An Exome Sequencing Study to Assess the Role of Rare Genetic Variation in Pulmonary Fibrosis von Petrovski, Slavé, Todd, Jamie L, Durheim, Michael T, Wang, Quanli, Chien, Jason W, Kelly, Fran L, Frankel, Courtney, Mebane, Caroline M, Ren, Zhong, Bridgers, Joshua, Urban, Thomas J, Malone, Colin D, Finlen Copeland, Ashley, Brinkley, Christie, Allen, Andrew S, O'Riordan, Thomas, McHutchison, John G, Palmer, Scott M, Goldstein, David B

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Risk factors for development of cholestatic drug-induced liver injury: inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4 von Köck, Kathleen, Ferslew, Brian C, Netterberg, Ida, Yang, Kyunghee, Urban, Thomas J, Swaan, Peter W, Stewart, Paul W, Brouwer, Kim L R

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A genome-wide screen for variants influencing certolizumab pegol response in a moderate to severe rheumatoid arthritis population von White, Ian R, Kleinstein, Sarah E, Praet, Christophe, Chamberlain, Chris, McHale, Duncan, Maia, Jessica M, Xie, Pingxing, Goldstein, David B, Urban, Thomas J, Shea, Patrick R

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Variants in the ITPA Gene Protect Against Ribavirin-Induced Hemolytic Anemia and Decrease the Need for Ribavirin Dose Reduction von Thompson, Alexander J, Fellay, Jacques, Patel, Keyur, Tillmann, Hans L, Naggie, Susanna, Ge, Dongliang, Urban, Thomas J, Shianna, Kevin V, Muir, Andrew J, Fried, Michael W, Afdhal, Nezam H, Goldstein, David B, McHutchison, John G

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Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice von Church, Rachel J, Gatti, Daniel M, Urban, Thomas J, Long, Nanye, Yang, Xi, Shi, Qiang, Eaddy, J Scott, Mosedale, Merrie, Ballard, Shawn, Churchill, Gary A, Navarro, Victor, Watkins, Paul B, Threadgill, David W, Harrill, Alison H

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Inosine Triphosphate Protects Against Ribavirin-Induced Adenosine Triphosphate Loss by Adenylosuccinate Synthase Function von Hitomi, Yuki, Cirulli, Elizabeth T, Fellay, Jacques, McHutchison, John G, Thompson, Alexander J, Gumbs, Curtis E, Shianna, Kevin V, Urban, Thomas J, Goldstein, David B

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Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs von Urban, Thomas J, Shen, Yufeng, Stolz, Andrew, Chalasani, Naga, Fontana, Robert J, Rochon, James, Ge, Dongliang, Shianna, Kevin V, Daly, Ann K, Lucena, M Isabel, Nelson, Matthew R, Molokhia, Mariam, Aithal, Guruprasad P, Floratos, Aris, Pe’er, Itsik, Serrano, Jose, Bonkovsky, Herbert, Davern, Timothy J, Lee, William M, Navarro, Victor J, Talwalkar, Jayant A, Goldstein, David B, Watkins, Paul B

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A nonsense mutation in IKBKB causes combined immunodeficiency von Mousallem, Talal, Yang, Jialong, Urban, Thomas J., Wang, Hongxia, Adeli, Mehdi, Parrott, Roberta E., Roberts, Joseph L., Goldstein, David B., Buckley, Rebecca H., Zhong, Xiao-Ping

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Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin von Chen, Ying, Li, Shuanglian, Brown, Chaline, Cheatham, Stephen, Castro, Richard A, Leabman, Maya K, Urban, Thomas J, Chen, Ligong, Yee, Sook Wah, Choi, Ji Ha, Huang, Yong, Brett, Claire M, Burchard, Esteban G, Giacomini, Kathleen M

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Understanding human variation in infectious disease susceptibility through clinical and cellular GWAS von Ko, Dennis C, Urban, Thomas J

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Organic Anion Transporter 2 (SLC22A7) Is a Facilitative Transporter of cGMP von Cropp, Cheryl D., Komori, Takafumi, Shima, James E., Urban, Thomas J., Yee, Sook Wah, More, Swati S., Giacomini, Kathleen M.

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Clinical application of whole-genome sequencing in patients with primary immunodeficiency von Mousallem, Talal, MD, Urban, Thomas J., PharmD, PhD, McSweeney, K. Melodi, BS, Kleinstein, Sarah E., MS, Zhu, Mingfu, PhD, Adeli, Mehdi, MD, Parrott, Roberta E., BS, Roberts, Joseph L., MD, PhD, Krueger, Brian, PhD, Buckley, Rebecca H., MD, Goldstein, David B., PhD

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Features of Autoimmune Hepatitis in Patients With Drug-induced Liver Injury von de Boer, Ynto S, Kosinski, Andrzej S, Urban, Thomas J, Zhao, Zhen, Long, Nanye, Chalasani, Naga, Kleiner, David E, Hoofnagle, Jay H

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Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance von Ge, Dongliang, Fellay, Jacques, Thompson, Alexander J., Simon, Jason S., Shianna, Kevin V., Urban, Thomas J., Heinzen, Erin L., Qiu, Ping, Bertelsen, Arthur H., Muir, Andrew J., Sulkowski, Mark, McHutchison, John G., Goldstein, David B.

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Transport of drugs in the kidney by the human organic cation transporter, OCT2 and its genetic variants von Fujita, Tomoe, Urban, Thomas J., Leabman, Maya K., Fujita, Kazumi, Giacomini, Kathleen M.

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Functional Genetic Variation in the Basal Promoter of the Organic Cation/Carnitine Transporters OCTN1 (SLC22A4) and OCTN2 (SLC22A5) von Tahara, Harunobu, Yee, Sook Wah, Urban, Thomas J., Hesselson, Stephanie, Castro, Richard A., Kawamoto, Michiko, Stryke, Doug, Johns, Susan J., Ferrin, Thomas E., Kwok, Pui-Yan, Giacomini, Kathleen M.

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The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics von Erdman, Andrew R, Mangravite, Lara M, Urban, Thomas J, Lagpacan, Leah L, Castro, Richard A, de la Cruz, Melanie, Chan, Wendy, Huang, Conrad C, Johns, Susan J, Kawamoto, Michiko, Stryke, Douglas, Taylor, Travis R, Carlson, Elaine J, Ferrin, Thomas E, Brett, Claire M, Burchard, Esteban G, Giacomini, Kathleen M

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CYP2C91B Promoter Polymorphisms, in Linkage with CYP2C192, Affect Phenytoin Autoinduction of Clearance and Maintenance Dose von Chaudhry, Amarjit S., Urban, Thomas J., Lamba, Jatinder K., Birnbaum, Angela K., Remmel, Rory P., Subramanian, Murali, Strom, Stephen, You, Joyce H., Kasperaviciute, Dalia, Catarino, Claudia B., Radtke, Rodney A., Sisodiya, Sanjay M., Goldstein, David B., Schuetz, Erin G.

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IL28B genotype is associated with differential expression of intrahepatic interferon‐stimulated genes in patients with chronic hepatitis C von Urban, Thomas J., Thompson, Alexander J., Bradrick, Shelton S., Fellay, Jacques, Schuppan, Detlef, Cronin, Kenneth D., Hong, Linda, McKenzie, Alexander, Patel, Keyur, Shianna, Kevin V., McHutchison, John G., Goldstein, David B., Afdhal, Nezam

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ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C von Fellay, Jacques, Thompson, Alexander J., Ge, Dongliang, Gumbs, Curtis E., Urban, Thomas J., Shianna, Kevin V., Little, Latasha D., Qiu, Ping, Bertelsen, Arthur H., Watson, Mark, Warner, Amelia, Muir, Andrew J., Brass, Clifford, Albrecht, Janice, Sulkowski, Mark, McHutchison, John G., Goldstein, David B.

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