A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents von Maschmeyer, Ilka, Lorenz, Alexandra K, Schimek, Katharina, Hasenberg, Tobias, Ramme, Anja P, Hübner, Juliane, Lindner, Marcus, Drewell, Christopher, Bauer, Sophie, Thomas, Alexander, Sambo, Naomia Sisoli, Sonntag, Frank, Lauster, Roland, Marx, Uwe

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Functional coupling of human pancreatic islets and liver spheroids on-a-chip: Towards a novel human ex vivo type 2 diabetes model von Bauer, Sophie, Wennberg Huldt, Charlotte, Kanebratt, Kajsa P., Durieux, Isabell, Gunne, Daniela, Andersson, Shalini, Ewart, Lorna, Haynes, William G., Maschmeyer, Ilka, Winter, Annika, Ämmälä, Carina, Marx, Uwe, Andersson, Tommy B.

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Chip-based human liver–intestine and liver–skin co-cultures – A first step toward systemic repeated dose substance testing in vitro von Maschmeyer, Ilka, Hasenberg, Tobias, Jaenicke, Annika, Lindner, Marcus, Lorenz, Alexandra Katharina, Zech, Julie, Garbe, Leif-Alexander, Sonntag, Frank, Hayden, Patrick, Ayehunie, Seyoum, Lauster, Roland, Marx, Uwe, Materne, Eva-Maria

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A dynamic multi-organ-chip for long-term cultivation and substance testing proven by 3D human liver and skin tissue co-culture von Wagner, Ilka, Materne, Eva-Maria, Brincker, Sven, Süßbier, Ute, Frädrich, Caroline, Busek, Mathias, Sonntag, Frank, Sakharov, Dmitry A, Trushkin, Evgeny V, Tonevitsky, Alexander G, Lauster, Roland, Marx, Uwe

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Human multi-organ chip co-culture of bronchial lung culture and liver spheroids for substance exposure studies von Schimek, Katharina, Frentzel, Stefan, Luettich, Karsta, Bovard, David, Rütschle, Isabel, Boden, Laura, Rambo, Felix, Erfurth, Hendrik, Dehne, Eva-Maria, Winter, Annika, Marx, Uwe, Hoeng, Julia

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Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing von Marx, Uwe

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A multi-organ chip co-culture of neurospheres and liver equivalents for long-term substance testing von Materne, Eva-Maria, Ramme, Anja Patricia, Terrasso, Ana Paula, Serra, Margarida, Alves, Paula Marques, Brito, Catarina, Sakharov, Dmitry A., Tonevitsky, Alexander G., Lauster, Roland, Marx, Uwe

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Integrated experimental-computational analysis of a HepaRG liver-islet microphysiological system for human-centric diabetes research von Casas, Belén, Vilén, Liisa, Bauer, Sophie, Kanebratt, Kajsa P, Wennberg Huldt, Charlotte, Magnusson, Lisa, Marx, Uwe, Andersson, Tommy B, Gennemark, Peter, Cedersund, Gunnar

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'Human-on-a-chip' Developments: A Translational Cutting- edge Alternative to Systemic Safety Assessment and Efficiency Evaluation of Substances in Laboratory Animals and Man? von MARX, Uwe, WALLES, Heike, HOFFMANN, Silke, LINDNER, Gerd, HORLAND, Reyk, SONNTAG, Frank, KLOTZBACH, Udo, SAKHAROV, Dmitry, TONEVITSKY, Alexander, LAUSTER, Roland

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Demonstration of the first‐pass metabolism in the skin of the hair dye, 4‐amino‐2‐hydroxytoluene, using the Chip2 skin–liver microphysiological model von Tao, Thi Phuong, Brandmair, Katrin, Gerlach, Silke, Przibilla, Julia, Géniès, Camille, Jacques‐Jamin, Carine, Schepky, Andreas, Marx, Uwe, Hewitt, Nicola J., Maschmeyer, Ilka, Kühnl, Jochen

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Metal‐Specific Biomaterial Accumulation in Human Peri‐Implant Bone and Bone Marrow von Schoon, Janosch, Hesse, Bernhard, Rakow, Anastasia, Ort, Melanie J., Lagrange, Adrien, Jacobi, Dorit, Winter, Annika, Huesker, Katrin, Reinke, Simon, Cotte, Marine, Tucoulou, Remi, Marx, Uwe, Perka, Carsten, Duda, Georg N., Geissler, Sven

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Reconstructed human skin shows epidermal invagination towards integrated neopapillae indicating early hair follicle formation in vitro von Vahav, Irit, Broek, Lenie J., Thon, Maria, Monsuur, Hanneke N., Spiekstra, Sander W., Atac, Beren, Scheper, Rik J., Lauster, Roland, Lindner, Gerd, Marx, Uwe, Gibbs, Susan

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Autologous induced pluripotent stem cell-derived four-organ-chip von Ramme, Anja Patricia, Koenig, Leopold, Hasenberg, Tobias, Schwenk, Christine, Magauer, Corinna, Faust, Daniel, Lorenz, Alexandra K, Krebs, Anna-Catharina, Drewell, Christopher, Schirrmann, Kerstin, Vladetic, Alexandra, Lin, Grace-Chiaen, Pabinger, Stephan, Neuhaus, Winfried, Bois, Frederic, Lauster, Roland, Marx, Uwe, Dehne, Eva-Maria

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Generation of two additional integration-free iPSC lines from related human donors von Ramme, Anja Patricia, Faust, Daniel, Koenig, Leopold, Nguyen, Nhutuyen, Marx, Uwe

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Development of a microphysiological skin-liver-thyroid Chip3 model and its application to evaluate the effects on thyroid hormones of topically applied cosmetic ingredients under c... von Tao, Thi-Phuong, Maschmeyer, Ilka, LeCluyse, Edward L, Rogers, Eda, Brandmair, Katrin, Gerlach, Silke, Przibilla, Julia, Kern, Fredy, Genies, Camille, Jacques, Carine, Najjar, Abdulkarim, Schepky, Andreas, Marx, Uwe, Kühnl, Jochen, Hewitt, Nicola J

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A Human Stem Cell-Derived Brain-Liver Chip for Assessing Blood-Brain-Barrier Permeation of Pharmaceutical Drugs von Koenig, Leopold, Ramme, Anja Patricia, Faust, Daniel, Mayer, Manuela, Flötke, Tobias, Gerhartl, Anna, Brachner, Andreas, Neuhaus, Winfried, Appelt-Menzel, Antje, Metzger, Marco, Marx, Uwe, Dehne, Eva-Maria

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Skin Irritation Testing beyond Tissue Viability: Fucoxanthin Effects on Inflammation, Homeostasis, and Metabolism von Spagolla Napoleão Tavares, Renata, Maria-Engler, Silvya Stuchi, Colepicolo, Pio, Debonsi, Hosana Maria, Schäfer-Korting, Monika, Marx, Uwe, Gaspar, Lorena Rigo, Zoschke, Christian

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Generation of four integration-free iPSC lines from related human donors von Ramme, Anja Patricia, Faust, Daniel, Koenig, Leopold, Marx, Uwe

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Engineering Blood and Lymphatic Microvascular Networks in Fibrin Matrices von Knezevic, Lea, Schaupper, Mira, Mühleder, Severin, Schimek, Katharina, Hasenberg, Tobias, Marx, Uwe, Priglinger, Eleni, Redl, Heinz, Holnthoner, Wolfgang

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Proof-of-Concept Organ-on-Chip Study: Topical Cinnamaldehyde Exposure of Reconstructed Human Skin with Integrated Neopapillae Cultured under Dynamic Flow von Vahav, Irit, Thon, Maria, van den Broek, Lenie J, Spiekstra, Sander W, Atac, Beren, Lindner, Gerd, Schimek, Katharina, Marx, Uwe, Gibbs, Susan

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