Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography von Ubah, Obinna C., Lake, Eric W., Gunaratne, Gihan S., Gallant, Joseph P., Fernie, Marie, Robertson, Austin J., Marchant, Jonathan S., Bold, Tyler D., Langlois, Ryan A., Matchett, William E., Thiede, Joshua M., Shi, Ke, Yin, Lulu, Moeller, Nicholas H., Banerjee, Surajit, Ferguson, Laura, Kovaleva, Marina, Porter, Andrew J., Aihara, Hideki, LeBeau, Aaron M., Barelle, Caroline J.

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In Vitro ELISA and Cell-Based Assays Confirm the Low Immunogenicity of VNAR Therapeutic Constructs in a Mouse Model of Human RA: An Encouraging Milestone to Further Clinical Drug D... von Ubah, Obinna C., Barelle, Caroline J., Porter, Andrew J.

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An Anti-hTNF-α Variable New Antigen Receptor Format Demonstrates Superior in vivo Preclinical Efficacy to Humira® in a Transgenic Mouse Autoimmune Polyarthritis Disease Model von Ubah, Obinna C, Steven, John, Porter, Andrew J, Barelle, Caroline J

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Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic Development von Ubah, Obinna C, Steven, John, Kovaleva, Marina, Ferguson, Laura, Barelle, Charlotte, Porter, Andrew J R, Barelle, Caroline J

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In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development von Steven, John, Müller, Mischa R, Carvalho, Miguel F, Ubah, Obinna C, Kovaleva, Marina, Donohoe, Gerard, Baddeley, Thomas, Cornock, Dawn, Saunders, Kenneth, Porter, Andrew J, Barelle, Caroline Jane

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Overview, Generation, and Significance of Variable New Antigen Receptors (VNARs) as a Platform for Drug and Diagnostic Development von Pandey, Samata S., Kovaleva, Marina, Barelle, Caroline J., Ubah, Obinna C.

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In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties von Steven, John, Ubah, Obinna C., Buschhaus, Magdalena, Kovaleva, Marina, Ferguson, Laura, Porter, Andrew J., Barelle, Caroline J.

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Uveitis Therapy With Shark Variable Novel Antigen Receptor Domains Targeting Tumor Necrosis Factor Alpha or Inducible T-Cell Costimulatory Ligand von Pepple, Kathryn L, Wilson, Leslie, Van Gelder, Russell N, Kovaleva, Marina, Ubah, Obinna C, Steven, John, Barelle, Caroline J, Porter, Andrew

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Single-Domain Antibodies: Methods and Protocols von Hussack, Greg, Henry, Kevin A

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Derivative of aminoresin as potent anti-virulence agent: Synthesis, spectral (FT-IR, UV, NMR) analysis, molecular docking, effect of polar solvation dynamics, and quantum chemical... von Ubah, Chioma B., Mujafarkani, N., Sundaravadivelu, Ambika, Narendran, Nellainayagam, Godfrey, Obinna C., Ogbodo, Sopuruchukwu E., Odey, Michael O., Benjamin, Innocent, Ahamed, A. Jafar, Owen, Aniekan E., Agbo, Bassey E., Louis, Hitler

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Overcoming Challenges in Providing Radiation Therapy to Patients With Cancer in Nigeria and Experience in the National Hospital Abuja, Nigeria von Aruah, Simeon Chinedu, Asogwa, Obinna Chizoba, Ubah, Fatima I., Maurice, Nandul Nimark, Oyesegun, Rasaaq, Ige, Taofeeq A., Coleman, C. Norman, Dosanjh, Manjit, Pistenmaa, David

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Elucidating the structural basis for the enhanced antifungal activity of amide derivative against Candida albicans: a comprehensive computational investigation von Kechi, Eban L., Ubah, Chioma B., Runde, Musa, Owen, Aniekan E., Godfrey, Obinna C., Agurokpon, Daniel C., Odey, Michael O., Edet, Uwem O., Ekpong, Bassey O., Iyam, Solomon O., Benjamin, Innocent, Sampathkumar, Gopinath

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