The SimpliciT1 Study: A Randomized, Double-Blind, Placebo-Controlled Phase 1b/2 Adaptive Study of TTP399, a Hepatoselective Glucokinase Activator, for Adjunctive Treatment of Type... von Klein, Klara R, Freeman, Jennifer L R, Dunn, Imogene, Dvergsten, Chris, Kirkman, M Sue, Buse, John B, Valcarce, Carmen

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SYNTHESIS AND SPECTRA OF SUBSTITUTED 9-CHLOROMETHYLENEXANTHENES, THEIR CORRESPONDING XANTHONES, AND RELATED MINOR PRODUCTS von MARTIN, NED H., CLARY, ROBERT T., FUDALA, LOUISE D., HYDE, RAYMOND G., JACKSON, E. PATRICK, UEHLING, JULIE M., O'CONNER, FREDERICK, PENNINGTON, GARY A., PINER, RICKY T., SYKES, DANNY P., WELLS, RICHARD A., WRIGHT, KELVIN W.

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Multicenter, Randomized Trial of a Bionic Pancreas in Type 1 Diabetes von Russell, Steven J, Beck, Roy W, Damiano, Edward R, El-Khatib, Firas H, Ruedy, Katrina J, Balliro, Courtney A, Li, Zoey, Calhoun, Peter, Wadwa, R Paul, Buckingham, Bruce, Zhou, Keren, Daniels, Mark, Raskin, Philip, White, Perrin C, Lynch, Jane, Pettus, Jeremy, Hirsch, Irl B, Goland, Robin, Buse, John B, Kruger, Davida, Mauras, Nelly, Muir, Andrew, McGill, Janet B, Cogen, Fran, Weissberg-Benchell, Jill, Sherwood, Jordan S, Castellanos, Luz E, Hillard, Mallory A, Tuffaha, Marwa, Putman, Melissa S, Sands, Mollie Y, Forlenza, Gregory, Slover, Robert, Messer, Laurel H, Cobry, Erin, Shah, Viral N, Polsky, Sarit, Lal, Rayhan, Ekhlaspour, Laya, Hughes, Michael S, Basina, Marina, Hatipoglu, Betul, Olansky, Leann, Bhangoo, Amrit, Forghani, Nikta, Kashmiri, Himala, Sutton, Francoise, Choudhary, Abha, Penn, Jimmy, Jafri, Rabab, Rayas, Maria, Escaname, Elia, Kerr, Catherine, Favela-Prezas, Ruby, Boeder, Schafer, Trikudanathan, Subbulaxmi, Williams, Kristen M, Leibel, Natasha, Kirkman, M Sue, Bergamo, Kate, Klein, Klara R, Dostou, Jean M, Machineni, Sriram, Young, Laura A, Diner, Jamie C, Bhan, Arti, Jones, J Kimberly, Benson, Matthew, Bird, Keisha, Englert, Kimberly, Permuy, Joe, Cossen, Kristina, Felner, Eric, Salam, Maamoun, Silverstein, Julie M, Adamson, Samantha, Cedeno, Andrea, Meighan, Seema, Dauber, Andrew

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Structure and mechanism of action of the hydroxy–aryl–aldehyde class of IRE1 endoribonuclease inhibitors von Sanches, Mario, Duffy, Nicole M., Talukdar, Manisha, Thevakumaran, Nero, Chiovitti, David, Canny, Marella D., Lee, Kenneth, Kurinov, Igor, Uehling, David, Al-awar, Rima, Poda, Gennadiy, Prakesch, Michael, Wilson, Brian, Tam, Victor, Schweitzer, Colleen, Toro, Andras, Lucas, Julie L., Vuga, Danka, Lehmann, Lynn, Durocher, Daniel, Zeng, Qingping, Patterson, John B., Sicheri, Frank

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Phenolic Lipids Derived from Cashew Nut Shell Liquid to Treat Metabolic Diseases von Sahin, Cigdem, Magomedova, Lilia, Ferreira, Thais A. M, Liu, Jiabao, Tiefenbach, Jens, Alves, Priscilla S, Queiroz, Fellipe J. G, Oliveira, Andressa S. de, Bhattacharyya, Mousumi, Grouleff, Julie, Nogueira, Patrícia C. N, Silveira, Edilberto R, Moreira, Daniel C, Leite, José Roberto Souza de Almeida, Brand, Guilherme D, Uehling, David, Poda, Gennady, Krause, Henry, Cummins, Carolyn L, Romeiro, Luiz A. S

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Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma von Smil, David, Wong, Jong Fu, Williams, Eleanor P, Adamson, Roslin J, Howarth, Alison, McLeod, David A, Mamai, Ahmed, Kim, Soyoung, Wilson, Brian J, Kiyota, Taira, Aman, Ahmed, Owen, Julie, Poda, Gennady, Horiuchi, Kurumi Y, Kuznetsova, Ekaterina, Ma, Haiching, Hamblin, J. Nicole, Cramp, Sue, Roberts, Owen G, Edwards, Aled M, Uehling, David, Al-awar, Rima, Bullock, Alex N, O’Meara, Jeff A, Isaac, Methvin B

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Synthesis and Antitumor Activity of Novel Water Soluble Derivatives of Camptothecin as Specific Inhibitors of Topoisomerase I von Luzzio, Michael J, Besterman, Jeffrey M, Emerson, David L, Evans, Michael G, Lackey, Karen, Leitner, Peter L, McIntyre, Gordon, Morton, Bradley, Myers, Peter L, Peel, Michael, Sisco, Jay M, Sternbach, Daniel D, Tong, Wei-Qin, Truesdale, Ann, Uehling, David E, Vuong, Alan, Yates, Julie

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Activin A receptor, type I (ACVR1); A Target Enabling Package von Williams, Eleanor, Adamson, Roslin J, Wong, Jong Fu, Howarth, Alison, Krojer, Tobias, Smil, David, McLeod, David A, Mamai, Ahmed, Soyoung Kim, Wilson, Brian J, Taira Kiyota, Aman, Ahmed, Owen, Julie, Poda, Gennady, Horiuchi, Kurumi Y, Kuznetsova, Ekaterina, Haiching Ma, J Nicole Hamblin, Cramp, Sue, Roberts, Owen G, Edwards, Aled M, Rooney, Lisa, Uehling, David, Al-Awar, Rima, O'Meara, Jeff A, Methvin B Isaac, Delft, Frank Von, Bullock, Alex N

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