Aneuploid senescent cells activate NF-κB to promote their immune clearance by NK cells von Wang, Ruoxi W, Viganò, Sonia, Ben-David, Uri, Amon, Angelika, Santaguida, Stefano

Volltext

Context is everything: aneuploidy in cancer von Ben-David, Uri, Amon, Angelika

Volltext

The tumorigenicity of human embryonic and induced pluripotent stem cells von Ben-David, Uri, Benvenisty, Nissim

Volltext

Elevated expression of ACE2 in tumor‐adjacent normal tissues of cancer patients von Winkler, Tom, Ben‐David, Uri

Volltext

Genomic evolution of cancer models: perils and opportunities von Ben-David, Uri, Beroukhim, Rameen, Golub, Todd R.

Volltext

High Prevalence of Evolutionarily Conserved and Species-Specific Genomic Aberrations in Mouse Pluripotent Stem Cells von Ben-David, Uri, Benvenisty, Nissim

Volltext

Integration of Genomic Data Enables Selective Discovery of Breast Cancer Drivers von Sanchez-Garcia, Félix, Villagrasa, Patricia, Matsui, Junji, Kotliar, Dylan, Castro, Verónica, Akavia, Uri-David, Chen, Bo-Juen, Saucedo-Cuevas, Laura, Rodriguez Barrueco, Ruth, Llobet-Navas, David, Silva, Jose M., Pe’er, Dana

Volltext

An Integrated Approach to Uncover Drivers of Cancer von Akavia, Uri David, Litvin, Oren, Kim, Jessica, Sanchez-Garcia, Felix, Kotliar, Dylan, Causton, Helen C., Pochanard, Panisa, Mozes, Eyal, Garraway, Levi A., Pe'er, Dana

Volltext

Large-Scale Analysis Reveals Acquisition of Lineage-Specific Chromosomal Aberrations in Human Adult Stem Cells von Ben-David, Uri, Mayshar, Yoav, Benvenisty, Nissim

Volltext

Immunologic and chemical targeting of the tight-junction protein Claudin-6 eliminates tumorigenic human pluripotent stem cells von Ben-David, Uri, Nudel, Neta, Benvenisty, Nissim

Volltext

DNA-based copy number analysis confirms genomic evolution of PDX models von Hoge, Anna C. H., Getz, Michal, Zimmer, Anat, Ko, Minjeong, Raz, Linoy, Beroukhim, Rameen, Golub, Todd R., Ha, Gavin, Ben-David, Uri

Volltext

Genetic and transcriptional evolution alters cancer cell line drug response von Ben-David, Uri, Siranosian, Benjamin, Ha, Gavin, Tang, Helen, Oren, Yaara, Hinohara, Kunihiko, Strathdee, Craig A., Dempster, Joshua, Lyons, Nicholas J., Burns, Robert, Nag, Anwesha, Kugener, Guillaume, Cimini, Beth, Tsvetkov, Peter, Maruvka, Yosef E., O’Rourke, Ryan, Garrity, Anthony, Tubelli, Andrew A., Bandopadhayay, Pratiti, Tsherniak, Aviad, Vazquez, Francisca, Wong, Bang, Birger, Chet, Ghandi, Mahmoud, Thorner, Aaron R., Bittker, Joshua A., Meyerson, Matthew, Getz, Gad, Beroukhim, Rameen, Golub, Todd R.

Volltext

Cas9 activates the p53 pathway and selects for p53-inactivating mutations von Enache, Oana M., Rendo, Veronica, Abdusamad, Mai, Lam, Daniel, Davison, Desiree, Pal, Sangita, Currimjee, Naomi, Hess, Julian, Pantel, Sasha, Nag, Anwesha, Thorner, Aaron R., Doench, John G., Vazquez, Francisca, Beroukhim, Rameen, Golub, Todd R., Ben-David, Uri

Volltext

Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy von Ippolito, Marica Rosaria, Martis, Valentino, Martin, Sara, Tijhuis, Andréa E., Hong, Christy, Wardenaar, René, Dumont, Marie, Zerbib, Johanna, Spierings, Diana C.J., Fachinetti, Daniele, Ben-David, Uri, Foijer, Floris, Santaguida, Stefano

Volltext

Chemical ablation of tumor-initiating human pluripotent stem cells von Ben-David, Uri, Benvenisty, Nissim

Volltext

Machine-learning analysis reveals an important role for negative selection in shaping cancer aneuploidy landscapes von Jubran, Juman, Slutsky, Rachel, Rozenblum, Nir, Rokach, Lior, Ben-David, Uri, Yeger-Lotem, Esti

Volltext

Identification and Classification of Chromosomal Aberrations in Human Induced Pluripotent Stem Cells von Mayshar, Yoav, Ben-David, Uri, Lavon, Neta, Biancotti, Juan-Carlos, Yakir, Benjamin, Clark, Amander T., Plath, Kathrin, Lowry, William E., Benvenisty, Nissim

Volltext

Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting von Aguirre, Andrew J, Meyers, Robin M, Weir, Barbara A, Vazquez, Francisca, Zhang, Cheng-Zhong, Ben-David, Uri, Cook, April, Ha, Gavin, Harrington, William F, Doshi, Mihir B, Kost-Alimova, Maria, Gill, Stanley, Xu, Han, Ali, Levi D, Jiang, Guozhi, Pantel, Sasha, Lee, Yenarae, Goodale, Amy, Cherniack, Andrew D, Oh, Coyin, Kryukov, Gregory, Cowley, Glenn S, Garraway, Levi A, Stegmaier, Kimberly, Roberts, Charles W, Golub, Todd R, Meyerson, Matthew, Root, David E, Tsherniak, Aviad, Hahn, William C

Volltext

Modulatory profiling identifies mechanisms of small molecule-induced cell death von Wolpaw, Adam J., Shimada, Kenichi, Skouta, Rachid, Welsch, Matthew E., Akavia, Uri David, Pe'er, Dana, Shaik, Fatima, Bulinski, J. Chloe, Stockwell, Brent R.

Volltext

Genomic Instability in Human Pluripotent Stem Cells Arises from Replicative Stress and Chromosome Condensation Defects von Lamm, Noa, Ben-David, Uri, Golan-Lev, Tamar, Storchová, Zuzana, Benvenisty, Nissim, Kerem, Batsheva

Volltext