A method for the generation of human stem cell-derived alpha cells von Peterson, Quinn P., Veres, Adrian, Chen, Lihua, Slama, Michael Q., Kenty, Jennifer H. R., Hassoun, Shaimaa, Brown, Matthew R., Dou, Haiqiang, Duffy, Caden D., Zhou, Quan, Matveyenko, Aleksey V., Tyrberg, Björn, Sörhede-Winzell, Maria, Rorsman, Patrik, Melton, Douglas A.

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Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling von Ghiasi, Seyed Mojtaba, Dahlby, Tina, Hede Andersen, Caroline, Haataja, Leena, Petersen, Sólrun, Omar-Hmeadi, Muhmmad, Yang, Mingyu, Pihl, Celina, Bresson, Sophie Emilie, Khilji, Muhammad Saad, Klindt, Kristian, Cheta, Oana, Perone, Marcelo J, Tyrberg, Björn, Prats, Clara, Barg, Sebastian, Tengholm, Anders, Arvan, Peter, Mandrup-Poulsen, Thomas, Marzec, Michal Tomasz

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Inhibition of the prostaglandin D2–GPR44/DP2 axis improves human islet survival and function von Abadpour, Shadab, Tyrberg, Björn, Schive, Simen W., Huldt, Charlotte Wennberg, Gennemark, Peter, Ryberg, Erik, Rydén-Bergsten, Tina, Smith, David M., Korsgren, Olle, Skrtic, Stanko, Scholz, Hanne, Winzell, Maria Sörhede

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Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats von Grunddal, Kaare V., Trammell, Samuel A. J., Bæch-Laursen, Cecilie, Andersen, Daniel B., Xu, Stella F. S., Andersen, Helle, Gillum, Matthew P., Ghiasi, Seyed M., Novak, Ivana, Tyrberg, Björn, Li, Chien, Rosenkilde, Mette M., Hartmann, Bolette, Holst, Jens J., Kuhre, Rune E.

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Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas von Hao, Ergeng, Tyrberg, Björn, Itkin-Ansari, Pamela, Lakey, Jonathan R T, Geron, Ifat, Monosov, Edward Z, Barcova, Maria, Mercola, Mark, Levine, Fred

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The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, low concentrations of interleukin 1 β von Khilji, Muhammad Saad, Verstappen, Danielle, Dahlby, Tina, Burstein Prause, Michala Cecilie, Pihl, Celina, Bresson, Sophie Emilie, Bryde, Tenna Holgersen, Keller Andersen, Phillip Alexander, Klindt, Kristian, Zivkovic, Dusan, Bousquet-Dubouch, Marie-Pierre, Tyrberg, Björn, Mandrup-Poulsen, Thomas, Marzec, Michal Tomasz

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Sweet taste receptor deficient mice have decreased adiposity and increased bone mass von Simon, Becky R, Learman, Brian S, Parlee, Sebastian D, Scheller, Erica L, Mori, Hiroyuki, Cawthorn, William P, Ning, Xiaomin, Krishnan, Venkatesh, Ma, Yanfei L, Tyrberg, Björn, MacDougald, Ormond A

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Long noncoding RNAs are dynamically regulated during β-cell mass expansion in mouse pregnancy and control β-cell proliferation in vitro von Sisino, Giorgia, Zhou, Alex-Xianghua, Dahr, Niklas, Sabirsh, Alan, Soundarapandian, Mangala M, Perera, Ranjan, Larsson-Lekholm, Erik, Magnone, Maria Chiara, Althage, Magnus, Tyrberg, Björn

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Sweet taste receptor signaling in beta cells mediates fructose-induced potentiation of glucose-stimulated insulin secretion von Kyriazis, George A, Soundarapandian, Mangala M, Tyrberg, Björn

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Saccharin Stimulates Insulin Secretion Dependent on Sweet Taste Receptor-Induced Activation of PLC Signaling Axis von Serrano, Joan, Meshram, Nishita N, Soundarapandian, Mangala M, Smith, Kathleen R, Mason, Carter, Brown, Ian S, Tyrberg, Björn, Kyriazis, George A

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Exploring the insulin secretory properties of the PGD2-GPR44/DP2 axis in vitro and in a randomized phase-1 trial of type 2 diabetes patients von Skrtic, Stanko, Tyrberg, Björn, Broberg, Malin, Ericsson, Hans, Schnecke, Volker, Kjaer, Magnus, Hompesch, Marcus, Andersson, Eva-Marie, Ryberg, Erik, Aivazidis, Alexander, Wennberg Huldt, Charlotte, Löfgren, Lars, Morrow, Linda, Parkinson, Joanna, Rydén-Bergsten, Tina, Watkins, Elaine, Sörhede Winzell, Maria

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Inhibition of SGLT2 Preserves Function and Promotes Proliferation of Human Islets Cells In Vivo in Diabetic Mice von Karlsson, Daniel, Ahnmark, Andrea, Sabirsh, Alan, Andréasson, Anne-Christine, Gennemark, Peter, Sandinge, Ann-Sofie, Chen, Lihua, Tyrberg, Björn, Lindén, Daniel, Sörhede Winzell, Maria

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The No-Go and Nonsense-Mediated RNA Decay Pathways are Regulated by Inflammatory Cytokines in Insulin-Producing Cells and Human Islets and Determine β-Cell Insulin Biosynthesis and... von Mojtaba Ghiasi, Seyed, Krogh, Nicolai, Tyrberg, Björn, Mandrup-Poulsen, Thomas

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Sweet Taste Receptors Regulate Basal Insulin Secretion and Contribute to Compensatory Insulin Hypersecretion During the Development of Diabetes in Male Mice von Kyriazis, George A, Smith, Kathleen R, Tyrberg, Björn, Hussain, Tania, Pratley, Richard E

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No direct effect of SGLT2 activity on glucagon secretion von Kuhre, Rune E., Ghiasi, Seyed M., Adriaenssens, Alice E., Wewer Albrechtsen, Nicolai J., Andersen, Daniel B., Aivazidis, Alexander, Chen, Lihua, Mandrup-Poulsen, Thomas, Ørskov, Cathrine, Gribble, Fiona M., Reimann, Frank, Wierup, Nils, Tyrberg, Björn, Holst, Jens J.

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The long noncoding RNA TUNAR modulates Wnt signaling and regulates human β-cell proliferation von Zhou, Alex-Xianghua, Mondal, Tanmoy, Tabish, Ali Mustafa, Abadpour, Shadab, Ericson, Elke, Smith, David M, Knöll, Ralph, Scholz, Hanne, Kanduri, Chandrasekhar, Tyrberg, Björn, Althage, Magnus

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T-cadherin (Cdh13) in association with pancreatic β-cell granules contributes to second phase insulin secretion von Tyrberg, Björn, Miles, Philip, Azizian, Krist T., Denzel, Martin S., Nieves, Maria L., Monosov, Edward Z., Levine, Fred, Ranscht, Barbara

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Regulation of the β-cell inflammasome and contribution to stress-induced cellular dysfunction and apoptosis von Ghiasi, Seyed Mojtaba, Dahllöf, Mattias Salling, Osmai, Yama, Osmai, Mirwais, Jakobsen, Kathrine Kronberg, Aivazidis, Alexander, Tyrberg, Björn, Perruzza, Lisa, Prause, Michala Cecilie Burstein, Christensen, Dan Ploug, Fog-Tonnesen, Morten, Lundh, Morten, Grassi, Fabio, Chatenoud, Lucienne, Mandrup-Poulsen, Thomas

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MCPIP1 is a novel link between diabetogenic conditions and impaired insulin secretory capacity von Tyka, Karolina, Jörns, Anne, Dunst, Alessia, Tang, Yadi, Bryde, Tenna Holgersen, Mehmeti, Ilir, Walentinsson, Anna, Marselli, Lorella, Cnop, Miriam, Tyrberg, Björn, Marzec, Michal T., Gurgul-Convey, Ewa

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c-Myc Controls Proliferation Versus Differentiation in Human Pancreatic Endocrine Cells von Demeterco, Carla, Itkin-Ansari, Pamela, Tyrberg, Björn, Ford, Lance P., Jarvis, Richard A., Levine, Fred

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