Comparison of inhibitory effects of irreversible and reversible Btk inhibitors on platelet function von Tullemans, Bibian M.E., Karel, Mieke F.A., Léopold, Valentine, ten Brink, Marieke S., Baaten, Constance C.F.M.J., Maas, Sanne L., Vos, Alex F., Eble, Johannes A., Nijziel, Marten R., Vorst, Emiel P.C., Cosemans, Judith M.E.M., Heemskerk, Johan W.M., Claushuis, Theodora A.M., Kuijpers, Marijke J.E.

Volltext

Native, Intact Glucagon-Like Peptide 1 Is a Natural Suppressor of Thrombus Growth Under Physiological Flow Conditions von Sternkopf, Marieke, Nagy, Magdolna, Baaten, Constance C.F.M.J., Kuijpers, Marijke J.E., Tullemans, Bibian M.E., Wirth, Julia, Theelen, Wendy, Mastenbroek, Tom G., Lehrke, Michael, Winnerling, Benjamin, Baerts, Lesley, Marx, Nikolaus, De Meester, Ingrid, Döring, Yvonne, Cosemans, Judith M.E.M., Daiber, Andreas, Steven, Sebastian, Jankowski, Joachim, Heemskerk, Johan W.M., Noels, Heidi

Volltext

Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia von Marsch, Elke, Demandt, Jasper A F, Theelen, Thomas L, Tullemans, Bibian M E, Wouters, Kristiaan, Boon, Mariëtte R, van Dijk, Theo H, Gijbels, Marion J, Dubois, Ludwig J, Meex, Steven J R, Mazzone, Massimiliano, Hung, Gene, Fisher, Edward A, Biessen, Erik A L, Daemen, Mat J A P, Rensen, Patrick C N, Carmeliet, Peter, Groen, Albert K, Sluimer, Judith C

Volltext

Ultra-high-throughput Ca2+ assay in platelets to distinguish ITAM-linked and G-protein-coupled receptor activation von Fernández, Delia I., Provenzale, Isabella, Cheung, Hilaire Y.F., van Groningen, Jan, Tullemans, Bibian M.E., Veninga, Alicia, Dunster, Joanne L., Honarnejad, Saman, van den Hurk, Helma, Kuijpers, Marijke J.E., Heemskerk, Johan W.M.

Volltext

Ultra-high throughput-based screening for the discovery of antiplatelet drugs affecting receptor dependent calcium signaling dynamics von Fernández, Delia I., Troitiño, Sara, Sobota, Vladimír, Tullemans, Bibian M. E., Zou, Jinmi, van den Hurk, Helma, García, Ángel, Honarnejad, Saman, Kuijpers, Marijke J. E., Heemskerk, Johan W. M.

Volltext

Galectin-1 and platelet factor 4 (CXCL4) induce complementary platelet responses in vitro von Dickhout, Annemiek, Tullemans, Bibian M. E., Heemskerk, Johan W. M., Thijssen, Victor L. J. L., Kuijpers, Marijke J. E., Koenen, Rory R.

Volltext

Multiparameter Evaluation of the Platelet-Inhibitory Effects of Tyrosine Kinase Inhibitors Used for Cancer Treatment von Tullemans, Bibian M. E., Veninga, Alicia, Fernandez, Delia, Aarts, Maureen J. B., Eble, Johannes A., van der Meijden, Paola E. J., Heemskerk, Johan W. M., Kuijpers, Marijke J. E.

Volltext

Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear von Hrdinova, Johana, Fernández, Delia I, Ercig, Bogac, Tullemans, Bibian M E, Suylen, Dennis P L, Agten, Stijn M, Jurk, Kerstin, Hackeng, Tilman M, Vanhoorelbeke, Karen, Voorberg, Jan, Reutelingsperger, Chris P M, Wichapong, Kanin, Heemskerk, Johan W M, Nicolaes, Gerry A F

Volltext

Mild hyperlipidemia in mice aggravates platelet responsiveness in thrombus formation and exploration of platelet proteome and lipidome von van Geffen, Johanna P., Swieringa, Frauke, van Kuijk, Kim, Tullemans, Bibian M. E., Solari, Fiorella A., Peng, Bing, Clemetson, Kenneth J., Farndale, Richard W., Dubois, Ludwig J., Sickmann, Albert, Zahedi, René P., Ahrends, Robert, Biessen, Erik A. L., Sluimer, Judith C., Heemskerk, Johan W. M., Kuijpers, Marijke J. E.

Volltext

Maintenance of murine platelet homeostasis by the kinase Csk and phosphatase CD148 von Mori, Jun, Nagy, Zoltan, Di Nunzio, Giada, Smith, Christopher W., Geer, Mitchell J., Al Ghaithi, Rashid, van Geffen, Johanna P., Heising, Silke, Boothman, Luke, Tullemans, Bibian M.E., Correia, Joao N., Tee, Louise, Kuijpers, Marijke J.E., Harrison, Paul, Heemskerk, Johan W.M., Jarvis, Gavin E., Tarakhovsky, Alexander, Weiss, Arthur, Mazharian, Alexandra, Senis, Yotis A.

Volltext

Design, manufacturing and testing of a green non-isocyanate polyurethane prosthetic heart valve von Melo, Sofia F, Nondonfaz, Alicia, Aqil, Abdelhafid, Pierrard, Anna, Hulin, Alexia, Delierneux, Céline, Ditkowski, Bartosz, Gustin, Maxime, Legrand, Maxime, Tullemans, Bibian M. E, Brouns, Sanne L. N, Nchimi, Alain, Carrus, Raoul, Dejosé, Astrid, Heemskerk, Johan W. M, Kuijpers, Marijke J. E, Ritter, Jan, Steinseifer, Ulrich, Clauser, Johanna C, Jérôme, Christine, Lancellotti, Patrizio, Oury, Cécile

Volltext

Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis von Geer, Mitchell J., van Geffen, Johanna P., Gopalasingam, Piraveen, Vögtle, Timo, Smith, Christopher W., Heising, Silke, Kuijpers, Marijke J.E., Tullemans, Bibian M.E., Jarvis, Gavin E., Eble, Johannes A., Jeeves, Mark, Overduin, Michael, Heemskerk, Johan W.M., Mazharian, Alexandra, Senis, Yotis A.

Volltext

Quantitative and qualitative changes in platelet traits of sunitinib-treated patients with renal cell carcinoma in relation to circulating sunitinib levels: a proof-of-concept stud... von Tullemans, Bibian M E, Brouns, Sanne L N, Swieringa, Frauke, Sabrkhany, Siamack, van den Berkmortel, Franchette W P J, Peters, Natascha A J B, de Bruijn, Peter, Koolen, Stijn L W, Heemskerk, Johan W M, Aarts, Maureen J B, Kuijpers, Marijke J E

Volltext

GPVI expression is linked to platelet size, age, and reactivity von Veninga, Alicia, Handtke, Stefan, Aurich, Konstanze, Tullemans, Bibian M.E., Brouns, Sanne L.N., Schwarz, Silas L., Heubel-Moenen, Floor C.J.I., Greinacher, Andreas, Heemskerk, Johan W.M., van der Meijden, Paola E.J., Thiele, Thomas

Volltext

Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear von Hrdinova, Johana, Fernandez, Delia I, Ercig, Bogac, Tullemans, Bibian M.E, Suylen, Dennis P.L, Agten, Stijn M, Jurk, Kerstin, Hackeng, Tilman M, Vanhoorelbeke, Karen, Voorberg, Jan, Reutelingsperger, Chris P.M, Wichapong, Kanin, Heemskerk, Johan W.M, Nicolaes, Gerry A.F

Volltext

Protein C or Protein S deficiency associates with paradoxically impaired platelet‐dependent thrombus and fibrin formation under flow von Brouns, Sanne L.N., Tullemans, Bibian M.E., Bulato, Cristiana, Perrella, Gina, Campello, Elena, Spiezia, Luca, van Geffen, Johanna P., Kuijpers, Marijke J.E., van Oerle, René, Spronk, Henri M.H., van der Meijden, Paola E.J., Simioni, Paolo, Heemskerk, Johan W.M.

Volltext

Tyrosine Kinase Inhibitor Pazopanib Inhibits Platelet Procoagulant Activity in Renal Cell Carcinoma Patients von Tullemans, Bibian M E, Nagy, Magdolna, Sabrkhany, Siamack, Griffioen, Arjan W, Oude Egbrink, Mirjam G A, Aarts, Maureen, Heemskerk, Johan W M, Kuijpers, Marijke J E

Volltext

Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia von Marsch, Elke, Demandt, Jasper A.F, Theelen, Thomas L, Tullemans, Bibian M.E, Wouters, Kristiaan, Boon, Mariëtte R, van Dijk, Theo H, Gijbels, Marion J, Dubois, Ludwig J, Meex, Steven J.R, Mazzone, Max, Hung, Gene, Fisher, Edward A, Biessen, Erik A.L, Daemen, Mat J.A.P, Rensen, Patrick C.N, Carmeliet, Peter, Groen, Albert K, Sluimer, Judith C

Volltext