Yasuto, Yamaguchi, Ken

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Impact of somatic mutations and transcriptomic alterations on cancer aneuploidy von HATAKEYAMA, Keiichi, NAGASHIMA, Takeshi, OHSHIMA, Keiichi, OHNAMI, Sumiko, OHNAMI, Shumpei, SHIMODA, Yuji, NARUOKA, Akane, MARUYAMA, Koji, IIZUKA, Akira, ASHIZAWA, Tadashi, KENMOTSU, Hirotsugu, MOCHIZUKI, Tohru, URAKAMI, Kenichi, AKIYAMA, Yasuto, YAMAGUCHI, Ken

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Next generation sequencing approach for detecting 491 fusion genes from human cancer von URAKAMI, Kenichi, SHIMODA, Yuji, OHSHIMA, Keiichi, NAGASHIMA, Takeshi, SERIZAWA, Masakuni, TANABE, Tomoe, SAITO, Junko, USUI, Tamiko, WATANABE, Yuko, NARUOKA, Akane, OHNAMI, Sumiko, OHNAMI, Shumpei, MOCHIZUKI, Tohru, KUSUHARA, Masatoshi, YAMAGUCHI, Ken

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