Discovery of novel thieno[2,3- d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: Synthesis, biological evaluation, and structure–activity relationships von Horiuchi, Takao, Chiba, Jun, Uoto, Kouichi, Soga, Tsunehiko

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Discovery of Novel Thieno[2,3-d]pyrimidin-4-yl Hydrazone-Based Cyclin-Dependent Kinase 4 Inhibitors: Synthesis, Biological Evaluation and Structure–Activity Relationships von Horiuchi, Takao, Takeda, Yasuyuki, Haginoya, Noriyasu, Miyazaki, Masaki, Nagata, Motoko, Kitagawa, Mayumi, Akahane, Kouichi, Uoto, Kouichi

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Discovery of DS-5272 as a promising candidate: A potent and orally active p53–MDM2 interaction inhibitor von Miyazaki, Masaki, Uoto, Kouichi, Sugimoto, Yuuichi, Naito, Hiroyuki, Yoshida, Keisuke, Okayama, Tooru, Kawato, Haruko, Miyazaki, Masaya, Kitagawa, Mayumi, Seki, Takahiko, Fukutake, Setsuko, Aonuma, Masashi, Soga, Tsunehiko

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Inhibition of ergosterol synthesis by novel antifungal compounds targeting C-14 reductase von Hata, Masato, Ishii, Yoshikazu, Watanabe, Eri, Uoto, Kouichi, Kobayashi, Shozo, Yoshida, Ken-Ichi, Otani, Tsuyoshi, Ando, Akikazu

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A New Water‐soluble Camptothecin Derivative, DX‐8951f, Exhibits Potent Antitumor Activity against Human Tumors in vitro and in vivo von Mitsui, Ikuo, Kumazawa, Eiji, Hirota, Yasuhide, Aonuma, Masashi, Sugimori, Masamichi, Ohsuki, Satoru, Uoto, Kouichi, Ejima, Akio, Terasawa, Hirofumi, Sato, Keiki

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Design, synthesis, and optimization of a series of 2-azaspiro[3.3]heptane derivatives as orally bioavailable fetal hemoglobin inducers von Katayama, Katsushi, Tsunemi, Tomoyuki, Miyazaki, Kazuo, Uoto, Kouichi, Yoshioka, Ryosuke, Terashima, Hideki, Terakawa, Maki, Yamashiro, Kyoko, Haruyama, Munetada, Maeda, Hiroaki, Makino, Tomohiro

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Design, synthesis, and biological activity of piperidine diamine derivatives as factor Xa inhibitor von Mochizuki, Akiyoshi, Nakamoto, Yumi, Naito, Hiroyuki, Uoto, Kouichi, Ohta, Toshiharu

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Synthesis and Structure-Activity Relationships of Novel 2', 2'-Difluoro Analogues of Docetaxel von UOTO, Kouichi, OHSUKI, Satoru, TAKENOSHITA, Haruhiro, ISHIYAMA, Takashi, IIMURA, Shin, HIROTA, Yasuhide, MITSUI, Ikuo, TERASAWA, Hirofumi, SOGA, Tsunehiko

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Discovery of novel thieno[2,3- d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: Synthesis, biological evaluation and structure–activity relationships. Part 2 von Horiuchi, Takao, Nagata, Motoko, Kitagawa, Mayumi, Akahane, Kouichi, Uoto, Kouichi

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A New Method for Synthesis of 7-Deoxytaxane Analogues by Hydrogenation of Δ6,7-Taxane Derivatives von Takeda, Yasuyuki, Yoshino, Toshiharu, Uoto, Kouichi, Terasawa, Hirofumi, Soga, Tsunehiko

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Synthesis and Evaluation of Water-Soluble Non-Prodrug Analogs of Docetaxel Bearing sec-Aminoethyl Group at the C-10 Position von UOTO, Kouichi, TAKENOSHITA, Haruhiro, YOSHINO, Toshiharu, HIROTA, Yasuhide, ANDO, Shuichi, MITSUI, Ikuo, TERASAWA, Hirofumi, SOGA, Tsunehiko

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Design, synthesis and SAR of novel ethylenediamine and phenylenediamine derivatives as factor Xa inhibitors von Yoshikawa, Kenji, Yoshino, Toshiharu, Yokomizo, Yoshihiro, Uoto, Kouichi, Naito, Hiroyuki, Kawakami, Katsuhiro, Mochizuki, Akiyoshi, Nagata, Tsutomu, Suzuki, Makoto, Kanno, Hideyuki, Takemura, Makoto, Ohta, Toshiharu

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Discovery of Novel Thieno[2,3-d]pyrimidin-4-yl Hydrazone-Based Cyclin-Dependent Kinase 4 Inhibitors von Horiuchi, Takao, Takeda, Yasuyuki, Haginoya, Noriyasu, Miyazaki, Masaki, Nagata, Motoko, Kitagawa, Mayumi, Akahane, Kouichi, Uoto, Kouichi

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Discovery of novel thieno[2,3-d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: Synthesis, biological evaluation, and structure von Horiuchi, Takao, Chiba, Jun, Uoto, Kouichi, Soga, Tsunehiko

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Discovery of Novel Thieno[2,3-d]pyrimidin-4-yl Hydrazone-Based Cyclin-Dependent Kinase 4 Inhibitors: Synthesis, Biological Evaluation and Structure-Activity Relationships von Takao HORIUCHIa, Yasuyuki TAKEDAa, Noriyasu HAGINOYAa, Masaki MIYAZAKIa, Motoko NAGATAb, Mayumi KITAGAWAb, Kouichi AKAHANEb, Kouichi UOTOa

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A Useful Method for Deprotection of the Protective Allyl Group at the Anomeric Oxygen of Carbohydrate Moieties Using Tetrakis(triphenylphosphine)palladium von NAKAYAMA, Kiyoshi, UOTO, Kouichi, HIGASHI, Kunio, SOGA, Tsunehiko, KUSAMA, Tsuneo

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A new method to modify the C-4 position of 10-deacetylbaccatin III von UOTO, K, TAKENOSHITA, H, ISHIYAMA, T, TERASAWA, H, SOGA, T

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New highly active taxoids from 9β-dihydrobaccatin-9,10-acetals. Part 3 von Takeda, Yasuyuki, Yoshino, Toshiharu, Uoto, Kouichi, Chiba, Jun, Ishiyama, Takashi, Iwahana, Michio, Jimbo, Takeshi, Tanaka, Noriko, Terasawa, Hirofumi, Soga, Tsunehiko

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New highly active taxoids from 9β-dihydrobaccatin-9,10-acetals von ISHIYAMA, Takashi, LIMURA, Shin, OHSUKI, Satoru, UOTO, Kouichi, TERASAWA, Hirofumi, SOGA, Tsunehiko

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New highly active taxoids from 9β-dihydrobaccatin-9,10-acetals. Part 5 von Takeda, Yasuyuki, Uoto, Kouichi, Iwahana, Michio, Jimbo, Takeshi, Nagata, Motoko, Atsumi, Ryo, Ono, Chiho, Tanaka, Noriko, Terasawa, Hirofumi, Soga, Tsunehiko

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