Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1⁻/⁻ mouse von Liu, Benny, Turley, Stephen D, Burns, Dennis K, Miller, Anna M, Repa, Joyce J, Dietschy, John M

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A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome von Buchovecky, Christie M, Turley, Stephen D, Brown, Hannah M, Kyle, Stephanie M, McDonald, Jeffrey G, Liu, Benny, Pieper, Andrew A, Huang, Wenhui, Katz, David M, Russell, David W, Shendure, Jay, Justice, Monica J

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Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease von Gylling, Helena, Plat, Jogchum, Turley, Stephen, Ginsberg, Henry N, Ellegård, Lars, Jessup, Wendy, Jones, Peter J, Lütjohann, Dieter, Maerz, Winfried, Masana, Luis, Silbernagel, Günther, Staels, Bart, Borén, Jan, Catapano, Alberico L, De Backer, Guy, Deanfield, John, Descamps, Olivier S, Kovanen, Petri T, Riccardi, Gabriele, Tokgözoglu, Lale, Chapman, M. John

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In memoriam: John M. Dietschy Sr., MD (1932–2020) von Turley, Stephen D., Horton, Jay D., Andersen, John M., Fordtran, John S.

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Cyclodextrin overcomes the transport defect in nearly every organ of NPC1 mice leading to excretion of sequestered cholesterol as bile acid von Liu, Benny, Ramirez, Charina M., Miller, Anna M., Repa, Joyce J., Turley, Stephen D., Dietschy, John M.

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Weekly Cyclodextrin Administration Normalizes Cholesterol Metabolism in Nearly Every Organ of the Niemann-Pick Type C1 Mouse and Markedly Prolongs Life von Ramirez, Charina M, Liu, Benny, Taylor, Anna M, Repa, Joyce J, Burns, Dennis K, Weinberg, Arthur G, Turley, Stephen D, Dietschy, John M

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Genetic variations and treatments that affect the lifespan of the NPC1 mouse von Liu, Benny, Li, Hao, Repa, Joyce J., Turley, Stephen D., Dietschy, John M.

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Knockout of the Cholesterol 24-Hydroxylase Gene in Mice Reveals a Brain-specific Mechanism of Cholesterol Turnover von Lund, Erik G, Xie, Chonglun, Kotti, Tiina, Turley, Stephen D, Dietschy, John M, Russell, David W

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Impact of loss of SOAT2 function on disease progression in the lysosomal acid lipase-deficient mouse von Lopez, Adam M., Chuang, Jen-Chieh, Turley, Stephen D.

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Unesterified cholesterol accumulation in late endosomes/lysosomes causes neurodegeneration and is prevented by driving cholesterol export from this compartment von Aqul, Amal, Liu, Benny, Ramirez, Charina M, Pieper, Andrew A, Estill, Sandi Jo, Burns, Dennis K, Liu, Bing, Repa, Joyce J, Turley, Stephen D, Dietschy, John M

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Suppression of brain cholesterol synthesis in male Mecp2-deficient mice is age dependent and not accompanied by a concurrent change in the rate of fatty acid synthesis von Lopez, Adam M, Chuang, Jen-Chieh, Posey, Kenneth S, Turley, Stephen D

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Quantitation of the rates of hepatic and intestinal cholesterol synthesis in lysosomal acid lipase-deficient mice before and during treatment with ezetimibe von Chuang, Jen-Chieh, Lopez, Adam M., Turley, Stephen D.

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Control of Cholesterol Turnover in the Mouse von Dietschy, John M., Turley, Stephen D.

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Molecular markers of brain cholesterol homeostasis are unchanged despite a smaller brain mass in a mouse model of cholesteryl ester storage disease von Aqul, Amal A., Ramirez, Charina M., Lopez, Adam M., Burns, Dennis K., Repa, Joyce J., Turley, Stephen D.

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Niemann-Pick C1-deficient mice lacking sterol O-acyltransferase 2 have less hepatic cholesterol entrapment and improved liver function von Lopez, Adam M, Jones, Ryan D, Repa, Joyce J, Turley, Stephen D

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Ontogenesis and Modulation of Intestinal Unesterified Cholesterol Sequestration in a Mouse Model of Niemann–Pick C1 Disease von Lopez, Adam M., Ramirez, Charina M., Taylor, Anna M., Jones, Ryan D., Repa, Joyce J., Turley, Stephen D.

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Liver X Receptor Activation Enhances Cholesterol Loss from the Brain, Decreases Neuroinflammation, and Increases Survival of the NPC1 Mouse von Repa, Joyce J, Li, Hao, Frank-Cannon, Tamy C, Valasek, Mark A, Turley, Stephen D, Tansey, Malu G, Dietschy, John M

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Deletion of sterol O-acyltransferase 2 (SOAT2) function in mice deficient in lysosomal acid lipase (LAL) dramatically reduces esterified cholesterol sequestration in the small inte... von Lopez, Adam M, Posey, Kenneth S, Turley, Stephen D

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Quantitative role of LAL, NPC2, and NPC1 in lysosomal cholesterol processing defined by genetic and pharmacological manipulations von Ramirez, Charina M., Liu, Benny, Aqul, Amal, Taylor, Anna M., Repa, Joyce J., Turley, Stephen D., Dietschy, John M.

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Measurement of Rates of Cholesterol and Fatty Acid Synthesis In Vivo Using Tritiated Water von Lopez, Adam M., Chuang, Jen-Chieh, Turley, Stephen D.

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