Temperature-Sensitive Substrate and Product Binding Underlie Temperature-Compensated Phosphorylation in the Clock von Shinohara, Yuta, Koyama, Yohei M., Ukai-Tadenuma, Maki, Hirokawa, Takatsugu, Kikuchi, Masaki, Yamada, Rikuhiro G., Ukai, Hideki, Fujishima, Hiroshi, Umehara, Takashi, Tainaka, Kazuki, Ueda, Hiroki R.

Volltext

Muscarinic Acetylcholine Receptors Chrm1 and Chrm3 Are Essential for REM Sleep von Niwa, Yasutaka, Kanda, Genki N., Yamada, Rikuhiro G., Shi, Shoi, Sunagawa, Genshiro A., Ukai-Tadenuma, Maki, Fujishima, Hiroshi, Matsumoto, Naomi, Masumoto, Koh-hei, Nagano, Mamoru, Kasukawa, Takeya, Galloway, James, Perrin, Dimitri, Shigeyoshi, Yasufumi, Ukai, Hideki, Kiyonari, Hiroshi, Sumiyama, Kenta, Ueda, Hiroki R.

Volltext

Production of knock-in mice in a single generation from embryonic stem cells von Ukai, Hideki, Kiyonari, Hiroshi, Ueda, Hiroki R

Volltext

Knockout-Rescue Embryonic Stem Cell-Derived Mouse Reveals Circadian-Period Control by Quality and Quantity of CRY1 von Ode, Koji L., Ukai, Hideki, Susaki, Etsuo A., Narumi, Ryohei, Matsumoto, Katsuhiko, Hara, Junko, Koide, Naoshi, Abe, Takaya, Kanemaki, Masato T., Kiyonari, Hiroshi, Ueda, Hiroki R.

Volltext

Mammalian Reverse Genetics without Crossing Reveals Nr3a as a Short-Sleeper Gene von Sunagawa, Genshiro A., Sumiyama, Kenta, Ukai-Tadenuma, Maki, Perrin, Dimitri, Fujishima, Hiroshi, Ukai, Hideki, Nishimura, Osamu, Shi, Shoi, Ohno, Rei-ichiro, Narumi, Ryohei, Shimizu, Yoshihiro, Tone, Daisuke, Ode, Koji L., Kuraku, Shigehiro, Ueda, Hiroki R.

Volltext

CKIε/δ-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock von Isojima, Yasushi, Nakajima, Masato, Ukai, Hideki, Fujishima, Hiroshi, Yamada, Rikuhiro G, Masumoto, Koh-hei, Kiuchi, Reiko, Ishida, Mayumi, Ukai-Tadenuma, Maki, Minami, Yoichi, Kito, Ryotaku, Nakao, Kazuki, Kishimoto, Wataru, Yoo, Seung-Hee, Shimomura, Kazuhiro, Takao, Toshifumi, Takano, Atsuko, Kojima, Toshio, Nagai, Katsuya, Sakaki, Yoshiyuki, Takahashi, Joseph S, Ueda, Hiroki R

Volltext

Cochlear Cell Modeling Using Disease-Specific iPSCs Unveils a Degenerative Phenotype and Suggests Treatments for Congenital Progressive Hearing Loss von Hosoya, Makoto, Fujioka, Masato, Sone, Takefumi, Okamoto, Satoshi, Akamatsu, Wado, Ukai, Hideki, Ueda, Hiroki R., Ogawa, Kaoru, Matsunaga, Tatsuo, Okano, Hideyuki

Volltext

Easy and efficient production of completely embryonic-stem-cell-derived mice using a micro-aggregation device von Sumiyama, Kenta, Matsumoto, Naomi, Garçon-Yoshida, Junko, Ukai, Hideki, Ueda, Hiroki R, Tanaka, Yo

Volltext

Rapid and easy-to-use ES cell manipulation device with a small groove near culturing wells von Funano, Shun-Ichi, Tone, Daisuke, Ukai, Hideki, Ueda, Hiroki R, Tanaka, Yo

Volltext

Generation of gene-corrected iPSCs line (KEIUi001-A) from a PARK8 patient iPSCs with familial Parkinson’s disease carrying the I2020T mutation in LRRK2 von Ohta, Etsuro, Sone, Takefumi, Ukai, Hideki, Hisamatsu, Tomoko, Kitagawa, Tokiko, Ishikawa, Mitsuru, Nagai, Makiko, Ueda, Hiroki R., Obata, Fumiya, Okano, Hideyuki

Volltext

Next-generation mammalian genetics toward organism-level systems biology von Susaki, Etsuo A., Ukai, Hideki, Ueda, Hiroki R.

Volltext

Systems biology of mammalian circadian clocks von Ukai, Hideki, Ueda, Hiroki R

Volltext

Whole-body imaging with single-cell resolution by tissue decolorization von Tainaka, Kazuki, Kubota, Shimpei I, Suyama, Takeru Q, Susaki, Etsuo A, Perrin, Dimitri, Ukai-Tadenuma, Maki, Ukai, Hideki, Ueda, Hiroki R

Volltext

Next-generation human genetics for organism-level systems biology von Ukai, Hideki, Sumiyama, Kenta, Ueda, Hiroki R

Volltext

Postsynaptic competition between calcineurin and PKA regulates mammalian sleep–wake cycles von Wang, Yimeng, Cao, Siyu, Tone, Daisuke, Fujishima, Hiroshi, Yamada, Rikuhiro G., Ohno, Rei-ichiro, Shi, Shoi, Matsuzawa, Kyoko, Yada, Saori, Kaneko, Mari, Sakamoto, Hirokazu, Onishi, Taichi, Ukai-Tadenuma, Maki, Ukai, Hideki, Hanashima, Carina, Hirose, Kenzo, Kiyonari, Hiroshi, Sumiyama, Kenta, Ode, Koji L., Ueda, Hiroki R.

Volltext

Distinct phosphorylation states of mammalian CaMKIIβ control the induction and maintenance of sleep von Tone, Daisuke, Ode, Koji L., Zhang, Qianhui, Fujishima, Hiroshi, Yamada, Rikuhiro G., Nagashima, Yoshiki, Matsumoto, Katsuhiko, Wen, Zhiqing, Yoshida, Shota Y., Mitani, Tomoki T., Arisato, Yuki, Ohno, Rei-ichiro, Ukai-Tadenuma, Maki, Yoshida Garçon, Junko, Kaneko, Mari, Shi, Shoi, Ukai, Hideki, Miyamichi, Kazunari, Okada, Takashi, Sumiyama, Kenta, Kiyonari, Hiroshi, Ueda, Hiroki R.

Volltext

Distinct phosphorylation states of mammalian CaMKII[beta] control the induction and maintenance of sleep von Tone, Daisuke, Ode, Koji L, Zhang, Qianhui, Fujishima, Hiroshi, Yamada, Rikuhiro G, Nagashima, Yoshiki, Matsumoto, Katsuhiko, Wen, Zhiqing, Yoshida, Shota Y, Mitani, Tomoki T, Arisato, Yuki, Ohno, Rei-ichiro, Ukai-Tadenuma, Maki, Yoshida Garçon, Junko, Kaneko, Mari, Shi, Shoi, Ukai, Hideki, Miyamichi, Kazunari, Okada, Takashi, Sumiyama, Kenta, Kiyonari, Hiroshi, Ueda, Hiroki R

Volltext

Distinct phosphorylation states of mammalian CaMKIIβ control the induction and maintenance of sleep von Daisuke Tone, Koji L. Ode, Qianhui Zhang, Hiroshi Fujishima, Rikuhiro G. Yamada, Yoshiki Nagashima, Katsuhiko Matsumoto, Zhiqing Wen, Shota Y. Yoshida, Tomoki T. Mitani, Yuki Arisato, Rei-ichiro Ohno, Maki Ukai-Tadenuma, Junko Yoshida Garçon, Mari Kaneko, Shoi Shi, Hideki Ukai, Kazunari Miyamichi, Takashi Okada, Kenta Sumiyama, Hiroshi Kiyonari, Hiroki R. Ueda

Volltext

JBIR-26, a Novel Natural Compound from Streptomyces sp. AK-AH76, Regulates Mammalian Circadian Clock von Izumikawa, Miho, Ukai, Hideki, Takagi, Motoki, Ueda, Hiroki R, Shin-ya, Kazuo

Volltext

Feedback repression is required for mammalian circadian clock function von Ueda, Hiroki R, Hogenesch, John B, Sato, Trey K, Yamada, Rikuhiro G, Ukai, Hideki, Baggs, Julie E, Miraglia, Loren J, Kobayashi, Tetsuya J, Welsh, David K, Kay, Steve A

Volltext