STAT5A/B Blockade Sensitizes Prostate Cancer to Radiation through Inhibition of RAD51 and DNA Repair von Maranto, Cristina, Udhane, Vindhya, Hoang, David T, Gu, Lei, Alexeev, Vitali, Malas, Kareem, Cardenas, Karmel, Brody, Jonathan R, Rodeck, Ulrich, Bergom, Carmen, Iczkowski, Ken A, Jacobsohn, Ken, See, William, Schmitt, Sara M, Nevalainen, Marja T

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Second-Generation Jak2 Inhibitors for Advanced Prostate Cancer: Are We Ready for Clinical Development? von Beinhoff, Paul, Sabharwal, Lavannya, Udhane, Vindhya, Maranto, Cristina, LaViolette, Peter S., Jacobsohn, Kenneth M., Tsai, Susan, Iczkowski, Kenneth A., Wang, Liang, Hall, William A., Dehm, Scott M., Kilari, Deepak, Nevalainen, Marja T.

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Cytokines, JAK-STAT Signaling and Radiation-Induced DNA Repair in Solid Tumors: Novel Opportunities for Radiation Therapy von Hall, William A., Sabharwal, Lavannya, Udhane, Vindhya, Maranto, Cristina, Nevalainen, Marja T.

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Enzalutamide-Induced Feed-Forward Signaling Loop Promotes Therapy-Resistant Prostate Cancer Growth Providing an Exploitable Molecular Target for Jak2 Inhibitors von Udhane, Vindhya, Maranto, Cristina, Hoang, David T., Gu, Lei, Erickson, Andrew, Devi, Savita, Talati, Pooja G., Banerjee, Anjishnu, Iczkowski, Kenneth A., Jacobsohn, Kenneth, See, William A., Mirtti, Tuomas, Kilari, Deepak, Nevalainen, Marja T.

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The role of enzalutamide-induced hyperactive Jak2-Stat5 feed-forward signaling loop on enzalutamide-resistant prostate cancer growth and as a therapeutic target for second-line tre... von Udhane, Vindhya, Maranto, Cristina, Hoang, David, Erickson, Andrew, Devi, Savita, Jacobsohn, Kenneth, Iczkowski, Kenneth, See, William, Kilari, Deepak, Mirtti, Tuomas, Nevalainen, Marja

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Positive STAT5 Protein and Locus Amplification Status Predicts Recurrence after Radical Prostatectomy to Assist Clinical Precision Management of Prostate Cancer von Haddad, Bassem R, Erickson, Andrew, Udhane, Vindhya, LaViolette, Peter S, Rone, Janice D, Kallajoki, Markku A, See, William A, Rannikko, Antti, Mirtti, Tuomas, Nevalainen, Marja T

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Abstract B073: Stat5a/b blockade sensitizes prostate cancer to radiation through inhibition of Rad51 and DNA repair von Maranto, Cristina, Udhane, Vindhya, Dagvadorj, Ayush, Hoang, David T., Gu, Lei, Alexeev, Vitali, Malas, Kareem, Cardenas, Karmel, Koptyra, Mateusz, Brody, Jonathan R., Rodeck, Ulrich, Bergom, Carmen, Iczkowski, Ken A., Jacobsohn, Ken, See, William, Schmitt, Sara M., Nevalainen, Marja T.

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NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers von Sun, Yunguang, Yang, Ning, Utama, Fransiscus E., Udhane, Sameer S., Zhang, Junling, Peck, Amy R., Yanac, Alicia, Duffey, Katherine, Langenheim, John F., Udhane, Vindhya, Xia, Guanjun, Peterson, Jess F., Jorns, Julie M., Nevalainen, Marja T., Rouet, Romain, Schofield, Peter, Christ, Daniel, Ormandy, Christopher J., Rosenberg, Anne L., Chervoneva, Inna, Tsaih, Shirng-Wern, Flister, Michael J., Fuchs, Serge Y., Wagner, Kay-Uwe, Rui, Hallgeir

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Stat5 induces androgen receptor ( AR ) gene transcription in prostate cancer and offers a druggable pathway to target AR signaling von Maranto, Cristina, Sabharwal, Lavannya, Udhane, Vindhya, Pitzen, Samuel P, McCluskey, Braedan, Qi, Songyan, O'Connor, Christine, Devi, Savita, Johnson, Scott, Jacobsohn, Kenneth, Banerjee, Anjishnu, Iczkowski, Kenneth A, Wang, Liang, Dehm, Scott M, Nevalainen, Marja T

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Prospects for Clinical Development of Stat5 Inhibitor IST5-002: High Transcriptomic Specificity in Prostate Cancer and Low Toxicity In Vivo von Maranto, Cristina, Udhane, Vindhya, Jia, Jing, Verma, Ranjit, Mueller-Newen, Gerhard, LaViolette, Peter S., Pereckas, Michael, Sabharwal, Lavannya, Terhune, Scott, Pattabiraman, Nagarajan, Njar, Vincent C. O., Imig, John D., Wang, Liang, Nevalainen, Marja T.

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