P4586Bilateral internal thoracic artery grafting neutralizes detrimental effect of diabetes on survival in patients with ischemic cardiomyopathy von Kainuma, S, Taniguchi, K T, Toda, K T, Miyagawa, S M, Yoshikawa, Y Y, Hata, H H, Yoshioka, D Y, Ueno, T U, Kuratani, T K, Sakaguchi, T S, Funatsu, T F, Kondoh, H K, Masai, T M, Daimon, T D, Sawa, Y S

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High tumor mutation burden fails to predict immune checkpoint blockade response across all cancer types von McGrail, D.J., Pilié, P.G., Rashid, N.U., Voorwerk, L., Slagter, M., Kok, M., Jonasch, E., Khasraw, M., Heimberger, A.B., Lim, B., Ueno, N.T., Litton, J.K., Ferrarotto, R., Chang, J.T., Moulder, S.L., Lin, S.-Y.

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Rates of immune cell infiltration in patients with triple-negative breast cancer by molecular subtype von Harano, Kenichi, Wang, Ying, Lim, Bora, Seitz, Robert S, Morris, Stephan W, Bailey, Daniel B, Hout, David R, Skelton, Rachel L, Ring, Brian Z, Masuda, Hiroko, Rao, Arvind U K, Laere, Steven Van, Bertucci, Francois, Woodward, Wendy A, Reuben, James M, Krishnamurthy, Savitri, Ueno, Naoto T

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Validation of cancer-type-dependent benefit from immune checkpoint blockade in TMB-H tumors identified by the FoundationOne CDx assay von McGrail, D.J., Pilié, P.G., Rashid, N.U., Voorwerk, L., Slagter, M., Kok, M., Jonasch, E., Khasraw, M., Heimberger, A.B., Ueno, N.T., Ferrarotto, R., Chang, J.T., Lin, S.-Y.

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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes von Klionsky, Daniel J., Abeliovich, Hagai, Agostinis, Patrizia, Aliev, Gjumrakch, Ballabio, Andrea, Bamber, Bruce A., Bi, Xiaoning, Biard-Piechaczyk, Martine, Bredesen, Dale E., Cebollero, Eduardo, Cecconi, Francesco, Chu, Charleen T., Chung, Jongkyeong, Clarke, Peter G.H., Clarke, Steven G., Cleveland, John L., Colombo, María Isabel, Coto-Montes, Ana, Deretic, Vojo, Di Sano, Federica, Dinesh-Kumar, Savithramma P., Eissa, N. Tony, DiFiglia, Marian, Dorsey, Frank C., Dröge, Wulf, Dron, Michel, Duszenko, Michael, Esclatine, Audrey, Fésüs, László, Finley, Kim D., Fujisaki, Kozo, Gewirtz, David A., Gohla, Antje, Goldberg, Alfred L., Gonzalez, Ramon, He, You-Wen, Hill, Joseph A., Huang, Wei-Pang, Jäättelä, Marja, Jiang, Xuejun, Jin, Shengkan V., Kang, Chanhee, Kelekar, Ameeta, Kiel, Jan A.K.W., Kimchi, Adi, Kinsella, Timothy J., Kiselyov, Kirill, Kitamoto, Katsuhiko, Komatsu, Masaaki, Kondo, Seiji, Kumar, Rakesh, Laporte, Marianne, Liou, Willisa, Macleod, Kay F., Martinet, Wim, Mautner, Josef, Meléndez, Alicia, Miotto, Giovanni, Mistiaen, Wilhelm P., Münz, Christian, Naqvi, Naweed I., Nishino, Ichizo, Noda, Takeshi, Ogawa, Michinaga, Ozpolat, Bulent, Paglin, Shoshana, Palmer, Glen E., Perlmutter, David H., Piacentini, Mauro, Pinkas-Kramarski, Ronit, Rami, Abdelhaq, Sandri, Marco, Sass, Miklós, Seleverstov, Oleksandr, Settleman, Jeffrey, Shacka, John J., Sibirny, Andrei A., Silva-Zacarin, Elaine C.M., Simonsen, Anne, Smith, Mark A., Srinivas, Vickram, Stenmark, Harald, Sulzer, David, Tabas, Ira, Takeshita, Fumihiko, Tanaka, Keiji, Taylor, J. Paul, Terman, Alexei, Thompson, Craig B., Tolkovsky, Aviva M., Tumanovska, Lesya V., Uchiyama, Yasuo, Ueno, Takashi, Uzcátegui, Néstor L., Vaquero, Eva C., Webster, Paul, Xi, Zhijun, Yue, Zhenyu, Zheng, Xiaoxiang, Deter, Russell L.

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Underuse of Trimodality Treatment Affects Survival for Patients With Inflammatory Breast Cancer: An Analysis of Treatment and Survival Trends From the National Cancer Database von RUETH, Natasha M, LIN, Heather Y, BEDROSIAN, Isabelle, SHAITELMAN, Simona F, UENO, Naoto T, YU SHEN, BABIERA, Gildy

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Use of the fiberglass reinforcement method in thermoplastic mouthguard materials to improve flexural properties for enhancement of functionality von CHUREI, Hiroshi, CHOWDHURY, Ruman Uddin, YOSHIDA, Yuriko, TANABE, Gen, FUKASAWA, Shintaro, SHIRAKO, Takahiro, WADA, Takahiro, UO, Motohiro, TAKAHASHI, Hidekazu, UENO, Toshiaki

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A Genomic Predictor of Response and Survival Following Taxane-Anthracycline Chemotherapy for Invasive Breast Cancer von Hatzis, Christos, Pusztai, Lajos, Valero, Vicente, Booser, Daniel J, Esserman, Laura, Lluch, Ana, Vidaurre, Tatiana, Holmes, Frankie, Souchon, Eduardo, Wang, Hongkun, Martin, Miguel, Cotrina, José, Gomez, Henry, Hubbard, Rebekah, Chacón, J. Ignacio, Ferrer-Lozano, Jaime, Dyer, Richard, Buxton, Meredith, Gong, Yun, Wu, Yun, Ibrahim, Nuhad, Andreopoulou, Eleni, Ueno, Naoto T, Hunt, Kelly, Yang, Wei, Nazario, Arlene, DeMichele, Angela, O’Shaughnessy, Joyce, Hortobagyi, Gabriel N, Symmans, W. Fraser

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Reply to: ‘Real-world prevalence across 159 872 patients with cancer supports the clinical utility of TMB-H to define metastatic solid tumors for treatment with pembrolizumab.’ by... von McGrail, D.J., Pilié, P.G., Rashid, N.U., Voorwerk, L., Slagter, M., Kok, M., Jonasch, E., Khasraw, M., Heimberger, A.B., Ueno, N.T., Ferrarotto, R., Chang, J.T., Lin, S.-Y.

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Circulating tumor cells and bone metastases as detected by FDG–PET/CT in patients with metastatic breast cancer von De Giorgi, U., Valero, V., Rohren, E., Mego, M., Doyle, G. V., Miller, M. C., Ueno, N. T., Handy, B. C., Reuben, J. M., Macapinlac, H. A., Hortobagyi, G. N., Cristofanilli, M.

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D14–SCFD3-dependent degradation of D53 regulates strigolactone signalling von Zhou, Feng, Lin, Qibing, Zhu, Lihong, Ren, Yulong, Zhou, Kunneng, Shabek, Nitzan, Wu, Fuqing, Mao, Haibin, Dong, Wei, Gan, Lu, Ma, Weiwei, Gao, He, Chen, Jun, Yang, Chao, Wang, Dan, Tan, Junjie, Zhang, Xin, Guo, Xiuping, Wang, Jiulin, Jiang, Ling, Liu, Xi, Chen, Weiqi, Chu, Jinfang, Yan, Cunyu, Ueno, Kotomi, Ito, Shinsaku, Asami, Tadao, Cheng, Zhijun, Wang, Jie, Lei, Cailin, Zhai, Huqu, Wu, Chuanyin, Wang, Haiyang, Zheng, Ning, Wan, Jianmin

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Circulating Tumor Cells (CTC) Are Associated with Defects in Adaptive Immunity in Patients with Inflammatory Breast Cancer von Mego, M, Gao, H, Cohen, E N, Anfossi, S, Giordano, A, Sanda, T, Fouad, T M, De Giorgi, U, Giuliano, M, Woodward, W A, Alvarez, R H, Valero, V, Ueno, N T, Hortobagyi, G N, Cristofanilli, M, Reuben, J M

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Relation of Disaster Exposure With Maternal Characteristics and Obstetric Outcomes: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study von Ishikuro, Mami, Obara, Taku, Murakami, Keiko, Ueno, Fumihiko, Noda, Aoi, Kikuya, Masahiro, Sugawara, Junichi, Metoki, Hirohito, Kuriyama, Shinichi

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Inflammatory breast cancer (IBC) and patterns of recurrence : Understanding the biology of a unique disease von CRISTOFANILLI, Massimo, VALERO, Vicente, SINGLETARY, Sonja E, HORTOBAGYL, Gabriel N, BUZDAR, Aman U, KAU, Shu-Wan, BROGLIO, Kristine R, GONZALEZ-ANGULO, Ana Maria, SNEIGE, Nour, ISLAM, Rabiul, UENO, Naoto T, BUCHHOLZ, Thomas A

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Annual parallax and galactic orbit of Y Librae (IRAS 15090−0549) Mira variable star—GALORB release von Chibueze, James O, Omodaka, Toshihiro, Urago, Riku, Nagayama, Takumi, Alhassan, Jibrin A, Nishida, Yoshiro, Aralu, Ogochukwu U, van Rooyen, Ruby, Nakagawa, Akiharu, Honma, Mareki, Ueno, Yuji

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Myositis with sarcoplasmic inclusions in Nakajo–Nishimura syndrome: a genetic inflammatory myopathy von Ayaki, T., Murata, K., Kanazawa, N., Uruha, A., Ohmura, K., Sugie, K., Kasagi, S., Li, F., Mori, M., Nakajima, R., Sasai, T., Nishino, I., Ueno, S., Urushitani, M., Furukawa, F., Ito, H., Takahashi, R.

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A sperm-activating peptide controls a cGMP-signaling pathway in starfish sperm von Matsumoto, Midori, Solzin, Johannes, Helbig, Annika, Hagen, Volker, Ueno, Sei-ichi, Kawase, Osamu, Maruyama, Yoshinori, Ogiso, Manabu, Godde, Matthias, Minakata, Hiroyuki, Kaupp, U.Benjamin, Hoshi, Motonori, Weyand, Ingo

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Establishment of experimental models to evaluate the effectiveness of dental trauma splints von SHIRAKO, Takahiro, CHUREI, Hiroshi, WADA, Takahiro, UO, Motohiro, UENO, Toshiaki

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Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts von Murry, Charles E, Laflamme, Michael A, Chen, Kent Y, Naumova, Anna V, Muskheli, Veronica, Fugate, James A, Dupras, Sarah K, Reinecke, Hans, Xu, Chunhui, Hassanipour, Mohammad, Police, Shailaja, O'Sullivan, Chris, Collins, Lila, Chen, Yinhong, Minami, Elina, Gill, Edward A, Ueno, Shuichi, Yuan, Chun, Gold, Joseph

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133MO Pembrolizumab (pembro) plus gemcitabine and cisplatin (gem/cis) compared with gem/cis alone for patients (pts) with advanced biliary tract cancer (BTC): Updated efficacy and... von Finn, R.S., Ueno, M., Yoo, C., Ren, Z., Furuse, J., Kelley, R.K., Chan, S.L., Edeline, J., Klumpen, H.J., Yau, T., Oh, S.C., Ozaka, M., Kim, J.G., Park, J.O., Vogel, A., Valle, J.W., Yu, L., Malhotra, U., Siegel, A.B., Qin, S.

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