The Plant Defensin Ppdef1 Is a Novel Topical Treatment for Onychomycosis von van der Weerden, Nicole L, Parisi, Kathy, McKenna, James A, Hayes, Brigitte M, Harvey, Peta J, Quimbar, Pedro, Wevrett, Sean R, Veneer, Prem K, McCorkelle, Owen, Vasa, Shaily, Guarino, Rosemary, Poon, Simon, Gaspar, Yolanda M, Baker, Michael J, Craik, David J, Turner, Rob B, Brown, Marc B, Bleackley, Mark R, Anderson, Marilyn A

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Free radical facilitated damage of ungual keratin von Khengar, Rajeshree H., Brown, Marc B., Turner, Rob B., Traynor, Matthew J., Holt, Katherine B., Jones, Stuart A.

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Abolishment of morphology-based taxa and change to binomial species names: 2022 taxonomy update of the ICTV bacterial viruses subcommittee von Turner, Dann, Shkoporov, Andrey N., Lood, Cédric, Millard, Andrew D., Dutilh, Bas E., Alfenas-Zerbini, Poliane, van Zyl, Leonardo J., Aziz, Ramy K., Oksanen, Hanna M., Poranen, Minna M., Kropinski, Andrew M., Barylski, Jakub, Brister, J Rodney, Chanisvili, Nina, Edwards, Rob A., Enault, François, Gillis, Annika, Knezevic, Petar, Krupovic, Mart, Kurtböke, Ipek, Kushkina, Alla, Lavigne, Rob, Lehman, Susan, Lobocka, Malgorzata, Moraru, Cristina, Moreno Switt, Andrea, Morozova, Vera, Nakavuma, Jesca, Reyes Muñoz, Alejandro, Rūmnieks, Jānis, Sarkar, BL, Sullivan, Matthew B., Uchiyama, Jumpei, Wittmann, Johannes, Yigang, Tong, Adriaenssens, Evelien M.

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Prevention and treatment of low back pain: evidence, challenges, and promising directions von Foster, Nadine E, Anema, Johannes R, Cherkin, Dan, Chou, Roger, Cohen, Steven P, Gross, Douglas P, Ferreira, Paulo H, Fritz, Julie M, Koes, Bart W, Peul, Wilco, Turner, Judith A, Maher, Chris G, Buchbinder, Rachelle, Hartvigsen, Jan, Cherkin, Dan, Foster, Nadine E, Maher, Chris G, Underwood, Martin, van Tulder, Maurits, Anema, Johannes R, Chou, Roger, Cohen, Stephen P, Menezes Costa, Lucíola, Croft, Peter, Ferreira, Manuela, Ferreira, Paulo H, Fritz, Julie M, Genevay, Stéphane, Gross, Douglas P, Hancock, Mark J, Hoy, Damian, Karppinen, Jaro, Koes, Bart W, Kongsted, Alice, Louw, Quinette, Öberg, Birgitta, Peul, Wilco C, Pransky, Glenn, Schoene, Mark, Sieper, Joachim, Smeets, Rob J, Turner, Judith A, Woolf, Anthony

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Taxonomic assignment of uncultivated prokaryotic virus genomes is enabled by gene-sharing networks von Bin Jang, Ho, Bolduc, Benjamin, Zablocki, Olivier, Kuhn, Jens H., Roux, Simon, Adriaenssens, Evelien M., Brister, J. Rodney, Kropinski, Andrew M, Krupovic, Mart, Lavigne, Rob, Turner, Dann, Sullivan, Matthew B.

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An 800-million-solar-mass black hole in a significantly neutral Universe at a redshift of 7.5 von Bañados, Eduardo, Venemans, Bram P., Mazzucchelli, Chiara, Farina, Emanuele P., Walter, Fabian, Wang, Feige, Decarli, Roberto, Stern, Daniel, Fan, Xiaohui, Davies, Frederick B., Hennawi, Joseph F., Simcoe, Robert A., Turner, Monica L., Rix, Hans-Walter, Yang, Jinyi, Kelson, Daniel D., Rudie, Gwen C., Winters, Jan Martin

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Taxonomy of prokaryotic viruses: 2018-2019 update from the ICTV Bacterial and Archaeal Viruses Subcommittee von Adriaenssens, Evelien M., Sullivan, Matthew B., Knezevic, Petar, van Zyl, Leonardo J., Sarkar, B. L., Dutilh, Bas E., Alfenas-Zerbini, Poliane, Łobocka, Małgorzata, Tong, Yigang, Brister, James Rodney, Moreno Switt, Andrea I., Klumpp, Jochen, Aziz, Ramy Karam, Barylski, Jakub, Uchiyama, Jumpei, Edwards, Rob A., Kropinski, Andrew M., Petty, Nicola K., Clokie, Martha R. J., Kushkina, Alla I., Morozova, Vera V., Duffy, Siobain, Gillis, Annika, Rumnieks, Janis, Kurtböke, İpek, Chanishvili, Nina, Goodridge, Lawrence, Wittmann, Johannes, Lavigne, Rob, Jang, Ho Bin, Prangishvili, David, Enault, Francois, Turner, Dann, Poranen, Minna M., Oksanen, Hanna M., Krupovic, Mart

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Low back pain: a call for action von Buchbinder, Rachelle, van Tulder, Maurits, Öberg, Birgitta, Costa, Lucíola Menezes, Woolf, Anthony, Schoene, Mark, Croft, Peter, Buchbinder, Rachelle, Hartvigsen, Jan, Cherkin, Dan, Foster, Nadine E, Maher, Chris G, Underwood, Martin, van Tulder, Maurits, Anema, Johannes R, Chou, Roger, Cohen, Stephen P, Menezes Costa, Lucíola, Croft, Peter, Ferreira, Manuela, Ferreira, Paulo H, Fritz, Julie M, Genevay, Stéphane, Gross, Douglas P, Hancock, Mark J, Hoy, Damian, Karppinen, Jaro, Koes, Bart W, Kongsted, Alice, Louw, Quinette, Öberg, Birgitta, Peul, Wilco C, Pransky, Glenn, Schoene, Mark, Sieper, Joachim, Smeets, Rob J, Turner, Judith A, Woolf, Anthony

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A 52-Week Placebo-Controlled Trial of Evolocumab in Hyperlipidemia von Blom, Dirk J, Hala, Tomas, Bolognese, Michael, Lillestol, Michael J, Toth, Phillip D, Burgess, Lesley, Ceska, Richard, Roth, Eli, Koren, Michael J, Ballantyne, Christie M, Monsalvo, Maria Laura, Tsirtsonis, Kate, Kim, Jae B, Scott, Rob, Wasserman, Scott M, Stein, Evan A

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IL-33 Induces IL-13-Dependent Cutaneous Fibrosis von Rankin, Andrew L, Mumm, John B, Murphy, Erin, Turner, Scott, Yu, Ni, McClanahan, Terrill K, Bourne, Patricia A, Pierce, Robert H, Kastelein, Rob, Pflanz, Stefan

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Taxonomy of prokaryotic viruses: 2017 update from the ICTV Bacterial and Archaeal Viruses Subcommittee von Adriaenssens, Evelien M., Wittmann, Johannes, Kuhn, Jens H., Turner, Dann, Sullivan, Matthew B., Dutilh, Bas E., Jang, Ho Bin, van Zyl, Leonardo J., Klumpp, Jochen, Lobocka, Malgorzata, Moreno Switt, Andrea I., Rumnieks, Janis, Edwards, Robert A., Uchiyama, Jumpei, Alfenas-Zerbini, Poliane, Petty, Nicola K., Kropinski, Andrew M., Barylski, Jakub, Gillis, Annika, Clokie, Martha R. C., Prangishvili, David, Lavigne, Rob, Aziz, Ramy Karam, Duffy, Siobain, Krupovic, Mart, Poranen, Minna M., Knezevic, Petar, Enault, Francois, Tong, Yigang, Oksanen, Hanna M., Rodney Brister, J.

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Antipsychotic use and diagnosis of delirium in the intensive care unit von Swan, Joshua T, Fitousis, Kalliopi, Hall, Jeffrey B, Todd, S Rob, Turner, Krista L

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Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome von Nickerson, Michael L., Warren, Michelle B., Toro, Jorge R., Matrosova, Vera, Glenn, Gladys, Turner, Maria L., Duray, Paul, Merino, Maria, Choyke, Peter, Pavlovich, Christian P., Sharma, Nirmala, Walther, McClellan, Munroe, David, Hill, Rob, Maher, Eamonn, Greenberg, Cheryl, Lerman, Michael I., Linehan, W.Marston, Zbar, Berton, Schmidt, Laura S.

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Computed tomographic colonography versus colonoscopy for investigation of patients with symptoms suggestive of colorectal cancer (SIGGAR): a multicentre randomised trial von Atkin, Wendy, Prof, Dadswell, Edward, MSci, Wooldrage, Kate, MSc, Kralj-Hans, Ines, PhD, von Wagner, Christian, PhD, Edwards, Rob, PhD, Yao, Guiqing, PhD, Kay, Clive, Prof, Burling, David, FRCR, Faiz, Omar, FRCS, Teare, Julian, FRCP, Lilford, Richard J, Prof, Morton, Dion, Prof, Wardle, Jane, Prof, Halligan, Steve, Prof

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Exascale applications: skin in the game von Alexander, Francis, Almgren, Ann, Bell, John, Bhattacharjee, Amitava, Chen, Jacqueline, Colella, Phil, Daniel, David, DeSlippe, Jack, Diachin, Lori, Draeger, Erik, Dubey, Anshu, Dunning, Thom, Evans, Thomas, Foster, Ian, Francois, Marianne, Germann, Tim, Gordon, Mark, Habib, Salman, Halappanavar, Mahantesh, Hamilton, Steven, Hart, William, Henry Huang, Zhenyu, Hungerford, Aimee, Kasen, Daniel, Kent, Paul R C, Kolev, Tzanio, Kothe, Douglas B, Kronfeld, Andreas, Luo, Ye, Mackenzie, Paul, McCallen, David, Messer, Bronson, Mniszewski, Sue, Oehmen, Chris, Perazzo, Amedeo, Perez, Danny, Richards, David, Rider, William J, Rieben, Rob, Roche, Kenneth, Siegel, Andrew, Sprague, Michael, Steefel, Carl, Stevens, Rick, Syamlal, Madhava, Taylor, Mark, Turner, John, Vay, Jean-Luc, Voter, Artur F, Windus, Theresa L, Yelick, Katherine

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Air quality and mental health: evidence, challenges and future directions von Bhui, Kamaldeep, Newbury, Joanne B., Latham, Rachel M., Ucci, Marcella, Nasir, Zaheer A., Turner, Briony, O'Leary, Catherine, Fisher, Helen L., Marczylo, Emma, Douglas, Philippa, Stansfeld, Stephen, Jackson, Simon K., Tyrrel, Sean, Rzhetsky, Andrey, Kinnersley, Rob, Kumar, Prashant, Duchaine, Caroline, Coulon, Frederic

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Certain heterozygous variants in the kinase domain of the serine/threonine kinase NEK8 can cause an autosomal dominant form of polycystic kidney disease von Claus, Laura R., Chen, Chuan, Stallworth, Jennifer, Turner, Joshua L., Slaats, Gisela G., Mabillard, Holly, Senum, Sarah R., Srikanth, Sujata, Flanagan-Steet, Heather, Louie, Raymond J., Silver, Josh, Lerner-Ellis, Jordan, Morel, Chantal, Mighton, Chloe, Sleutels, Frank, van Slegtenhorst, Marjon, van Ham, Tjakko, Brooks, Alice S., Dorresteijn, Eiske M., Barakat, Tahsin Stefan, Dahan, Karin, Demoulin, Nathalie, Goffin, Eric Jean, Olinger, Eric, Arumugam, Prabhu, Bevers, Roel, Bleda, Marta, Boardman-Pretty, Freya, Boustred, Christopher R., Brittain, Helen, Caulfield, Mark J., Chan, Georgia C., Elgar, Greg, Fowler, Tom, Giess, Adam, Hamblin, Angela, Henderson, Shirley, Hubbard, Tim J.P., Jackson, Rob, Jones, Louise J., Kasperaviciute, Dalia, Kayikci, Melis, Kousathanas, Athanasios, Lahnstein, Lea, Leigh, Sarah E.A., Leong, Ivonne U.S., Lopez, Javier F., Maleady-Crowe, Fiona, McEntagart, Meriel, Minneci, Federico, Moutsianas, Loukas, Mueller, Michael, Need, Anna C., O’Donovan, Peter, Odhams, Chris A., Patch, Christine, Pereira, Mariana Buongermino, Perez-Gil, Daniel, Pullinger, John, Rahim, Tahrima, Rendon, Augusto, Rogers, Tim, Savage, Kevin, Sawant, Kushmita, Scott, Richard H., Siddiq, Afshan, Sieghart, Alexander, Smith, Samuel C., Sosinsky, Alona, Stuckey, Alexander, Tanguy, Mélanie, Taylor Tavares, Ana Lisa, Thomas, Ellen R.A., Thompson, Simon R., Tucci, Arianna, Welland, Matthew J., Williams, Eleanor, Witkowska, Katarzyna, Wood, Suzanne M., Larsen, Martin, Hertz, Jens Michael, Lilien, Marc R., Obeidová, Lena, Stone, Hillarey K., Kerecuk, Larissa, Gurgu, Mihai, Yousef Yengej, Fjodor A., Ammerlaan, Carola M.E., Rookmaaker, Maarten B., Hanna, Christian, Rogers, R. Curtis, Duran, Karen, Peters, Edith, Sayer, John A., van Haaften, Gijs, Harris, Peter C., Ling, Kun, Mason, Jennifer M., van Eerde, Albertien M., Steet, Richard

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Application of evidence-based methods to construct mechanism-driven chemical assessment frameworks von Hoffmann, Sebastian

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Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids von Ntalla, Ioanna, Chasman, Daniel I., Lim, Elise, Lu, Yingchang, Sim, Xueling, Huffman, Jennifer E., Bartz, Traci M., Manning, Alisa K., Tajuddin, Salman M., Graff, Mariaelisa, Divers, Jasmin, Hagemeijer, Yanick, Hsu, Fang-Chi, Komulainen, Pirjo, Matoba, Nana, Robino, Antonietta, Takeuchi, Fumihiko, van der Most, Peter J., Wang, Yajuan, Ware, Erin B., Wen, Wanqing, Zhang, Weihua, Afaq, Saima, Broeckel, Ulrich, Brown, Morris, Campbell, Archie, Canouil, Mickaël, Christensen, Kaare, Concas, Maria Pina, de Vries, Paul S., Eaton, Charles B., Forouhi, Nita G., Gandin, Ilaria, Gao, He, Giulianini, Franco, Gu, C. Charles, Harris, Tamara B., Heikkinen, Sami, Hirata, Makoto, Hixson, James E., Ikram, M. Arfan, Johnson, Craig, Jonas, Jost Bruno, Katsuya, Tomohiro, Kilpeläinen, Tuomas O., Koh, Woon-Puay, Kolcic, Ivana, Kritchevsky, Stephen B., Kubo, Michiaki, Kuusisto, Johanna, Lakka, Timo A., Liang, Jingjing, Lin, Shiow, Liu, Jianjun, Liu, Kiang, Luzzi, Anna, McKenzie, Colin A., Milani, Lili, Morris, Andrew P., Nauck, Matthias, North, Kari E., O’Connell, Jeffrey R., Pedersen, Nancy L., Raitakari, Olli T., Reiner, Alex P., Rich, Stephen S., Rosendaal, Frits R., Schmidt, Carsten O., Schreiner, Pamela J., Sidney, Stephen, Smith, Jennifer A., Snieder, Harold, Waldenberger, Melanie, Wang, Lan, Williams, Christine A., Yu, Caizheng, Yuan, Jian-Min, Becker, Diane M., Boehnke, Michael, Cooper, Richard S., Elliott, Paul, Farrall, Martin, Freedman, Barry I., Horta, Bernardo L., Oldehinkel, Albertine J., Shu, Xiao-Ou, Wang, Jun-Sing, Wareham, Nicholas J., Weir, David R., Wu, Tangchun, Zheng, Wei, Psaty, Bruce M., Ridker, Paul M., van Dam, Rob M., van Duijn, Cornelia M., Tai, E. Shyong, Franceschini, Nora, Rotter, Jerome I., Zhu, Xiaofeng, Munroe, Patricia B.

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Human leukocyte antigen alleles associate with COVID-19 vaccine immunogenicity and risk of breakthrough infection von Mentzer, Alexander J., O’Connor, Daniel, Bibi, Sagida, Chelysheva, Irina, Clutterbuck, Elizabeth A., Demissie, Tesfaye, Dinesh, Tanya, Edwards, Nick J., Felle, Sally, Feng, Shuo, Flaxman, Amy L., Karp-Tatham, Eleanor, Li, Grace, Liu, Xinxue, Marchevsky, Natalie, Godfrey, Leila, Makinson, Rebecca, Bull, Maireid B., Fowler, Jamie, Alamad, Bana, Malinauskas, Tomas, Chong, Amanda Y., Sanders, Katherine, Shaw, Robert H., Voysey, Merryn, Snape, Matthew D., Pollard, Andrew J., Lambe, Teresa, Knight, Julian C.

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