Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms von Gao, Linfeng, Emperle, Max, Guo, Yiran, Grimm, Sara A., Ren, Wendan, Adam, Sabrina, Uryu, Hidetaka, Zhang, Zhi-Min, Chen, Dongliang, Yin, Jiekai, Dukatz, Michael, Anteneh, Hiwot, Jurkowska, Renata Z., Lu, Jiuwei, Wang, Yinsheng, Bashtrykov, Pavel, Wade, Paul A., Wang, Gang Greg, Jeltsch, Albert, Song, Jikui

Volltext

Genetic correlates in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with Hyper-CVAD plus dasatinib or ponatinib von Sasaki, Yuya, Kantarjian, Hagop M., Short, Nicholas J., Wang, Feng, Furudate, Ken, Uryu, Hidetaka, Garris, Rebecca, Jain, Nitin, Sasaki, Koji, Ravandi, Farhad, Konopleva, Marina, Garcia-Manero, Guillermo, Little, Latasha, Gumbs, Curtis, Zhao, Li, Futreal, P. Andrew, Takahashi, Koichi, Jabbour, Elias

Volltext

Increased iron uptake by splenic hematopoietic stem cells promotes TET2-dependent erythroid regeneration von Tseng, Yu-Jung, Kageyama, Yuki, Murdaugh, Rebecca L., Kitano, Ayumi, Kim, Jong Hwan, Hoegenauer, Kevin A., Tiessen, Jonathan, Smith, Mackenzie H., Uryu, Hidetaka, Takahashi, Koichi, Martin, James F., Samee, Md Abul Hassan, Nakada, Daisuke

Volltext

SOD1 is a synthetic-lethal target in PPM1D -mutant leukemia cells von Zhang, Linda, Hsu, Joanne I, Braekeleer, Etienne D, Chen, Chun-Wei, Patel, Tajhal D, Martell, Alejandra G, Guzman, Anna G, Wohlan, Katharina, Waldvogel, Sarah M, Uryu, Hidetaka, Tovy, Ayala, Callen, Elsa, Murdaugh, Rebecca L, Richard, Rosemary, Jansen, Sandra, Vissers, Lisenka, de Vries, Bert B A, Nussenzweig, Andre, Huang, Shixia, Coarfa, Cristian, Anastas, Jamie, Takahashi, Koichi, Vassiliou, George, Goodell, Margaret A

Volltext

Correction: Genetic correlates in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with Hyper-CVAD plus dasatinib or ponatinib von Sasaki, Yuya, Kantarjian, Hagop M., Short, Nicholas J., Wang, Feng, Furudate, Ken, Uryu, Hidetaka, Garris, Rebecca, Jain, Nitin, Sasaki, Koji, Ravandi, Farhad, Konopleva, Marina, Garcia-Manero, Guillermo, Little, Latasha, Gumbs, Curtis, Zhao, Li, Futreal, P. Andrew, Takahashi, Koichi, Jabbour, Elias

Volltext

Synthetic retinoid Am80 ameliorates chronic graft-versus-host disease by down-regulating Th1 and Th17 von Nishimori, Hisakazu, Maeda, Yoshinobu, Teshima, Takanori, Sugiyama, Haruko, Kobayashi, Koichiro, Yamasuji, Yoshiko, Kadohisa, Sachiyo, Uryu, Hidetaka, Takeuchi, Kengo, Tanaka, Takehiro, Yoshino, Tadashi, Iwakura, Yoichiro, Tanimoto, Mitsune

Volltext

Automated urinary sediment detection for Fabry disease using deep-learning algorithms von Uryu, Hidetaka, Migita, Ohsuke, Ozawa, Minami, Kamijo, Chikako, Aoto, Saki, Okamura, Kohji, Hasegawa, Fuyuki, Okuyama, Torayuki, Kosuga, Motomichi, Hata, Kenichiro

Volltext

Breakthrough Trichosporonosis in Patients with Hematologic Malignancies Receiving Micafungin von Matsue, Kosei, Uryu, Hidetaka, Koseki, Mihoko, Asada, Noboru, Takeuchi, Masami

Volltext

Mutant Natural Killer Cell Dysfunction Enables the Immune Escape of Premalignant MDS Cell Clones von Ganan-Gomez, Irene, Kumar, Bijender, Rodriguez Sevilla, Juan Jose, Ma, Feiyang, Kim, Yi June, Chien, Kelly S., Nelson, Kate, Yang, Hui, Tan, Roselyn, Li, Zongrui, Tanaka, Tomoyuki, Uryu, Hidetaka, Kanagal-Shamanna, Rashmi, Loghavi, Sanam, Alatrash, Gheath, Bejar, Rafael, Rezvani, Katayoun, Takahashi, Koichi, Garcia-Manero, Guillermo, Daher, MD, May, Colla, Simona

Volltext

Genome-Wide CRISPR Screen Reveals Dependency of PPM1D-mutant Cells on DNA Repair von Zhang, Linda, Hsu, Joanne I., Braekeleer, Etienne D., Uryu, Hidetaka, Callen-Moreu, Elsa, Nussenzweig, Andre, Takahashi, Koichi, Vassiliou, George S, Goodell, Margaret A.

Volltext

P1330: CYTOREDUCTIVE CHEMOTHERAPY COULD ACCELERATE THE LOSS OF CLONAL DIVERSITY IN HEMATOPOIETIC STEM CELLS AND PROMOTES THE CONVERGENT EVOLUTION OF THERAPY‐RELATED CLONAL HEMATOPO... von Uryu, Hidetaka, Saeki, Koichi, Nangalia, Jyoti, Chapman, Michael, Zhao, LI, Hsu, Joanne, Bueso‐Ramos, Carlos, Chen, Shujuan, Yang, Hui, Dinardo, Courtney, Daver, Naval, Colla, Simona, Ganan‐Gomez, Irene, Zhang, Jianhua, Song, Xingzhi, Thompson, Erika, Tang, Hongli, Orlowski, Robert Z, Champlin, Richard E., Qazilbash, Muzaffar H., Shpall, Elizabeth J., Futreal, Andrew, Garcia‐Manero, Guillermo, Haeno, Hiroshi, Takahashi, Koichi

Volltext

SOD1 is a synthetic-lethal target in PPM1D-mutant leukemia cells von Zhang, Linda, Hsu, Joanne I, Braekeleer, Etienne D, Chen, Chun-Wei, Patel, Tajhal D, Martell, Alejandra G, Guzman, Anna G, Wohlan, Katharina, Waldvogel, Sarah M, Uryu, Hidetaka, Tovy, Ayala, Callen, Elsa, Murdaugh, Rebecca L, Richard, Rosemary, Jansen, Sandra, Vissers, Lisenka, de Vries, Bert BA, Nussenzweig, Andre, Huang, Shixia, Coarfa, Cristian, Anastas, Jamie, Takahashi, Koichi, Vassiliou, George, Goodell, Margaret A

Volltext

Abstract 1029: Epigenetic control of tumor-infiltrating lymphocyte metabolic-exhaustion von Koss, Brian, Shields, Bradley D., Taylor, Erin M., Storey, Aaron J., Byrum, Stephanie D., Gies, Allen J., Washam, Charity L., Choudhury, Samrat Roy, Ahn, Jeong Hyun, Uryu, Hidetaka, Krager, Kimberly J., Chiang, Tung-Chin, Mackintosh, Samuel G., Edmondson, Rick D., Aykin-Burns, Nukhet, Wang, Gang Greg, Tackett, Alan J.

Volltext

Phase separation drives aberrant chromatin looping and cancer development von Ahn, Jeong Hyun, Davis, Eric S., Daugird, Timothy A., Zhao, Shuai, Quiroga, Ivana Yoseli, Uryu, Hidetaka, Li, Jie, Storey, Aaron J., Tsai, Yi-Hsuan, Keeley, Daniel P., Mackintosh, Samuel G., Edmondson, Ricky D., Byrum, Stephanie D., Cai, Ling, Tackett, Alan J., Zheng, Deyou, Legant, Wesley R., Phanstiel, Douglas H., Wang, Gang Greg

Volltext

Graft-versus-host disease disrupts intestinal microbial ecology by inhibiting Paneth cell production of α-defensins von Eriguchi, Yoshihiro, Takashima, Shuichiro, Oka, Hideyo, Shimoji, Sonoko, Nakamura, Kiminori, Uryu, Hidetaka, Shimoda, Shinji, Iwasaki, Hiromi, Shimono, Nobuyuki, Ayabe, Tokiyoshi, Akashi, Koichi, Teshima, Takanori

Volltext

Successful Combined Use of Tranexamic Acid and Unfractionated Heparin for Life-Threatening Bleeding Associated with Intravascular Coagulation in a Patient with Chronic Myelogenous... von KOSEKI, Mihoko, ASADA, Noboru, URYU, Hidetaka, TAKEUCHI, Masami, ASAKURA, Hidesaku, MATSUE, Kosei

Volltext

Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic von Li, Dongxu, Yu, Xufen, Kottur, Jithesh, Gong, Weida, Zhang, Zhao, Storey, Aaron J., Tsai, Yi-Hsuan, Uryu, Hidetaka, Shen, Yudao, Byrum, Stephanie D., Edmondson, Rick D., Mackintosh, Samuel G., Cai, Ling, Liu, Zhijie, Aggarwal, Aneel K., Tackett, Alan J., Liu, Jing, Jin, Jian, Wang, Gang Greg

Volltext

Histone H3 proline 16 hydroxylation regulates mammalian gene expression von Liu, Xijuan, Wang, Jun, Boyer, Joshua A., Gong, Weida, Zhao, Shuai, Xie, Ling, Wu, Qiong, Zhang, Cheng, Jain, Kanishk, Guo, Yiran, Rodriguez, Javier, Li, Mingjie, Uryu, Hidetaka, Liao, Chengheng, Hu, Lianxin, Zhou, Jin, Shi, Xiaobing, Tsai, Yi-Hsuan, Yan, Qin, Luo, Weibo, Chen, Xian, Strahl, Brian D., von Kriegsheim, Alex, Zhang, Qi, Wang, Gang Greg, Baldwin, Albert S., Zhang, Qing

Volltext

Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity von Schwede, Matthew, Jahn, Katharina, Kuipers, Jack, Miles, Linde A., Bowman, Robert L., Robinson, Troy, Furudate, Ken, Uryu, Hidetaka, Tanaka, Tomoyuki, Sasaki, Yuya, Ediriwickrema, Asiri, Benard, Brooks, Gentles, Andrew J., Levine, Ross, Beerenwinkel, Niko, Takahashi, Koichi, Majeti, Ravindra

Volltext

Aggressive invasive micropapillary salivary duct carcinoma of the parotid gland von Yamamoto, Hidetaka, Uryu, Hideoki, Segawa, Yuichi, Tsuneyoshi, Masazumi

Volltext