Novel Relaxin Receptor RXFP1 Agonist AZD3427 in the Treatment of Heart Failure: A Phase 1a/b, First-in-Human, Randomized, Single-Blind, Placebo-Controlled Study von Connolly, Kathleen, George, Richard, Omar, Sami, Matsson, Elin, Åstrand, Magnus, Althage, Magnus, Pettersen, Daniel, Mohamed, Esha, Fang, Kelly, Lima, Joao A C, Kujacic, Mirjana, Ödesjö, Helena, Turton, Michelle, Johannesson, Petra, Gabrielsen, Anders, Ufnal, Marcin

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Efficacy and safety of zibotentan and dapagliflozin in patients with chronic kidney disease: study design and baseline characteristics of the ZENITH-CKD trial von Heerspink, Hiddo J L, Greasley, Peter J, Ahlström, Christine, Althage, Magnus, Dwyer, Jamie P, Law, Gordon, Wijkmark, Emma, Lin, Min, Mercier, Anne-Kristina, Sunnåker, Mikael, Turton, Michelle, Wheeler, David C, Ambery, Philip

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Education on the move: A project in Belize von Campbell, Shanine, Turton, Michelle

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Stereotyping as a response strategy when faking personality questionnaires von Mahar, Doug, Coburn, Barbara, Griffin, Naomi, Hemeter, Francis, Potappel, Christine, Turton, Michelle, Mulgrew, Kate

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Efficacy and safety of zibotentan and dapagliflozin in patients with chronic kidney disease: study design and baseline characteristics of the ZENITH-CKD trial von Heerspink, Hiddo JL, Greasley, Peter J, Ahlström, Christine, Althage, Magnus, Dwyer, Jamie P, Law, Gordon, Wijkmark, Emma, Lin, Min, Mercier, Anne-Kristina, Sunnåker, Mikael, Turton, Michelle, Wheeler, David C, Ambery, Philip

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Examining diabetic heel ulcers through an ecological lens: microbial community dynamics associated with healing and infection von Sloan, Tim J, Turton, James C, Tyson, Jess, Musgrove, Alison, Fleming, Vicki M, Lister, Michelle M, Loose, Matthew W, Sockett, R Elizabeth, Diggle, Mathew, Game, Frances L, Jeffcoate, William

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Comparison of amitriptyline supplemented with pregabalin, pregabalin supplemented with amitriptyline, and duloxetine supplemented with pregabalin for the treatment of diabetic peri... von Tesfaye, Solomon, Sloan, Gordon, Petrie, Jennifer, White, David, Bradburn, Mike, Julious, Steven, Rajbhandari, Satyan, Sharma, Sanjeev, Rayman, Gerry, Gouni, Ravikanth, Alam, Uazman, Cooper, Cindy, Loban, Amanda, Sutherland, Katie, Glover, Rachel, Waterhouse, Simon, Turton, Emily, Horspool, Michelle, Gandhi, Rajiv, Maguire, Deirdre, Jude, Edward B, Ahmed, Syed H, Vas, Prashanth, Hariman, Christian, McDougall, Claire, Devers, Marion, Tsatlidis, Vasileios, Johnson, Martin, Rice, Andrew S C, Bouhassira, Didier, Bennett, David L, Selvarajah, Dinesh

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Estimation of Oral Disease Burden among Older Adults in LTC: A Scoping Review von Turton, Bathsheba, Alqunaybit, Gheed, Tembhe, Amrita, Qari, Alaa, Rawal, Kadambari, Mandel, Ernest, Calabrese, Joseph, Henshaw, Michelle

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Optimal pharmacotherapy pathway in adults with diabetic peripheral neuropathic pain: the OPTION-DM RCT von Tesfaye, Solomon, Sloan, Gordon, Petrie, Jennifer, White, David, Bradburn, Mike, Young, Tracey, Rajbhandari, Satyan, Sharma, Sanjeev, Rayman, Gerry, Gouni, Ravikanth, Alam, Uazman, Julious, Steven A, Cooper, Cindy, Loban, Amanda, Sutherland, Katie, Glover, Rachel, Waterhouse, Simon, Turton, Emily, Horspool, Michelle, Gandhi, Rajiv, Maguire, Deirdre, Jude, Edward, Ahmed, Syed Haris, Vas, Prashanth, Hariman, Christian, McDougall, Claire, Devers, Marion, Tsatlidis, Vasileios, Johnson, Martin, Bouhassira, Didier, Bennett, David L, Selvarajah, Dinesh

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Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer's Disease von Sassi, Celeste, Ridge, Perry G, Nalls, Michael A, Gibbs, Raphael, Ding, Jinhui, Lupton, Michelle K, Troakes, Claire, Lunnon, Katie, Al-Sarraj, Safa, Brown, Kristelle S, Medway, Christopher, Lord, Jenny, Turton, James, Morgan, Kevin, Powell, John F, Kauwe, John S, Cruchaga, Carlos, Bras, Jose, Goate, Alison M, Singleton, Andrew B, Guerreiro, Rita, Hardy, John

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Effectiveness of a symptom-clinic intervention delivered by general practitioners with an extended role for people with multiple and persistent physical symptoms in England: the Mu... von Burton, Christopher, Mooney, Cara, Sutton, Laura, White, David, Dawson, Jeremy, Neilson, Aileen R, Rowlands, Gillian, Thomas, Steve, Horspool, Michelle, Fryer, Kate, Greco, Monica, Sanders, Tom, Thomas, Ruth E, Cooper, Cindy, Turton, Emily, Waheed, Waquas, Woodward, Jonathan, Mallender, Ellen, Deary, Vincent

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Structured surveillance of Achromobacter, Pandoraea and Ralstonia species from patients in England with cystic fibrosis von Coward, Amy, Kenna, Dervla T.D., Woodford, Neil, Turton, Jane F., Armstrong, Malcolm, Auckland, Cressida, Bowler, Ian, Burns, Phillipa, Cargill, James, Carroll, Mary, Flight, William, Graver, Michelle, Green, Heather, Horner, Carolyne, Jones, Andrew, Jones, Andrew M., Jones, Graeme, Mayell, Sarah, Orendi, Jeorge, Perry, Audrey, Robb, Ali, Tucker, Natasha, Waine, David, Winstanley, Trevor, Withers, Nick

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Investigating the role of rare coding variability in Mendelian dementia genes ( APP , PSEN1 , PSEN2 , GRN , MAPT , and PRNP ) in late-onset Alzheimer's disease von Sassi, Celeste, Guerreiro, Rita, Gibbs, Raphael, Ding, Jinhui, Lupton, Michelle K, Troakes, Claire, Al-Sarraj, Safa, Niblock, Michael, Gallo, Jean-Marc, Adnan, Jihad, Killick, Richard, Brown, Kristelle S, Medway, Christopher, Lord, Jenny, Turton, James, Bras, Jose, Morgan, Kevin, Powell, John F, Singleton, Andrew, Hardy, John

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Missense variant in TREML2 protects against Alzheimer's disease von Benitez, Bruno A, Jin, Sheng Chih, Guerreiro, Rita, Graham, Rob, Lord, Jenny, Harold, Denise, Sims, Rebecca, Lambert, Jean-Charles, Gibbs, J. Raphael, Bras, Jose, Sassi, Celeste, Harari, Oscar, Bertelsen, Sarah, Lupton, Michelle K, Powell, John, Bellenguez, Celine, Brown, Kristelle, Medway, Christopher, Haddick, Patrick CG, van der Brug, Marcel P, Bhangale, Tushar, Ortmann, Ward, Behrens, Tim, Mayeux, Richard, Pericak-Vance, Margaret A, Farrer, Lindsay A, Schellenberg, Gerard D, Haines, Jonathan L, Turton, Jim, Braae, Anne, Barber, Imelda, Fagan, Anne M, Holtzman, David M, Morris, John C, Williams, Julie, Kauwe, John S.K, Amouyel, Philippe, Morgan, Kevin, Singleton, Andy, Hardy, John, Goate, Alison M, Cruchaga, Carlos

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Supporting physical activity through co-production in people with severe mental ill health (SPACES): protocol for a randomised controlled feasibility trial von Jones, Gareth, Bailey, Laura, Beeken, Rebecca J, Brady, Samantha, Cooper, Cindy, Copeland, Robert J, Crosland, Suzanne, Dawson, Sam, Faires, Matthew, Gilbody, Simon, Haynes, Holly, Hill, Andrew, Hillison, Emily, Horspool, Michelle, Lee, Ellen, Li, Jinshuo, Machaczek, Katarzyna K, Parrott, Steve, Quirk, Helen, Stubbs, Brendon, Tew, Garry A, Traviss-Turner, Gemma, Turton, Emily, Walker, Lauren, Walters, Stephen, Weich, Scott, Wildbore, Ellie, Peckham, Emily

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Dipeptidyl peptidase-1 inhibition in patients hospitalised with COVID-19: a multicentre, double-blind, randomised, parallel-group, placebo-controlled trial von Keir, Holly R, Long, Merete B, Abo-Leyah, Hani, Giam, Yan Hui, Vadiveloo, Thenmalar, Pembridge, Thomas, Hull, Rebecca C, Delgado, Lilia, Band, Margaret, McLaren-Neil, Fiona, Adamson, Simon, Lahnsteiner, Eva, Gilmour, Amy, Hughes, Chloe, New, Benjamin Jm, Connell, David, Dowey, Rebecca, Turton, Helena, Richardson, Hollian, Cassidy, Diane, Cooper, Jamie, Suntharalingam, Jay, Diwakar, Lavanya, Russell, Peter, Underwood, Jonathan, Hicks, Alexander, Dosanjh, Davinder Ps, Sage, Beth, Dhasmana, Devesh, Spears, Mark, Thompson, Aa Roger, Brightling, Christopher, Smith, Andrew, Patel, Manish, George, Jacob, Condliffe, Alison M, Shoemark, Amelia, MacLennan, Graeme, Chalmers, James D

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Exome sequencing identifies 2 novel presenilin 1 mutations (p.L166V and p.S230R) in British early-onset Alzheimer's disease von Sassi, Celeste, Guerreiro, Rita, Gibbs, Raphael, Ding, Jinhui, Lupton, Michelle K, Troakes, Claire, Lunnon, Katie, Al-Sarraj, Safa, Brown, Kristelle S, Medway, Chirstopher, Lord, Jenny, Turton, James, Mann, David, Snowden, Julie, Neary, David, Harris, Jeniffer, Bras, Jose, Morgan, Kevin, Powell, John F, Singleton, Andrew, Hardy, John

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ABCA7 p.G215S as potential protective factor for Alzheimer’s disease von Sassi, C, Nalls, M.A, Ridge, P.G, Gibbs, R, Ding, J, Lupton, M.K, Troakes, C, Lunnon, K, Al-Sarraj, S, Brown, K.S, Medway, C, Clement, N, Lord, J, Turton, J, Bras, J, Almeida, M.R, Holstege, H, Louwersheimer, E, van der Flier, W, Scheltens, P, Van Swieten, J.C, Santana, I, Oliveira, C, Morgan, K, Powell, J.F, Kauwe, J.S, Cruchaga, C, Goate, A.M, Singleton, A.B, Guerreiro, R, Hardy, J

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Abstract 1440: Identification of a novel EGFR sparing brain penetrant ErbB2 inhibitor with activity against oncogenic ErbB2 mutations von Chicarelli, Mark J, Bouhana, Karyn, Brizendine, Richard K., Cable, LouAnn, Crow, Michelle, Fell, Brad, Fischer, John, Fulton, Jennifer, Guarnieri, Anna, Jalluri, Ravi, Knox, Hailey, Koch, Keith A., Rieger, Rob, Robinson, John, Stunkard, Lee M., Sullivan, Francis, Turton, Roy, Winski, Shannon, Zhou, Yeyun

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Influence of coding variability in APP-A[beta] metabolism genes in sporadic Alzheimer's disease von Sassi, Celeste, Ridge, Perry G, Nalls, Michael A, Gibbs, Raphael, Ding, Jinhui, Lupton, Michelle K, Troakes, Claire, Lunnon, Katie, Al-Sarraj, Safa, Brown, Kristelle S, Medway, Christopher, Lord, Jenny, Turton, James, Morgan, Kevin, Powell, John F, Kauwe, John S, Cruchaga, Carlos, Bras, Jose, Goate, Alison M, Singleton, Andrew B, Guerreiro, Rita, Hardy, John

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