Synthesis, deprotection, analysis and purification of RNA and ribosomes von Wincott, Francine, DiRenzo, Anthony, Shaffer, Chris, Grimm, Susan, Tracz, Danuta, Workman, Christopher, Sweedler, David, Gonzalez, Carolyn, Scaringe, Stephen, Usman, Nassim

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A phase I clinical trial of a ribozyme-based angiogenesis inhibitor targeting vascular endothelial growth factor receptor-1 for patients with refractory solid tumors von Weng, David E, Masci, Paul A, Radka, Susan F, Jackson, T Elise, Weiss, Patricia A, Ganapathi, Ram, Elson, Paul J, Capra, William B, Parker, Vann P, Lockridge, Jennifer A, Cowens, J Wayne, Usman, Nassim, Borden, Ernest C

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The Structural Basis of Hammerhead Ribozyme Self-Cleavage von Murray, James B, Terwey, Daniel P, Maloney, Lara, Karpeisky, Alexander, Usman, Nassim, Beigelman, Leonid, Scott, William G

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Conformational influence of the ribose 2'-hydroxyl group: Crystal structures of DNA-RNA chimeric duplexes von Egli, Martin, Usman, Nassim, Rich, Alexander

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Specificity for Aminoacylation of an RNA Helix: An Unpaired, Exocyclic Amino Group in the Minor Groove von Musier-Forsyth, Karin, Usman, Nassim, Scaringe, Stephen, Doudna, Jennifer, Green, Rachel, Schimmel, Paul

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The molecular structure of the complex of Hoechst 33258 and the DNA dodecamer d(CGCGAATTCGCG) von MAI-KUN TENG, NASSIM USMAN, FREDERICK, C. A, WANG, A. H.-J

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Evidence for the Rate-Limiting Departure of the 5‘-Oxygen in Nonenzymatic and Hammerhead Ribozyme-Catalyzed Reactions von Zhou, De-Min, Usman, Nassim, Wincott, Francine E, Matulic-Adamic, Jasenka, Orita, Masaya, Zhang, Li-He, Komiyama, Makoto, Kumar, Penmetcha K. R, Taira, Kazunari

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Effect of Structural Modifications on the Activity of the Leadzyme von Chartrand, Pascal, Usman, Nassim, Cedergren, Robert

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X-ray crystallographic observation of “in-line” and “adjacent” conformations in a bulged self-cleaving RNA/DNA hybrid von TERESHKO, VALENTINA, WALLACE, SCOT T., USMAN, NASSIM, WINCOTT, FRANCINE E., EGLI, MARTIN

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Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics von Usman, N, Blatt, L M

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Relationship between 2'-hydroxyls and magnesium binding in the hammerhead RNA domain: a model for ribozyme catalysis von Perreault, Jean Pierre, Labuda, Damian, Usman, Nassim, Yang, Jing Hua, Cedergren, Robert

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Characterization of HIV-1 REV protein : binding stoichiometry and minimal RNA substrate von COOK, K. S, FISK, G. J, HAUBER, J, USMAN, N, DALY, T. J, RUSCHE, J. R

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RNA Hydration:  A Detailed Look von Egli, Martin, Portmann, Stefan, Usman, Nassim

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Synthesis of 1-deoxy-d-ribofuranose phosphoramidite & the incorporation of abasic nucleotides in stem-loop II of a hammerhead ribozyme von Beigelman, Leonid, Karpeisky, Alexander, Usman, Nassim

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Angiozyme: a novel angiogenesis inhibitor von Weng, D E, Usman, N

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Synthesis and biological activities of a phosphorodithioate analog of 2′, 5′-oligoadenylate von Beigelman, Leo, Matulic-Adamic, Jasenka, Haeberli, Peter, Usman, Nassim, Dong, Beihua, Silverman, Robert H., Khamnei, Shahrzad, Torrence, Paul F.

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New Structural Motifs for Hammerhead Ribozymes. Catalytic Activity of Abasic Nucleotide Substituted Ribozymes von Beigelman, Leonid, Karpeisky, Alexander, Matulic-Adamic, Jasenka, Gonzalez, Carolyn, Usman, Nassim

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Chemical synthesis of biologically active oligoribonucleotides using beta-cyanoethyl protected ribonucleoside phosphoramidites von Scaringe, S A, Francklyn, C, Usman, N

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Safety and pharmacokinetic study of RPI.4610 (ANGIOZYME), an anti-VEGFR-1 ribozyme, in combination with carboplatin and paclitaxel in patients with advanced solid tumors von KOBAYASHI, Hiroyuki, GAIL ECKHARDT, S, WOLIN, Maurice, BASCHE, Michele L, LOCKRIDGE, Jennifer A, ROTHENBERG, Mace L, SANDIER, Alan B, O'BRYANT, Cindy L, COOPER, Wendy, HOLDEN, Scott N, AITCHISON, Roger D, USMAN, Nassim

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Rescue of Abasic Hammerhead Ribozymes by Exogenous Addition of Specific Bases von Peracchi, Alessio, Beigelman, Leonid, Usman, Nassim, Herschlag, Daniel

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