DNA repair targeted therapy: The past or future of cancer treatment? von Gavande, Navnath S, VanderVere-Carozza, Pamela S, Hinshaw, Hilary D, Jalal, Shadia I, Sears, Catherine R, Pawelczak, Katherine S, Turchi, John J

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Modulating DNA Repair Pathways to Improve Precision Genome Engineering von Pawelczak, Katherine S, Gavande, Navnath S, VanderVere-Carozza, Pamela S, Turchi, John J

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A special issue on DNA damage responses and genome maintenance von Li, Guo-Min, Chen, David J, Mitra, Sankar, Turchi, John J

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Eukaryotic nucleotide excision repair： from understanding mechanisms to influencing biology von Shuck, Sarah C, Short, Emily A, Turchi, John J

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The effect of replication protein A inhibition and post-translational modification on ATR kinase signaling von Jordan, Matthew R., Oakley, Greg G., Mayo, Lindsey D., Balakrishnan, Lata, Turchi, John J.

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DNA Repair: From Genome Maintenance to Biomarker and Therapeutic Target von JALAL, Shadia, EARLEY, Jennifer N, TURCHI, John J

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Discovery and development of novel DNA-PK inhibitors by targeting the unique Ku–DNA interaction von Gavande, Navnath S, VanderVere-Carozza, Pamela S, Pawelczak, Katherine S, Mendoza-Munoz, Pamela, Vernon, Tyler L, Hanakahi, Leslyn A, Summerlin, Matthew, Dynlacht, Joseph R, Farmer, Annabelle H, Sears, Catherine R, Nasrallah, Nawar Al, Garrett, Joy, Turchi, John J

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Complex Cisplatin-Double Strand Break (DSB) Lesions Directly Impair Cellular Non-Homologous End-Joining (NHEJ) Independent of Downstream Damage Response (DDR) Pathways von Sears, Catherine R., Turchi, John J.

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The novel, small-molecule DNA methylation inhibitor SGI-110 as an ovarian cancer chemosensitizer von Fang, Fang, Munck, Joanne, Tang, Jessica, Taverna, Pietro, Wang, Yinu, Miller, David F B, Pilrose, Jay, Choy, Gavin, Azab, Mohammad, Pawelczak, Katherine S, VanderVere-Carozza, Pamela, Wagner, Michael, Lyons, John, Matei, Daniela, Turchi, John J, Nephew, Kenneth P

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Chemotherapy induced DNA damage response: Convergence of drugs and pathways von Woods, Derek, Turchi, John J.

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The mechanistic role of cardiac glycosides in DNA damage response and repair signaling von Ainembabazi, Diana, Zhang, Youwei, Turchi, John J.

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Editorial: Targeting DNA repair and the DNA damage response: Beyond the standard PI3 kinase-like kinases von Turchi, John J, Pawelczak, Katherine S, Weinfeld, Michael, McHugh, Peter J

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Extracellular Tissue Transglutaminase Activates Noncanonical NF-κB Signaling and Promotes Metastasis in Ovarian Cancer von Yakubov, Bakhtiyor, Chelladurai, Bhadrani, Schmitt, Jordan, Emerson, Robert, Turchi, John J, Matei, Daniela

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Recent Advances in the Development of Non-PIKKs Targeting Small Molecule Inhibitors of DNA Double-Strand Break Repair von Kelm, Jeremy M, Samarbakhsh, Amirreza, Pillai, Athira, VanderVere-Carozza, Pamela S, Aruri, Hariprasad, Pandey, Deepti S, Pawelczak, Katherine S, Turchi, John J, Gavande, Navnath S

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Recognition of DNA Termini by the C-Terminal Region of the Ku80 and the DNA-Dependent Protein Kinase Catalytic Subunit von Woods, Derek S, Sears, Catherine R, Turchi, John J

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In Vivo Targeting Replication Protein A for Cancer Therapy von VanderVere-Carozza, Pamela S, Gavande, Navnath S, Jalal, Shadia I, Pollok, Karen E, Ekinci, Elmira, Heyza, Joshua, Patrick, Steve M, Masters, Andi, Turchi, John J, Pawelczak, Katherine S

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Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency von Cong, Ke, Peng, Min, Kousholt, Arne Nedergaard, Lee, Wei Ting C., Lee, Silviana, Nayak, Sumeet, Krais, John, VanderVere-Carozza, Pamela S., Pawelczak, Katherine S., Calvo, Jennifer, Panzarino, Nicholas J., Turchi, John J., Johnson, Neil, Jonkers, Jos, Rothenberg, Eli, Cantor, Sharon B.

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Characterization and initial demonstration of in vivo efficacy of a novel heat-activated metalloenediyne anti-cancer agent von Garrett, Joy, Metzger, Erin, Dewhirst, Mark W., Pollok, Karen E., Turchi, John J., Le Poole, Isabelle C., Couch, Kira, Lew, Logan, Sinn, Anthony, Zaleski, Jeffrey M., Dynlacht, Joseph R.

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Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency von Cong, Ke, Peng, Min, Kousholt, Arne Nedergaard, Lee, Wei Ting C, Lee, Silviana, Nayak, Sumeet, Krais, John, VanderVere-Carozza, Pamela S, Pawelczak, Katherine S, Calvo, Jennifer, Panzarino, Nicholas J, Turchi, John J, Johnson, Neil, Jonkers, Jos, Rothenberg, Eli, Cantor, Sharon B

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Ku–DNA binding inhibitors modulate the DNA damage response in response to DNA double-strand breaks von Mendoza-Munoz, Pamela L, Gavande, Navnath S, VanderVere-Carozza, Pamela S, Pawelczak, Katherine S, Dynlacht, Joseph R, Garrett, Joy E, Turchi, John J

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