The Hsp90 inhibitor IPI-504 rapidly lowers EML4-ALK levels and induces tumor regression in ALK-driven NSCLC models von Normant, E, Paez, G, West, K A, Lim, A R, Slocum, K L, Tunkey, C, McDougall, J, Wylie, A A, Robison, K, Caliri, K, Palombella, V J, Fritz, C C

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Quantitative analysis of gene regulation by seven clinically relevant progestins suggests a highly similar mechanism of action through progesterone receptors in T47D breast cancer... von Bray, Jeffrey D., Jelinsky, Scott, Ghatge, Radhika, Bray, Jenifer A., Tunkey, Christopher, Saraf, Kathryn, Jacobsen, Britta M., Richer, Jennifer K., Brown, Eugene L., Winneker, Richard C., Horwitz, Kathryn B., Lyttle, C. Richard

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210 EML4-ALK is a sensitive client protein of Hsp90, and rearrangements of the ALK locus are associated with clinical response to IPI-504 (retaspimycin hydrochloride), a novel Hsp9... von Fritz, C, Lim, A, Slocum, K, Tunkey, C, Paez, G, West, K, Ross, R, Normant, E, Sequist, L, Palombella, V

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Global transcription profiling of estrogen activity: Estrogen receptor a regulates gene expression in the kidney von JELINSKY, Scott A, HARRIS, Heather A, BROWN, Eugene L, FLANAGAN, Kathryn, XIAOCHUN ZHANG, TUNKEY, Christopher, LAI, Kehdih, LANE, Malcolm V, SIMCOE, Donna K, EVANS, Mark J

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Safety and activity of IPI-504 (retaspimycin hydrochloride) and docetaxel in pretreated patients (pts) with metastatic non-small cell lung cancer (NSCLC) von Riely, G. J., Gettinger, S. N., Stoller, R. G., Gabrail, N. Y., Dy, G. K., Weiss, G. J., Tunkey, C., Skliris, G., Strychor, S., Dunbar, J., DeLucia, D., Ross, R. W., Gray, J. E.

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Exploiting genotypic differences to identify genes important for EAE development von Jelinsky, Scott A., Miyashiro, Joy S., Saraf, Kathryn A., Tunkey, Christopher, Reddy, Padma, Newcombe, Jia, Oestreicher, Judith L., Brown, Eugene, Trepicchio, William L., Leonard, John P., Marusic, Suzana

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A comprehensive assay for CFTR mutational analysis using next-generation sequencing von Abou Tayoun, Ahmad N, Tunkey, Christopher D, Pugh, Trevor J, Ross, Tristen, Shah, Minita, Lee, Clarence C, Harkins, Timothy T, Wells, Wendy A, Tafe, Laura J, Amos, Christopher I, Tsongalis, Gregory J

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Hedgehog pathway inhibitor saridegib (IPI-926) increases lifespan in a mouse medulloblastoma model von Lee, Michelle J, Hatton, Beryl A, Villavicencio, Elisabeth H, Khanna, Paritosh C, Friedman, Seth D, Ditzler, Sally, Pullar, Barbara, Robison, Keith, White, Kerry F, Tunkey, Chris, LeBlanc, Michael, Randolph-Habecker, Julie, Knoblaugh, Sue E, Hansen, Stacey, Richards, Andrew, Wainwright, Brandon J, McGovern, Karen, Olson, James M

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Transcriptional changes associated with breast cancer occur as normal human mammary epithelial cells overcome senescence barriers and become immortalized von Li, Yizheng, Pan, Jing, Li, Jian-Liang, Lee, Jee Hyung, Tunkey, Chris, Saraf, Katie, Garbe, James C, Whitley, Maryann Z, Jelinsky, Scott A, Stampfer, Martha R, Haney, Steven A

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A Comprehensive Assay for CFTR Mutational Analysis Using Next‐Generation Sequencing von Abou Tayoun, Ahmad N., Tunkey, Christopher D., Tafe, Laura J., Levandowsky, Elizabeth, Spangler, Jessica, Dindinger, Matthew, Ross, Tristen, Shah, Minita, McLaughlin, Stephen, Lee, Clarence C., Harkins, Timothy T., Raia, Gabrielle, Amos, Christopher I., Wells, Wendy A., Tsongalis, Gregory J.

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