Report of the IWGT working group on strategies and interpretation of regulatory in vivo tests I. Increases in micronucleated bone marrow cells in rodents that do not indicate genot... von TWEATS, D. J, BLAKEY, D, TICE, R, HEFLICH, R. H, JACOBS, A, JACOBSEN, S. D, MORITA, T, NOHMI, T, O'DONOVAN, M. R, SASAKI, Y. F, SOFUNI, T

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Testing strategies in mutagenicity and genetic toxicology: An appraisal of the guidelines of the European Scientific Committee for Cosmetics and Non-Food Products for the evaluatio... von Kirkland, D.J., Henderson, L., Marzin, D., Müller, L., Parry, J.M., Speit, G., Tweats, D.J., Williams, G.M.

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Report of the IWGT working group on strategy/interpretation for regulatory in vivo tests II. Identification of in vivo-only positive compounds in the bone marrow micronucleus test von TWEATS, D. J, BLAKEY, D, TICE, R, HEFLICH, R. H, JACOBS, A, JACOBSEN, S. D, MORITA, T, NOHMI, T, O'DONOVAN, M. R, SASAKI, Y. F, SOFUNI, T

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The GreenScreen® genotoxicity assay: a screening validation programme von Cahill, P.A., Knight, A.W., Billinton, N., Barker, M.G., Walsh, L., Keenan, P.O., Williams, C.V., Tweats, D.J., Walmsley, R.M.

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An assessment of the utility of the yeast GreenScreen assay in pharmaceutical screening von Van Gompel, J., Woestenborghs, F., Beerens, D., Mackie, C., Cahill, P.A., Knight, A.W., Billinton, N., Tweats, D.J., Walmsley, R.M.

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An analysis of results from 305 compounds tested with the yeast RAD54-GFP genotoxicity assay (GreenScreen GC)—including relative predictivity of regulatory tests and rodent carcino... von Knight, Andrew W., Billinton, N., Cahill, P. A., Scott, A., Harvey, J. S., Roberts, K. J., Tweats, D. J., Keenan, P. O., Walmsley, R. M.

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Determination of genetic toxicity and potential carcinogenicity in vitro—challenges post the Seventh Amendment to the European Cosmetics Directive von Tweats, D.J., Scott, A.D., Westmoreland, C., Carmichael, P.L.

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Genotoxicity studies of gastric acid inhibiting drugs von Burlinson, B, Morriss, S.H, Gatehouse, D.G, Tweats, D.J, Ekman, Lars, Bolcsfoldi, George, Macdonald, James, Nicols, Warren

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Investigations into the induction of aneuploidy and polyploidy in mammalian cells by the anti-tussive agent noscapine hydrochloride von Gatehouse, D.G., Stemp, G., Pascoe, S., Wilcox, P., Hawker, J., Tweats, D.J.

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The Viracept-EMS case: Impact and outlook von Walker, Vernon E., Casciano, Daniel A., Tweats, David J.

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The preclinical toxicological evaluation of sumatriptan von Owen, K., Hartley, K., Tucker, ML, Parkinson, MM, Tweats, DJ, Jackson, MR

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Uptake of tritiated thymidine by cells of the rat gastric mucosa after exposure to loxtidine or omeprazole von Burlinson, B., Morriss, S., Gatehouse, D. G., Tweats, D. J., Jackson, M. R. M

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Further debate of testing strategies von Tweats, David J., Gatehouse, David G.

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Practical issues on the application of the GHS classification criteria for germ cell mutagens von Morita, Takeshi, Hayashi, Makoto, Nakajima, Madoka, Tanaka, Noriho, Tweats, David J., Morikawa, Kaoru, Sofuni, Toshio

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Interlaboratory assessment of the GreenScreen HC GADD45a-GFP genotoxicity screening assay: An enabling study for independent validation as an alternative method von Billinton, Nicholas, Hastwell, Paul W., Beerens, Dominiek, Birrell, Louise, Ellis, Patricia, Maskell, Sharon, Webster, Thomas W., Windebank, Sam, Woestenborghs, Filip, Lynch, Anthony M., Scott, Andrew D., Tweats, David J., van Gompel, Jacky, Rees, Robert W., Walmsley, Richard M.

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Studies of error-prone DNA repair in Escherichia coli K-12 and Ames Salmonella typhimurium strains using a model alkylating agent von Little, C.A., Tweats, D.J., Pinney, R.J.

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Relevance of plasmid pKM101-mediated mutagenicity in bacteria to genotoxicity in mammalian cells von Little, C.A., Tweats, D.J., Pinney, R.J.

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Investigations into the genotoxic potential of loxtidine, a long-acting H2-receptor antagonist von Gatehouse, D., Wedd, D.J., Paes, D., Delow, G., Burlinson, B., Pascoe, S., Brice, A., Stemp, G., Tweats, D.J.

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Monitoring the marine environment for mutagens von PARRY, J. M, TWEATS, D. J, AL-MOSSAWI, M. A. J

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A differential killing assay for mutagens and carcinogens based on an improved repair-deficient strain of Escherichia coli von Tweats, D.J., Green, Michael H.L., Muriel, W.J.

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