Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity von Imaide, Satomi, Riching, Kristin M., Makukhin, Nikolai, Vetma, Vesna, Whitworth, Claire, Hughes, Scott J., Trainor, Nicole, Mahan, Sarah D., Murphy, Nancy, Cowan, Angus D., Chan, Kwok-Ho, Craigon, Conner, Testa, Andrea, Maniaci, Chiara, Urh, Marjeta, Daniels, Danette L., Ciulli, Alessio

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Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation von Gilan, Omer, Rioja, Inmaculada, Knezevic, Kathy, Bell, Matthew J, Yeung, Miriam M, Harker, Nicola R, Lam, Enid Y N, Chung, Chun-Wa, Bamborough, Paul, Petretich, Massimo, Urh, Marjeta, Atkinson, Stephen J, Bassil, Anna K, Roberts, Emma J, Vassiliadis, Dane, Burr, Marian L, Preston, Alex G S, Wellaway, Christopher, Werner, Thilo, Gray, James R, Michon, Anne-Marie, Gobbetti, Thomas, Kumar, Vinod, Soden, Peter E, Haynes, Andrea, Vappiani, Johanna, Tough, David F, Taylor, Simon, Dawson, Sarah-Jane, Bantscheff, Marcus, Lindon, Matthew, Drewes, Gerard, Demont, Emmanuel H, Daniels, Danette L, Grandi, Paola, Prinjha, Rab K, Dawson, Mark A

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A homogeneous bioluminescent immunoassay for parallel characterization of binding between a panel of antibodies and a family of Fcγ receptors von Nath, Nidhi, Godat, Becky, Flemming, Rod, Urh, Marjeta

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Development of NanoLuc bridging immunoassay for detection of anti-drug antibodies von Nath, Nidhi, Flemming, Rod, Godat, Becky, Urh, Marjeta

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TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS von Deplus, Rachel, Delatte, Benjamin, Schwinn, Marie K, Defrance, Matthieu, Méndez, Jacqui, Murphy, Nancy, Dawson, Mark A, Volkmar, Michael, Putmans, Pascale, Calonne, Emilie, Shih, Alan H, Levine, Ross L, Bernard, Olivier, Mercher, Thomas, Solary, Eric, Urh, Marjeta, Daniels, Danette L, Fuks, François

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Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy von Picaud, Sarah, Fedorov, Oleg, Thanasopoulou, Angeliki, Leonards, Katharina, Jones, Katherine, Meier, Julia, Olzscha, Heidi, Monteiro, Octovia, Martin, Sarah, Philpott, Martin, Tumber, Anthony, Filippakopoulos, Panagis, Yapp, Clarence, Wells, Christopher, Che, Ka Hing, Bannister, Andrew, Robson, Samuel, Kumar, Umesh, Parr, Nigel, Lee, Kevin, Lugo, Dave, Jeffrey, Philip, Taylor, Simon, Vecellio, Matteo L, Bountra, Chas, Brennan, Paul E, O'Mahony, Alison, Velichko, Sharlene, Müller, Susanne, Hay, Duncan, Daniels, Danette L, Urh, Marjeta, La Thangue, Nicholas B, Kouzarides, Tony, Prinjha, Rab, Schwaller, Jürg, Knapp, Stefan

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Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines von Nishiguchi, Gisele, Mascibroda, Lauren G., Young, Sarah M., Caine, Elizabeth A., Abdelhamed, Sherif, Kooijman, Jeffrey J., Miller, Darcie J., Das, Sourav, McGowan, Kevin, Mayasundari, Anand, Shi, Zhe, Barajas, Juan M., Hiltenbrand, Ryan, Aggarwal, Anup, Chang, Yunchao, Mishra, Vibhor, Narina, Shilpa, Thomas, Melvin, Loughran, Allister J., Kalathur, Ravi, Yu, Kaiwen, Zhou, Suiping, Wang, Xusheng, High, Anthony A., Peng, Junmin, Pruett-Miller, Shondra M., Daniels, Danette L., Urh, Marjeta, Shelat, Anang A., Mullighan, Charles G., Riching, Kristin M., Zaman, Guido J. R., Fischer, Marcus, Klco, Jeffery M., Rankovic, Zoran

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The TIP60 Complex Is a Conserved Coactivator of HIF1A von Perez-Perri, Joel I., Dengler, Veronica L., Audetat, K. Audrey, Pandey, Ahwan, Bonner, Elizabeth A., Urh, Marjeta, Mendez, Jacqui, Daniels, Danette L., Wappner, Pablo, Galbraith, Matthew D., Espinosa, Joaquín M.

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Build a Successful Career in Industry by Attaining Multidisciplinary Knowledge and Experience von Urh, Marjeta

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HaloTag-based purification of functional human kinases from mammalian cells von Ohana, Rachel Friedman, Hurst, Robin, Vidugiriene, Jolanta, Slater, Michael R., Wood, Keith V., Urh, Marjeta

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Deciphering the Interaction between Neonatal Fc Receptor and Antibodies Using a Homogeneous Bioluminescent Immunoassay von Nath, Nidhi, Godat, Becky, Flemming, Rod, Urh, Marjeta

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Development of no-wash, rapid Fcγ Receptor Binding Immunoassays using NanoBiT® Technology von Swanson, Brad, Nath, Nidhi, Godat, Becky, Flemming, Rod, Urh, Marjeta

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The importance of cellular degradation kinetics for understanding mechanisms in targeted protein degradation von Riching, Kristin M, Caine, Elizabeth A, Urh, Marjeta, Daniels, Danette L

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A functional analysis of the CREB signaling pathway using HaloCHIP-chip and high throughput reporter assays von Hartzell, Danette D, Trinklein, Nathan D, Mendez, Jacqui, Murphy, Nancy, Aldred, Shelley F, Wood, Keith, Urh, Marjeta

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Quantitative Live-Cell Kinetic Degradation and Mechanistic Profiling of PROTAC Mode of Action von Riching, Kristin M, Mahan, Sarah, Corona, Cesear R, McDougall, Mark, Vasta, James D, Robers, Matthew B, Urh, Marjeta, Daniels, Danette L

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Highly Efficient Protein and Complex Purification from Mammalian Cells Using the HaloTag® Technology von Méndez, Jacqui L, Ohana, Rachel Friedman, Hurst, Robin, Murphy, Nancy, Benink, Hélène, Slater, Michael R, Brueck, Chad, Daniels, Danette L, Urh, Marjeta

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Characterization and quantification of succinimide using peptide mapping under low-pH conditions and hydrophobic interaction chromatography von Cao, Mingyan, Mulagapati, Sri Hari Raju, Vemulapalli, Bhargavi, Wang, Jihong, Saveliev, Sergei V., Urh, Marjeta, Hunter, Alan, Liu, Dengfeng

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Abstract 5230: Real-time monitoring of PROTAC and molecular glue targeted degradation in living cells von Cosby, Neal C., Riching, Kristin M., Mahan, Sarah, Caine, Elizabeth A., Daniels, Danette L., Urh, Marjeta

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Modeling the CRL4A ligase complex to predict target protein ubiquitination induced by cereblon-recruiting PROTACs von Bai, Nan, Riching, Kristin M., Makaju, Aman, Wu, Hao, Acker, Timothy M., Ou, Shu-Ching, Zhang, Yaru, Shen, Xiaomeng, Bulloch, Daryl N., Rui, Huan, Gibson, Bradford W., Daniels, Danette L., Urh, Marjeta, Rock, Brooke M., Humphreys, Sara C.

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Addressing common challenges of biotherapeutic protein peptide mapping using recombinant trypsin von Menneteau, Thomas, Saveliev, Sergei, Butré, Claire I., Rivera, Alba Katiria González, Urh, Marjeta, Delobel, Arnaud

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