The Recombinant Bacille Calmette-Guérin Vaccine VPM1002: Ready for Clinical Efficacy Testing von Nieuwenhuizen, Natalie E, Kulkarni, Prasad S, Shaligram, Umesh, Cotton, Mark F, Rentsch, Cyrill A, Eisele, Bernd, Grode, Leander, Kaufmann, Stefan H E

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The Preclinical Evaluation of a Second-Generation Antivenom for Treating Snake Envenoming in India von Attarde, Saurabh, Iyer, Ashwin, Khochare, Suyog, Shaligram, Umesh, Vikharankar, Mayur, Sunagar, Kartik

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Scalable, methanol‐free manufacturing of the SARS‐CoV‐2 receptor‐binding domain in engineered Komagataella phaffii von Dalvie, Neil C., Biedermann, Andrew M., Rodriguez‐Aponte, Sergio A., Naranjo, Christopher A., Rao, Harish D., Rajurkar, Meghraj P., Lothe, Rakesh R., Shaligram, Umesh S., Johnston, Ryan S., Crowell, Laura E., Castelino, Seraphin, Tracey, Mary K., Whittaker, Charles A., Love, J. Christopher

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Passive immunization with equine RBD-specific Fab protects K18-hACE2-mice against Alpha or Beta variants of SARS-CoV-2 von Barbier, Mariette, Lee, Katherine S., Vikharankar, Mayur S., Rajpathak, Shriram N., Kadam, Nandkumar, Wong, Ting Y., Russ, Brynnan P., Cyphert, Holly A., Miller, Olivia A., Rader, Nathaniel A., Cooper, Melissa, Kang, Jason, Sen-Kilic, Emel, Wong, Zeriel Y., Winters, Michael T., Bevere, Justin R., Martinez, Ivan, Devarumath, Rachayya, Shaligram, Umesh S., Damron, F. Heath

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Multiplexed bead-based assay for the simultaneous quantification of human serum IgG antibodies to tetanus, diphtheria, pertussis toxin, filamentous hemagglutinin, and pertactin von Rathod, Vishal, Kadam, Laxmikant, Gautam, Manish, Gumma, Prabhu Dasu, Marke, Kevin, Asokanathan, Cathy, Douglas-Bardsley, Alex, Hassell, Laura, Bhandare, Sachin, Gupta, Sumit, Parekh, Sameer, Pujari, Pramod, Rao, Harish, Sharma, Hitt, Shaligram, Umesh, Gairola, Sunil

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Molecular engineering of a cryptic epitope in Spike RBD improves manufacturability and neutralizing breadth against SARS-CoV-2 variants von Rodriguez-Aponte, Sergio A., Dalvie, Neil C., Wong, Ting Y., Johnston, Ryan S., Naranjo, Christopher A., Bajoria, Sakshi, Kumru, Ozan S., Kaur, Kawaljit, Russ, Brynnan P., Lee, Katherine S., Cyphert, Holly A., Barbier, Mariette, Rao, Harish D., Rajurkar, Meghraj P., Lothe, Rakesh R., Shaligram, Umesh S., Batwal, Saurabh, Chandrasekaran, Rahul, Nagar, Gaurav, Kleanthous, Harry, Biswas, Sumi, Bevere, Justin R., Joshi, Sangeeta B., Volkin, David B., Damron, F. Heath, Love, J. Christopher

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A Phase 3, randomized, non-inferiority study of a heterologous booster dose of SARS CoV-2 recombinant spike protein vaccine in adults von Kulkarni, Prasad S., Gunale, Bhagwat, Kohli, Sunil, Lalwani, Sanjay, Tripathy, Srikanth, Kar, Sonali, Raut, Sidram, Kulkarni, Praveen, Apte, Aditi, Bavdekar, Ashish, Bhalla, Hira Lal, Plested, Joyce S., Cloney-Clark, Shane, Zhu, MingZhu, Kalkeri, Raj, Pryor, Melinda, Hamilton, Stephanie, Thakar, Madhuri, Sannidhi, Ranga S., Baranwal, Punjita, Bhamare, Chetanraj, Dharmadhikari, Abhijeet, Gupta, Manish, Poonawalla, Cyrus S., Shaligram, Umesh, Kapse, Dhananjay

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Comparative genomics of whole-cell pertussis vaccine strains from India von Alai, Shweta, Ghattargi, Vikas C., Gautam, Manish, Patel, Krunal, Pawar, Shrikant P., Dhotre, Dhiraj P., Shaligram, Umesh, Gairola, Sunil

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Safety and immunogenicity of an indigenously developed tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine (Tdap) in adults, adolescents, and children in India von Sharma, Hitt J, Parekh, Sameer, Pujari, Pramod, Shewale, Sunil, Desai, Shivani, Kawade, Anand, Ravi, Mandyam, Oswal, Jitendra, James, Saji, Mahantashetti, N., Munshi, Renuka, Ghosh, Apurba, Rao, Venkateshwar, Balsubramaniam, Sundaram, Varughese, P., Somshekhar, A., Ginsburg, Amy Sarah, Rao, Harish, Gautam, Manish, Gairola, Sunil, Shaligram, Umesh

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Validation and Suitability Assessment of Multiplex Mesoscale Discovery Immunogenicity Assay for Establishing Serological Signatures Using Vaccinated, Non-Vaccinated and Breakthroug... von Shengule, Sushant, Alai, Shweta, Bhandare, Sachin, Patil, Sumant, Gautam, Manish, Mangaonkar, Bhushan, Gupta, Sumit, Shaligram, Umesh, Gairola, Sunil

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A Phase I study to evaluate safety and tolerability of DTaP-IPV + Hib vaccine in healthy adult volunteers in India von Sharma, Hitt, Marthak, Kiran, Parekh, Sameer, Pujari, Pramod, Shewale, Sunil, Desai, Shivani, Patel, Akash, Rao, Harish, Gairola, Sunil, Shaligram, Umesh

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Results of the phase I open label clinical trial SAKK 06/14 assessing safety of intravesical instillation of VPM1002BC, a recombinant mycobacterium Bacillus Calmette Guerin (BCG),... von Rentsch, Cyrill A., Bosshard, Piet, Mayor, Gregoire, Rieken, Malte, Puschel, Heike, Wirth, Gregory, Cathomas, Richard, Parzmair, Gerald P., Grode, Leander, Eisele, Bernd, Sharma, Hitt, Gupta, Manish, Gairola, Sunil, Shaligram, Umesh, Goldenberger, Daniel, Spertini, Francois, Audran, Regine, Enoiu, Milica, Berardi, Simona, Hayoz, Stefanie, Wicki, Andreas

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SARS-CoV-2 receptor binding domain displayed on HBsAg virus-like particles elicits protective immunity in macaques von Dalvie, Neil C, Tostanoski, Lisa H, Rodriguez-Aponte, Sergio A, Kaur, Kawaljit, Bajoria, Sakshi, Kumru, Ozan S, Martinot, Amanda J, Chandrashekar, Abishek, McMahan, Katherine, Mercado, Noe B, Yu, Jingyou, Chang, Aiquan, Giffin, Victoria M, Nampanya, Felix, Patel, Shivani, Bowman, Lesley, Naranjo, Christopher A, Yun, Dongsoo, Flinchbaugh, Zach, Pessaint, Laurent, Brown, Renita, Velasco, Jason, Teow, Elyse, Cook, Anthony, Andersen, Hanne, Lewis, Mark G, Camp, Danielle L, Silverman, Judith Maxwell, Nagar, Gaurav S, Rao, Harish D, Lothe, Rakesh R, Chandrasekharan, Rahul, Rajurkar, Meghraj P, Shaligram, Umesh S, Kleanthous, Harry, Joshi, Sangeeta B, Volkin, David B, Biswas, Sumi, Love, J Christopher, Barouch, Dan H

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A Combined LC-MS and Immunoassay Approach to Characterize Preservative-Induced Destabilization of Human Papillomavirus Virus-like Particles Adsorbed to an Aluminum-Salt Adjuvant von Caringal, Ria T, Hickey, John M, Sharma, Nitya, Jerajani, Kaushal, Bewaji, Oluwadara, Brendle, Sarah, Christensen, Neil, Batwal, Saurabh, Mahedvi, Mustafa, Rao, Harish, Dogar, Vikas, Chandrasekharan, Rahul, Shaligram, Umesh, Joshi, Sangeeta B, Volkin, David B

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A phase-I, open label clinical trial to assess the safety & tolerability of qHPV vaccine manufactured by Serum Institute of India Pvt. Ltd. in adults von Sharma, Hitt, Anil, K., Parekh, Sameer, Pujari, Pramod, Shewale, Sunil, Desai, Shivani, Madhusudhan, R.L., Patel, Jaya, Eswaraiah, Anand, Rao, Harish, Gairola, Sunil, Shaligram, Umesh

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Large-Scale Purification and Characterization of Recombinant Receptor-Binding Domain (RBD) of SARS-CoV-2 Spike Protein Expressed in Yeast von Nagar, Gaurav, Jain, Siddharth, Rajurkar, Meghraj, Lothe, Rakesh, Rao, Harish, Majumdar, Sourav, Gautam, Manish, Rodriguez-Aponte, Sergio A, Crowell, Laura E, Love, J Christopher, Dandekar, Prajakta, Puranik, Amita, Gairola, Sunil, Shaligram, Umesh, Jain, Ratnesh

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Challenge studies in Rhesus monkeys immunized with candidate hepatitis E vaccines: DNA, DNA-prime-protein-boost and DNA-protein encapsulated in liposomes von Arankalle, Vidya A, Lole, Kavita S, Deshmukh, Tejaswini M, Srivastava, Shubham, Shaligram, Umesh S

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RBD-VLP Vaccines Adjuvanted with Alum or SWE Protect K18-hACE2 Mice against SARS-CoV-2 VOC Challenge von Wong, Ting Y, Russ, Brynnan P, Lee, Katherine S, Miller, Olivia A, Kang, Jason, Cooper, Melissa, Winters, Michael T, Rodriguez-Aponte, Sergio A, Dalvie, Neil C, Johnston, Ryan S, Rader, Nathaniel A, Wong, Zeriel Y, Cyphert, Holly A, Martinez, Ivan, Shaligram, Umesh, Batwal, Saurabh, Lothe, Rakesh, Chandrasekaran, Rahul, Nagar, Gaurav, Rajurkar, Meghraj, Rao, Harish, Bevere, Justin R, Barbier, Mariette, Love, J Christopher, Damron, F Heath

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Development of candidate combination vaccine for hepatitis E and hepatitis B: A liposome encapsulation approach von Shrivastava, Shubham, Lole, Kavita S, Tripathy, Anuradha S, Shaligram, Umesh S, Arankalle, Vidya A

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Development and validation of capillary electrophoresis sodium dodecyl sulfate (CE-SDS) method for purity analysis of pertussis toxin, filamentous haemagglutinin and pertactin anti... von Thorat, Shrikant, Ogale, Pratik, Gautam, Manish, Shaligram, Umesh, Gairola, Sunil

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