Deep learning based tissue analysis predicts outcome in colorectal cancer von Bychkov, Dmitrii, Linder, Nina, Turkki, Riku, Nordling, Stig, Kovanen, Panu E., Verrill, Clare, Walliander, Margarita, Lundin, Mikael, Haglund, Caj, Lundin, Johan

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Repeated intratumoral administration of ONCOS-102 leads to systemic antitumor CD8 + T-cell response and robust cellular and transcriptional immune activation at tumor site in a pat... von Vassilev, L, Ranki, T, Joensuu, T, Jäger, E, Karbach, J, Wahle, C, Partanen, K, Kairemo, K, Alanko, T, Turkki, R, Linder, N, Lundin, J, Ristimäki, A, Kankainen, M, Hemminki, A, Backman, C, Dienel, K, von Euler, M, Haavisto, E, Hakonen, T, Juhila, J, Jäderberg, M, Priha, P, Vuolanto, A, Pesonen, S

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Precision systems medicine in urological Tumors – Molecular profiling and functional testing von Saeed, K., Ojamies, P., Pellinen, T., Rahkama, V., Eldfors, S., Paavolainen, L., Turkki, R., Horvath, P., Lundin, J., Nisen, H., af Hällström, T.M., Rannikko, A., Mirtti, T., Kallioniemi, O., Östling, P.

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683: Ex vivo modelling of Kras-driven murine non-small cell lung cancer von Närhi, K, Parri, E, Nagaraj, A, Kovanen, P, Turkki, R, Schoonenberg, A, Brenner, O, Kaustio, M, Blom, S, Verschuren, E

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136 Tumor-infiltrating lymphocytes (TILs) following intratumoral administration of ONCOS-102 are associated with prolonged overall survival in last line solid tumor patients von Pesonen, S, Joensuu, T, Jager, E, Karbach, J, Wahle, C, Kairemo, K, Partanen, K, Turkki, R, Hemminki, A, Backman, C, von Euler, M, Hakonen, T, Ranki, T, Vassilev, L, Vuolanto, A, Jaderberg, M

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Immune cell constitution in bone marrow microenvironment predicts outcome in adult ALL von Hohtari, Helena, Brück, Oscar, Blom, Sami, Turkki, Riku, Sinisalo, Marjatta, Kovanen, Panu E., Kallioniemi, Olli, Pellinen, Teijo, Porkka, Kimmo, Mustjoki, Satu

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Breast cancer outcome prediction with tumour tissue images and machine learning von Turkki, Riku, Byckhov, Dmitrii, Lundin, Mikael, Isola, Jorma, Nordling, Stig, Kovanen, Panu E., Verrill, Clare, von Smitten, Karl, Joensuu, Heikki, Lundin, Johan, Linder, Nina

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Systems pathology by multiplexed immunohistochemistry and whole-slide digital image analysis von Blom, Sami, Paavolainen, Lassi, Bychkov, Dmitrii, Turkki, Riku, Mäki-Teeri, Petra, Hemmes, Annabrita, Välimäki, Katja, Lundin, Johan, Kallioniemi, Olli, Pellinen, Teijo

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A malaria diagnostic tool based on computer vision screening and visualization of Plasmodium falciparum candidate areas in digitized blood smears von Linder, Nina, Turkki, Riku, Walliander, Margarita, Mårtensson, Andreas, Diwan, Vinod, Rahtu, Esa, Pietikäinen, Matti, Lundin, Mikael, Lundin, Johan

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Immune cell contexture in the bone marrow tumor microenvironment impacts therapy response in CML von Brück, Oscar, Blom, Sami, Dufva, Olli, Turkki, Riku, Chheda, Himanshu, Ribeiro, Antonio, Kovanen, Panu, Aittokallio, Tero, Koskenvesa, Perttu, Kallioniemi, Olli, Porkka, Kimmo, Pellinen, Teijo, Mustjoki, Satu

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CDX2 Loss With Microsatellite Stable Phenotype Predicts Poor Clinical Outcome in Stage II Colorectal Carcinoma von Slik, K, Turkki, R, Carpen, O, Kurki, S, Korkeila, E, Sundstrom, J, Pellinen, T

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Identification of tumor epithelium and stroma in tissue microarrays using texture analysis von Linder, Nina, Konsti, Juho, Turkki, Riku, Rahtu, Esa, Lundin, Mikael, Nordling, Stig, Haglund, Caj, Ahonen, Timo, Pietikäinen, Matti, Lundin, Johan

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Clonal heterogeneity influences drug responsiveness in renal cancer assessed by ex vivo drug testing of multiple patient‐derived cancer cells von Saeed, Khalid, Ojamies, Poojitha, Pellinen, Teijo, Eldfors, Samuli, Turkki, Riku, Lundin, Johan, Järvinen, Petrus, Nisen, Harry, Taari, Kimmo, af Hällström, Taija M., Rannikko, Antti, Mirtti, Tuomas, Kallioniemi, Olli, Östling, Päivi

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Antibody-supervised deep learning for quantification of tumor-infiltrating immune cells in hematoxylin and eosin stained breast cancer samples von Turkki, Riku, Linder, Nina, Kovanen, Panu E., Pellinen, Teijo, Lundin, Johan

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ITGB1-dependent upregulation of Caveolin-1 switches TGFβ signalling from tumour-suppressive to oncogenic in prostate cancer von Pellinen, Teijo, Blom, Sami, Sánchez, Sara, Välimäki, Katja, Mpindi, John-Patrick, Azegrouz, Hind, Strippoli, Raffaele, Nieto, Raquel, Vitón, Mariano, Palacios, Irene, Turkki, Riku, Wang, Yinhai, Sánchez-Alvarez, Miguel, Nordling, Stig, Bützow, Anna, Mirtti, Tuomas, Rannikko, Antti, Montoya, María C., Kallioniemi, Olli, del Pozo, Miguel A.

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Immunological data from cancer patients treated with Ad5/3-E2F-Δ24-GMCSF suggests utility for tumor immunotherapy von Hemminki, Otto, Parviainen, Suvi, Juhila, Juuso, Turkki, Riku, Linder, Nina, Lundin, Johan, Kankainen, Matti, Ristimäki, Ari, Koski, Anniina, Liikanen, Ilkka, Oksanen, Minna, Nettelbeck, Dirk M, Kairemo, Kalevi, Partanen, Kaarina, Joensuu, Timo, Kanerva, Anna, Hemminki, Akseli

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Quantification of Estrogen Receptor-Alpha Expression in Human Breast Carcinomas With a Miniaturized, Low-Cost Digital Microscope: A Comparison with a High-End Whole Slide-Scanner von Holmström, Oscar, Linder, Nina, Lundin, Mikael, Moilanen, Hannu, Suutala, Antti, Turkki, Riku, Joensuu, Heikki, Isola, Jorma, Diwan, Vinod, Lundin, Johan

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Spatial aspects of oncogenic signalling determine the response to combination therapy in slice explants from Kras‐driven lung tumours von Närhi, Katja, Nagaraj, Ashwini S, Parri, Elina, Turkki, Riku, van Duijn, Petra W, Hemmes, Annabrita, Lahtela, Jenni, Uotinen, Virva, Mäyränpää, Mikko I, Salmenkivi, Kaisa, Räsänen, Jari, Linder, Nina, Trapman, Jan, Rannikko, Antti, Kallioniemi, Olli, Af Hällström, Taija M, Lundin, Johan, Sommergruber, Wolfgang, Anders, Simon, Verschuren, Emmy W

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862P Prognostic role of CD3, CD4, CD8 and FOXP3 positive populations in early-stage endometrial carcinoma von Heredia Soto, V., Pellinen, T., Turkki, R., Ramón Patiño, J.L., Ruz-Caracuel, I., García de la Calle, L.E., López Janeiro, Á., Escudero, F.J., Miguel, M., Crespo, R., Ruiz, P., Peláez-García, A., Hardisson, D., Redondo, A., Mendiola, M.

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Immune profiles in acute myeloid leukemia bone marrow associate with patient age, T-cell receptor clonality, and survival von Brück, Oscar, Dufva, Olli, Hohtari, Helena, Blom, Sami, Turkki, Riku, Ilander, Mette, Kovanen, Panu, Pallaud, Celine, Ramos, Pedro Marques, Lähteenmäki, Hanna, Välimäki, Katja, El Missiry, Mohamed, Ribeiro, Antonio, Kallioniemi, Olli, Porkka, Kimmo, Pellinen, Teijo, Mustjoki, Satu

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