Abstract 1059: Paricalcitol, hydroxychloroquine and gemcitabine promote antitumor effects and modulate immune profile in pancreatic ductal adenocarcinoma von Ganji, Purnachandra Nagaraju, Thomas, Beena Elizabeth, Phillips, Maggie, Herting, Cameron, Ruggieri, Amanda, Keilson, Jessica Millian, Turgeon, Michael Kim, Saraswatula, Sisira, Pilcher, William, Lesinski, Gregory B., Bhasin, Manoj, El-Rayes, Bassel F.

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Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis von Verret, Michael, Lauzier, François, Zarychanski, Ryan, Perron, Caroline, Savard, Xavier, Pinard, Anne-Marie, Leblanc, Guillaume, Cossi, Marie-Joëlle, Neveu, Xavier, Turgeon, Alexis F., McAuley, Al, Flexman, Alana, Denault, André Y., Jerath, Angela, Prabhakar, Christopher, McCartney, Colin, Sawchuk, Corey, Yarnold, Cynthia, Boyle, David, Mazer, David, Roach, David, Tran, Diem, McKeen, Dolores, Yee, Doreen, Wijeysundera, Duminda, Belley-Côté, Emilie, Jacobsohn, Eric, de Médicis, Étienne, Carrier, Francois M., Hare, Greg, Bryson, Gregory, Grocott, Hilary, Yang, Homer, McVicar, Jason, O’Brien, Jennifer, Spence, Jessica, Kim, Jim, Murkin, John, Gamble, Jonathan, Sparrow, Kathryn, Wong, Kim, McCluskey, Stuart, Bautista, Michael, Law, Michael, Schmidt, Michael, Edwards, Nicola, Choi, Peter, Richebe, Philippe, Beaulieu, Pierre, Sondekoppam, Rakesh, Arellano, Ramiro, Dhawan, Richa, Hall, Richard, Ree, Ron, George, Ronald, Chun, Rosaleen, Brudney, Scott, Kowalski, Stephen, Syed, Summer, Sidhu, Surita, Saha, Tarit, Mutter, Thomas, Uppal, Vishal

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A minimal common outcome measure set for COVID-19 clinical research von Marshall, John C, Murthy, Srinivas, Diaz, Janet, Adhikari, N K, Angus, Derek C, Arabi, Yaseen M, Baillie, Kenneth, Bauer, Michael, Berry, Scott, Blackwood, Bronagh, Bonten, Marc, Bozza, Fernando, Brunkhorst, Frank, Cheng, Allen, Clarke, Mike, Dat, Vu Quoc, de Jong, Menno, Denholm, Justin, Derde, Lennie, Dunning, Jake, Feng, Xiaobin, Fletcher, Tom, Foster, Nadine, Fowler, Rob, Gobat, Nina, Gomersall, Charles, Gordon, Anthony, Glueck, Thomas, Harhay, Michael, Hodgson, Carol, Horby, Peter, Kim, YaeJean, Kojan, Richard, Kumar, Bharath, Laffey, John, Malvey, Denis, Martin-Loeches, Ignacio, McArthur, Colin, McAuley, Danny, McBride, Stephen, McGuinness, Shay, Merson, Laura, Morpeth, Susan, Needham, Dale, Netea, Mihai, Oh, Myoung-Don, Phyu, Sabai, Piva, Simone, Qiu, Ruijin, Salisu-Kabara, Halima, Shi, Lei, Shimizu, Naoki, Sinclair, Jorge, Tong, Steven, Turgeon, Alexis, Uyeki, Tim, van de Veerdonk, Frank, Webb, Steve, Williamson, Paula, Wolf, Timo, Zhang, Junhua

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Cerebral Oximetry Monitoring to Maintain Normal Cerebral Oxygen Saturation during High-risk Cardiac Surgery: A Randomized Controlled Feasibility Trial von Deschamps, Alain, Hall, Richard, Grocott, Hilary, Mazer, C David, Choi, Peter T, Turgeon, Alexis F, de Medicis, Etienne, Bussières, Jean S, Hudson, Christopher, Syed, Summer, Seal, Doug, Herd, Stuart, Lambert, Jean, Denault, André, Deschamps, Alain, Mutch, Alan, Turgeon, Alexis, Jerath, Angela, Fayad, Ashraf, Finnegan, Barry, Kent, Blaine, Kennedy, Brent, Cuthbertson, Brian H, Kavanagh, Brian, Warriner, Brian, Fudorow, Christine, McCartney, Colin, McIsaac, Dan, Dubois, Daniel, Campbell, David, Mazer, David, Neilpovitz, David, Rosen, David, Cheng, Davy, Drapeau, Dennis, Dillane, Derek, Tran, Diem, Mckeen, Dolores, Jacobsohn, Eric, Couture, Etienne, Alam, Fahad, Abdallah, Faraj, Ralley, Fiona E, Chung, Frances, Lellouche, Francois, Dobson, Gary, Germain, Genevieve, Djaiani, George, Gilron, Ian, Hare, Gregory, Bryson, Gregory, Clarke, Hance, McDonald, Heather, Roman-Smith, Helen, Yang, Homer, Douketis, James, Paul, James, Beaubien, Jean, Bussières, Jean, Pridham, Jeremy, Armstrong, J N, Parlow, Joel, Murkin, John, Gamble, Jonathan, Duttchen, Kaylene, Karkouti, Keyvan, Turner, Kim, Baghirzada, Leyla, Szabo, Linda, Lalu, Manoj, Wasowicz, Marcin, Bautista, Michael, Jacka, Michael, Murphy, Michael, Schmidt, Michael, Verret, Michaël, Perrault, Michel-Antoine, Beaudet, Nicolas, Buckley, Norman, Choi, Peter, MacDougall, Peter, Jones, Philip, Drolet, Pierre, Taneja, Ravi, Martin, Rene, George, Ronald, Chun, Rosa, McMullen, Sarah, Beattie, Scott, Sampson, Sonia, Choi, Stephen, Kowalski, Stephen, McCluskey, Stuart, Boet, Sylvain, Ramsay, Tim, Saha, Tarit, Mutter, Thomas, Chowdhury, Tumul, Uppal, Vishal, Mckay, William

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Calcium-induced differentiation in normal human colonoid cultures: Cell-cell / cell-matrix adhesion, barrier formation and tissue integrity von Attili, Durga, McClintock, Shannon D, Rizvi, Areeba H, Pandya, Shailja, Rehman, Humza, Nadeem, Daniyal M, Richter, Aliah, Thomas, Dafydd, Dame, Michael K, Turgeon, Danielle Kim, Varani, James, Aslam, Muhammad N

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Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: a randomized placebo-controlled, double-blind trial von Meyskens, Jr, Frank L, McLaren, Christine E, Pelot, Daniel, Fujikawa-Brooks, Sharon, Carpenter, Philip M, Hawk, Ernest, Kelloff, Gary, Lawson, Michael J, Kidao, Jayashri, McCracken, John, Albers, C Gregory, Ahnen, Dennis J, Turgeon, D Kim, Goldschmid, Steven, Lance, Peter, Hagedorn, Curt H, Gillen, Daniel L, Gerner, Eugene W

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Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19 von Goligher, Ewan C, Bradbury, Charlotte A, McVerry, Bryan J, Lawler, Patrick R, Berger, Jeffrey S, Gong, Michelle N, Carrier, Marc, Reynolds, Harmony R, Kumar, Anand, Turgeon, Alexis F, Kornblith, Lucy Z, Kahn, Susan R, Marshall, John C, Kim, Keri S, Houston, Brett L, Derde, Lennie P G, Cushman, Mary, Tritschler, Tobias, Angus, Derek C, Godoy, Lucas C, McQuilten, Zoe, Kirwan, Bridget-Anne, Farkouh, Michael E, Brooks, Maria M, Lewis, Roger J, Berry, Lindsay R, Lorenzi, Elizabeth, Gordon, Anthony C, Ahuja, Tania, Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M, Aryal, Diptesh, Baumann Kreuziger, Lisa, Beane, Abi, Bhimani, Zahra, Bihari, Shailesh, Billett, Henny H, Bond, Lindsay, Bonten, Marc, Brunkhorst, Frank, Buxton, Meredith, Buzgau, Adrian, Castellucci, Lana A, Chekuri, Sweta, Chen, Jen-Ting, Cheng, Allen C, Chkhikvadze, Tamta, Coiffard, Benjamin, Contreras, Aira, Costantini, Todd W, de Brouwer, Sophie, Detry, Michelle A, Duggal, Abhijit, Džavík, Vladimír, Effron, Mark B, Eng, Heather F, Escobedo, Jorge, Estcourt, Lise J, Everett, Brendan M, Fergusson, Dean A, Fitzgerald, Mark, Fowler, Robert A, Froess, Joshua D, Fu, Zhuxuan, Galanaud, Jean P, Galen, Benjamin T, Gandotra, Sheetal, Girard, Timothy D, Goodman, Andrew L, Goossens, Herman, Green, Cameron, Greenstein, Yonatan Y, Gross, Peter L, Haniffa, Rashan, Hegde, Sheila M, Hendrickson, Carolyn M, Higgins, Alisa M, Hindenburg, Alexander A, Hope, Aluko A, Horowitz, James M, Horvat, Christopher M, Huang, David T, Hudock, Kristin, Hunt, Beverley J, Husain, Mansoor, Hyzy, Robert C, Jacobson, Jeffrey R, Jayakumar, Devachandran, Keller, Norma M, Khan, Akram, Kim, Yuri, Kindzelski, Andrei, King, Andrew J, Knudson, M Margaret, Kornblith, Aaron E, Kutcher, Matthew E, Laffan, Michael A, Lamontagne, Francois, Le Gal, Grégoire

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Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19 von Lawler, Patrick R, Goligher, Ewan C, Berger, Jeffrey S, Neal, Matthew D, McVerry, Bryan J, Nicolau, Jose C, Gong, Michelle N, Carrier, Marc, Rosenson, Robert S, Reynolds, Harmony R, Turgeon, Alexis F, Escobedo, Jorge, Huang, David T, Bradbury, Charlotte A, Houston, Brett L, Kornblith, Lucy Z, Kumar, Anand, Kahn, Susan R, Cushman, Mary, McQuilten, Zoe, Slutsky, Arthur S, Kim, Keri S, Gordon, Anthony C, Kirwan, Bridget-Anne, Brooks, Maria M, Higgins, Alisa M, Lewis, Roger J, Lorenzi, Elizabeth, Berry, Scott M, Berry, Lindsay R, Aday, Aaron W, Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M, Aryal, Diptesh, Baumann Kreuziger, Lisa, Beane, Abi, Bhimani, Zahra, Bihari, Shailesh, Billett, Henny H, Bond, Lindsay, Bonten, Marc, Brunkhorst, Frank, Buxton, Meredith, Buzgau, Adrian, Castellucci, Lana A, Chekuri, Sweta, Chen, Jen-Ting, Cheng, Allen C, Chkhikvadze, Tamta, Coiffard, Benjamin, Costantini, Todd W, de Brouwer, Sophie, Derde, Lennie P G, Detry, Michelle A, Duggal, Abhijit, Džavík, Vladimír, Effron, Mark B, Estcourt, Lise J, Everett, Brendan M, Fergusson, Dean A, Fitzgerald, Mark, Fowler, Robert A, Galanaud, Jean P, Galen, Benjamin T, Gandotra, Sheetal, García-Madrona, Sebastian, Girard, Timothy D, Godoy, Lucas C, Goodman, Andrew L, Goossens, Herman, Green, Cameron, Greenstein, Yonatan Y, Gross, Peter L, Hamburg, Naomi M, Haniffa, Rashan, Hanna, George, Hanna, Nicholas, Hegde, Sheila M, Hendrickson, Carolyn M, Hite, R Duncan, Hindenburg, Alexander A, Hope, Aluko A, Horowitz, James M, Horvat, Christopher M, Hudock, Kristin, Hunt, Beverley J, Husain, Mansoor, Hyzy, Robert C, Iyer, Vivek N, Jacobson, Jeffrey R, Jayakumar, Devachandran, Keller, Norma M, Khan, Akram, Kim, Yuri, Kindzelski, Andrei L, King, Andrew J, Knudson, M Margaret, Kornblith, Aaron E, Krishnan, Vidya

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Human colonic crypts in culture: segregation of immunochemical markers in normal versus adenoma-derived von Dame, Michael K, Jiang, Yan, Appelman, Henry D, Copley, Kelly D, McClintock, Shannon D, Aslam, Muhammad Nadeem, Attili, Durga, Elmunzer, B Joseph, Brenner, Dean E, Varani, James, Turgeon, D Kim

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The critical role of psychosine in screening, diagnosis, and monitoring of Krabbe disease von Guenzel, Adam J., Turgeon, Coleman T., Nickander, Kim K., White, Amy L., Peck, Dawn S., Pino, Gisele B., Studinski, April L., Prasad, Vinod K., Kurtzberg, Joanne, Escolar, Maria L., Lasio, Maria Laura Duque, Pellegrino, Joan E., Sakonju, Ai, Hickey, Rachel E., Shallow, Natalie M., Ream, Margie A., Orsini, Joseph J., Gelb, Michael H., Raymond, Kimiyo, Gavrilov, Dimitar K., Oglesbee, Devin, Rinaldo, Piero, Tortorelli, Silvia, Matern, Dietrich

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Calcium-Induced Differentiation of Human Colon Adenomas in Colonoid Culture: Calcium Alone versus Calcium with Additional Trace Elements von McClintock, Shannon D, Colacino, Justin A, Attili, Durga, Dame, Michael K, Richter, Aliah, Reddy, Anusha R, Basrur, Venkatesha, Rizvi, Areeba H, Turgeon, D Kim, Varani, James, Aslam, Muhammad N

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Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain von Verret, Michael, Lauzier, François, Zarychanski, Ryan, Perron, Caroline, Savard, Xavier, Pinard, Anne-Marie, Leblanc, Guillaume, Cossi, Marie-Joëlle, Neveu, Xavier, Turgeon, Alexis F

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Failure of anticoagulant thromboprophylaxis: risk factors in medical-surgical critically ill patients von Lim, Wendy, Meade, Maureen, Lauzier, Francois, Zarychanski, Ryan, Mehta, Sangeeta, Lamontagne, Francois, Dodek, Peter, McIntyre, Lauralyn, Hall, Richard, Heels-Ansdell, Diane, Fowler, Robert, Pai, Menaka, Guyatt, Gordon, Crowther, Mark A, Warkentin, Theodore E, Devereaux, P J, Walter, Stephen D, Muscedere, John, Herridge, Margaret, Turgeon, Alexis F, Geerts, William, Finfer, Simon, Jacka, Michael, Berwanger, Otavio, Ostermann, Marlies, Qushmaq, Ismael, Friedrich, Jan O, Cook, Deborah J

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Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support–Free Days in Patients Hospitalized With COVID-19: A Randomized Clinic... von Lawler, Patrick R, Derde, Lennie P. G, van de Veerdonk, Frank L, McVerry, Bryan J, Huang, David T, Berry, Lindsay R, Lorenzi, Elizabeth, van Kimmenade, Roland, Gommans, Frank, Vaduganathan, Muthiah, Leaf, David E, Baron, Rebecca M, Kim, Edy Y, Frankfurter, Claudia, Epelman¸, Slava, Kwan, Yvonne, Grieve, Richard, O'Neill, Stephen, Sadique, Zia, Puskarich, Michael, Marshall, John C, Higgins, Alisa M, Mouncey, Paul R, Rowan, Kathryn M, Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M, Au, Carly, Beane, Abi, van Bentum-Puijk, Wilma, Bonten, Marc J. M, Bradbury, Charlotte A, Brunkhorst, Frank M, Burrell, Aidan, Buzgau, Adrian, Buxton, Meredith, Cecconi, Maurizio, Cheng, Allen C, Cove, Matthew, Detry, Michelle A, Estcourt, Lise J, Ezekowitz, Justin, Fitzgerald, Mark, Gattas, David, Godoy, Lucas C, Goossens, Herman, Haniffa, Rashan, Harrison, David A, Hills, Thomas, Horvat, Christopher M, Ichihara, Nao, Lamontagne, Francois, Linstrum, Kelsey M, McAuley, Daniel F, McGlothlin, Anna, McGuinness, Shay P, McQuilten, Zoe, Murthy, Srinivas, Nichol, Alistair D, Owen, David R. J, Parke, Rachael L, Parker, Jane C, Pollock, Katrina M, Reyes, Luis Felipe, Saito, Hiroki, Santos, Marlene S, Saunders, Christina T, Seymour, Christopher W, Shankar-Hari, Manu, Singh, Vanessa, Turgeon, Alexis F, Turner, Anne M, Zarychanski, Ryan, Green, Cameron, Lewis, Roger J, Angus, Derek C, Berry, Scott, Gordon, Anthony C, McArthur, Colin J, Webb, Steve A

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Optimal Timing of Administration of Direct-acting Antivirals for Patients With Hepatitis C-associated Hepatocellular Carcinoma Undergoing Liver Transplantation von Turgeon, Michael K., Shah, Shimul A., Delman, Aaron M., Tran, Benjamin V., Agopian, Vatche G., Wedd, Joel P., Magliocca, Joseph F., Kim, Ahyoung, Cameron, Andrew, Olyaei, Ali, Orloff, Susan L., Anderson, Matthew P., Kubal, Chandrashekhar A., Cannon, Robert M., Locke, Jayme E., Simpson, Mary A., Akoad, Mohamed E., Wongjirad, Chelsey P., Emamaullee, Juliet, Moro, Amika, Aucejo, Federico, Feizpour, Cyrus A., Vagefi, Parsia A., Nguyen, Mindie H., Esquivel, Carlos O., Dhanireddy, Kiran, Subramanian, Vijay, Chavarriaga, Alejandro, Kazimi, Marwan M., Anderson, Maia S., Sonnenday, Christopher J., Kim, Steven C., Foley, David P., Abdouljoud, Marwan, Salgia, Reena J., Moris, Dimitrios, Sudan, Debra L., Ganesh, Swaytha R., Humar, Abhinav, Doyle, Majella, Chapman, William C., Maithel, Shishir K.

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Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial von Arabi, Yaseen M., Gordon, Anthony C., Derde, Lennie P. G., Nichol, Alistair D., Murthy, Srinivas, Beidh, Farah Al, Annane, Djillali, Swaidan, Lolowa Al, Beane, Abi, Beasley, Richard, Berry, Lindsay R., Bhimani, Zahra, Bonten, Marc J. M., Bradbury, Charlotte A., Brunkhorst, Frank M., Buxton, Meredith, Buzgau, Adrian, Cheng, Allen, De Jong, Menno, Detry, Michelle A., Duffy, Eamon J., Estcourt, Lise J., Fitzgerald, Mark, Fowler, Rob, Girard, Timothy D., Goligher, Ewan C., Goossens, Herman, Haniffa, Rashan, Higgins, Alisa M., Hills, Thomas E., Horvat, Christopher M., Huang, David T., King, Andrew J., Lamontagne, Francois, Lawler, Patrick R., Lewis, Roger, Linstrum, Kelsey, Litton, Edward, Lorenzi, Elizabeth, Malakouti, Salim, McAuley, Daniel F., McGlothlin, Anna, Mcguinness, Shay, McVerry, Bryan J., Montgomery, Stephanie K., Morpeth, Susan C., Mouncey, Paul R., Orr, Katrina, Parke, Rachael, Parker, Jane C., Patanwala, Asad E., Rowan, Kathryn M., Santos, Marlene S., Saunders, Christina T., Seymour, Christopher W., Shankar-Hari, Manu, Tong, Steven Y. C., Turgeon, Alexis F., Turner, Anne M., Van de Veerdonk, Frank Leo, Zarychanski, Ryan, Green, Cameron, Berry, Scott, Marshall, John C., McArthur, Colin, Angus, Derek C., Webb, Steven A.

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Exploring the experiences and perspectives of substitute decision-makers involved in decisions about deceased organ donation: a qualitative study protocol von Crawshaw, Jacob, Presseau, Justin, van Allen, Zack, Pinheiro Carvalho, Livia, Jordison, Kim, English, Shane, Fergusson, Dean A, Lauzier, Francois, Turgeon, Alexis F, Sarti, Aimee J, Martin, Claudio, D'Aragon, Frédérick, Li, Alvin Ho-ting, Knoll, Greg, Ball, Ian, Brehaut, Jamie, Burns, Karen E A, Fortin, Marie-Chantal, Weiss, Matthew, Meade, Maureen, Marsolais, Pierre, Shemie, Sam, Zaabat, Sanabelle, Dhanani, Sonny, Kitto, Simon C, Chassé, Michaël

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Mapping the adult human esophagus in vivo and in vitro von Ferrer-Torres, Daysha, Wu, Joshua H, Zhang, Charles J, Hammer, Max A, Dame, Michael K, Wu, Angeline, Holloway, Emily M, Karpoff, Kateryna, McCarthy, Caroline L, Bohm, Margaret S, Cuttitta, Ashley J, Tigani, Dominic J, Huang, Sha, Tsai, Yu-Hwai, Miller, Alyssa J, Walker, Taylor, Bayer, David E, Hogan, Simon P, Turgeon, Danielle Kim, Lin, Jules, Higgins, Peter D R, Sexton, Jonathan, Spence, Jason R

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How do natural changes in flow magnitude affect fish abundance and diversity in temperate regions? A systematic review protocol von Birnie‐Gauvin, Kim, Rytwinski, Trina, Harper, Meagan, Taylor, Jessica J., Smith, Adrienne, Smokorowski, Karen E., Turgeon, Katrine, Bradford, Michael J., Cooke, Steven J.

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Frequency of Screening and Spontaneous Breathing Trial Techniques: A Randomized Clinical Trial von Burns, Karen E. A, Wong, Jessica, Rizvi, Leena, Lafreniere-Roula, Myriam, Thorpe, Kevin, Devlin, John W, Cook, Deborah J, Seely, Andrew, Dodek, Peter M, Tanios, Maged, Piraino, Thomas, Gouskos, Audrey, Kiedrowski, Kenneth C, Kay, Phyllis, Mitchell, Susan, Merner, George W, Mayette, Michael, D’Aragon, Frederick, Lamontagne, Francois, Rochwerg, Bram, Turgeon, Alexis, Sia, Ying Tung, Charbonney, Emmanuel, Aslanian, Pierre, Criner, Gerard J, Hyzy, Robert C, Beitler, Jeremy R, Kassis, Elias Baedorf, Kutsogiannis, Demetrios James, Meade, Maureen O, Liebler, Janice, Iyer-Kumar, Santhi, Tsang, Jennifer, Cirone, Robert, Shanholtz, Carl, Hill, Nicholas S

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