Build–Couple–Transform: A Paradigm for Lead-like Library Synthesis with Scaffold Diversity von Uguen, Mélanie, Davison, Gemma, Sprenger, Lukas J., Hunter, James H., Martin, Mathew P., Turberville, Shannon, Watt, Jessica E., Golding, Bernard T., Noble, Martin E. M., Stewart, Hannah L., Waring, Michael J.

Volltext

SETDB1 Triple Tudor Domain Ligand, (R,R)‑59, Promotes Methylation of Akt1 in Cells von Uguen, Mélanie, Deng, Yu, Li, Fengling, Shell, Devan J., Norris-Drouin, Jacqueline L., Stashko, Michael A., Ackloo, Suzanne, Arrowsmith, Cheryl H., James, Lindsey I., Liu, Pengda, Pearce, Kenneth H., Frye, Stephen V.

Volltext

Microwave-assisted synthesis of 4-oxo-2-butenoic acids by aldol-condensation of glyoxylic acid von Uguen, Mélanie, Gai, Conghao, Sprenger, Lukas J, Liu, Hang, Leach, Andrew G, Waring, Michael J

Volltext

Discovery of hit compounds for methyl-lysine reader proteins from a target class DNA-encoded library von Shell, Devan J., Rectenwald, Justin M., Buttery, Peter H., Johnson, Rebecca L., Foley, Caroline A., Guduru, Shiva K.R., Uguen, Mélanie, Rubiano, Juanita Sanchez, Zhang, Xindi, Li, Fengling, Norris-Drouin, Jacqueline L., Axtman, Matthew, Brian Hardy, P., Vedadi, Masoud, Frye, Stephen V., James, Lindsey I., Pearce, Kenneth H.

Volltext

Histopathological factors help to predict lymph node metastases more efficiently than extra-nodal recurrences in submucosa invading pT1 colorectal cancer von Barel, Fanny, Cariou, Mélanie, Saliou, Philippe, Kermarrec, Tiphaine, Auffret, Anaïs, Samaison, Laura, Bourhis, Amélie, Badic, Bogdan, Jézéquel, Julien, Cholet, Franck, Bail, Jean-Pierre, Marcorelles, Pascale, Nousbaum, Jean-Baptiste, Robaszkiewicz, Michel, Doucet, Laurent, Uguen, Arnaud

Volltext

Microsatellite instability diagnosis using the fully automated Idylla platform: feasibility study of an in-house rapid molecular testing ancillary to immunohistochemistry in pathol... von Samaison, Laura, Grall, Mélanie, Staroz, Frédéric, Uguen, Arnaud

Volltext

Discoidin Domain Receptor 2 orchestrates melanoma resistance combining phenotype switching and proliferation von Sala, Margaux, Allain, Nathalie, Moreau, Mélanie, Jabouille, Arnaud, Henriet, Elodie, Abou-Hammoud, Aya, Uguen, Arnaud, Di-Tommaso, Sylvaine, Dourthe, Cyril, Raymond, Anne-Aurélie, Dupuy, Jean-William, Gerard, Emilie, Dugot-Senant, Nathalie, Rousseau, Benoit, Merlio, Jean-Phillipe, Pham-Ledart, Anne, Vergier, Béatrice, Tartare-Deckert, Sophie, Moreau, Violaine, Saltel, Frédéric

Volltext

A gene expression and pre-mRNA splicing signature that marks the adenoma-adenocarcinoma progression in colorectal cancer von Pesson, Marine, Volant, Alain, Uguen, Arnaud, Trillet, Kilian, De La Grange, Pierre, Aubry, Marc, Daoulas, Mélanie, Robaszkiewicz, Michel, Le Gac, Gérald, Morel, Alain, Simon, Brigitte, Corcos, Laurent

Volltext

MSI-High RAS-BRAF wild-type colorectal adenocarcinomas with MLH1 loss have a high frequency of targetable oncogenic gene fusions whose diagnoses are feasible using methods easy-to-... von Bocciarelli, Claire, Caumont, Charline, Samaison, Laura, Cariou, Mélanie, Aline-Fardin, Aude, Doucet, Laurent, Roudié, Jean, Terris, Benoît, Merlio, Jean-Philippe, Marcorelles, Pascale, Cappellen, David, Uguen, Arnaud

Volltext

Evaluation of KRAS, NRAS and BRAF mutational status and microsatellite instability in early colorectal carcinomas invading the submucosa (pT1): towards an in-house molecular progno... von Bourhis, Amélie, De Luca, Caterina, Cariou, Mélanie, Vigliar, Elena, Barel, Fanny, Conticelli, Floriana, Marcorelles, Pascale, Nousbaum, Jean-Baptiste, Robaszkiewicz, Michel, Samaison, Laura, Badic, Bogdan, Doucet, Laurent, Troncone, Giancarlo, Uguen, Arnaud

Volltext

High reproducibility is attainable in assessing histoprognostic parameters of pT1 colorectal cancer using routine histopathology slides and immunohistochemistry analyses von Barel, Fanny, Auffret, Anaïs, Cariou, Mélanie, Kermarrec, Tiphaine, Samaison, Laura, Bourhis, Amélie, Badic, Bogdan, Jézéquel, Julien, Cholet, Franck, Bail, Jean-Pierre, Marcorelles, Pascale, Nousbaum, Jean-Baptiste, Robaszkiewicz, Michel, Doucet, Laurent, Uguen, Arnaud

Volltext

Stepwise use of genomics and transcriptomics technologies increases diagnostic yield in Mendelian disorders von Colin, Estelle, Duffourd, Yannis, Chevarin, Martin, Tisserant, Emilie, Verdez, Simon, Paccaud, Julien, Bruel, Ange-Line, Tran Mau-Them, Frédéric, Denommé-Pichon, Anne-Sophie, Thevenon, Julien, Safraou, Hana, Besnard, Thomas, Goldenberg, Alice, Cogné, Benjamin, Isidor, Bertrand, Delanne, Julian, Sorlin, Arthur, Moutton, Sébastien, Fradin, Mélanie, Dubourg, Christèle, Gorce, Magali, Bonneau, Dominique, El Chehadeh, Salima, Debray, François-Guillaume, Doco-Fenzy, Martine, Uguen, Kevin, Chatron, Nicolas, Aral, Bernard, Marle, Nathalie, Kuentz, Paul, Boland, Anne, Olaso, Robert, Deleuze, Jean-François, Sanlaville, Damien, Callier, Patrick, Philippe, Christophe, Thauvin-Robinet, Christel, Faivre, Laurence, Vitobello, Antonio

Volltext

A Gene Expression and Pre-mRNA Splicing Signature That Marks the Adenoma-Adenocarcinoma Progression in Colorectal Cancer: e87761 von Pesson, Marine, Volant, Alain, Uguen, Arnaud, Trillet, Kilian, Grange, Pierre DeLa, Aubry, Marc, Daoulas, Melanie, Robaszkiewicz, Michel, Gac, Gerald Le, Morel, Alain

Volltext