A Recently Evolved Transcriptional Network Controls Biofilm Development in Candida albicans von Nobile, Clarissa J., Fox, Emily P., Nett, Jeniel E., Sorrells, Trevor R., Mitrovich, Quinn M., Hernday, Aaron D., Tuch, Brian B., Andes, David R., Johnson, Alexander D.

Volltext

Deterministic and stochastic allele specific gene expression in single mouse blastomeres von Tang, Fuchou, Barbacioru, Catalin, Nordman, Ellen, Bao, Siqin, Lee, Caroline, Wang, Xiaohui, Tuch, Brian B, Heard, Edith, Lao, Kaiqin, Surani, M Azim

Volltext

Selective RET kinase inhibition for patients with RET-altered cancers von Subbiah, V., Velcheti, V., Tuch, B.B., Ebata, K., Busaidy, N.L., Cabanillas, M.E., Wirth, L.J., Stock, S., Smith, S., Lauriault, V., Corsi-Travali, S., Henry, D., Burkard, M., Hamor, R., Bouhana, K., Winski, S., Wallace, R.D., Hartley, D., Rhodes, S., Reddy, M., Brandhuber, B.J., Andrews, S., Rothenberg, S.M., Drilon, A.

Volltext

mRNA-Seq whole-transcriptome analysis of a single cell von Tuch, Brian B, Bodeau, John, Siddiqui, Asim, Nordman, Ellen, Tang, Fuchou, Wang, Xiaohui, Xu, Nanlan, Surani, M Azim, Wang, Yangzhou, Barbacioru, Catalin, Lee, Clarence, Lao, Kaiqin

Volltext

RET Solvent Front Mutations Mediate Acquired Resistance to Selective RET Inhibition in RET-Driven Malignancies von Solomon, Benjamin J., Tan, Lavinia, Lin, Jessica J., Wong, Stephen Q., Hollizeck, Sebastian, Ebata, Kevin, Tuch, Brian B., Yoda, Satoshi, Gainor, Justin F., Sequist, Lecia V., Oxnard, Geoffrey R., Gautschi, Oliver, Drilon, Alexander, Subbiah, Vivek, Khoo, Christine, Zhu, Edward Y., Nguyen, Michele, Henry, Dahlia, Condroski, Kevin R., Kolakowski, Gabrielle R., Gomez, Eliana, Ballard, Joshua, Metcalf, Andrew T., Blake, James F., Dawson, Sarah-Jane, Blosser, Wayne, Stancato, Louis F., Brandhuber, Barbara J., Andrews, Steve, Robinson, Bruce G., Rothenberg, S. Michael

Volltext

Resistance to TRK inhibition mediated by convergent MAPK pathway activation von Cocco, Emiliano, Schram, Alison M., Kulick, Amanda, Misale, Sandra, Won, Helen H., Yaeger, Rona, Razavi, Pedram, Ptashkin, Ryan, Hechtman, Jaclyn F., Toska, Eneda, Cownie, James, Somwar, Romel, Shifman, Sophie, Mattar, Marissa, Selçuklu, S. Duygu, Samoila, Aliaksandra, Guzman, Sean, Tuch, Brian B., Ebata, Kevin, de Stanchina, Elisa, Nagy, Rebecca J., Lanman, Richard B., Houck-Loomis, Brian, Patel, Juber A., Berger, Michael F., Ladanyi, Marc, Hyman, David M., Drilon, Alexander, Scaltriti, Maurizio

Volltext

Larotrectinib in adult patients with solid tumours: a multi-centre, open-label, phase I dose-escalation study von Hong, D.S., Bauer, T.M., Lee, J.J., Dowlati, A., Brose, M.S., Farago, A.F., Taylor, M., Shaw, A.T., Montez, S., Meric-Bernstam, F., Smith, S., Tuch, B.B., Ebata, K., Cruickshank, S., Cox, M.C., Burris, H.A., Doebele, R.C.

Volltext

An iron homeostasis regulatory circuit with reciprocal roles in Candida albicans commensalism and pathogenesis von Chen, Changbin, Pande, Kalyan, French, Sarah D, Tuch, Brian B, Noble, Suzanne M

Volltext

TNF-related apoptosis-inducing ligand (TRAIL) protects against diabetes and atherosclerosis in Apoe−/− mice von Di Bartolo, B. A., Chan, J., Bennett, M. R., Cartland, S., Bao, S., Tuch, B. E., Kavurma, M. M.

Volltext

Intersecting transcription networks constrain gene regulatory evolution von Sorrells, Trevor R., Booth, Lauren N., Tuch, Brian B., Johnson, Alexander D.

Volltext

Interlocking transcriptional feedback loops control white-opaque switching in Candida albicans von Zordan, Rebecca E, Miller, Mathew G, Galgoczy, David J, Tuch, Brian B, Johnson, Alexander D

Volltext

The evolution of combinatorial gene regulation in fungi von Tuch, Brian B, Galgoczy, David J, Hernday, Aaron D, Li, Hao, Johnson, Alexander D

Volltext

Evolution of Eukaryotic Transcription Circuits von Tuch, Brian B, Li, Hao, Johnson, Alexander D

Volltext

The transcriptomes of two heritable cell types illuminate the circuit governing their differentiation von Tuch, Brian B, Mitrovich, Quinn M, Homann, Oliver R, Hernday, Aaron D, Monighetti, Cinna K, De La Vega, Francisco M, Johnson, Alexander D

Volltext

Zetomipzomib (KZR-616) attenuates lupus in mice via modulation of innate and adaptive immune responses von Muchamuel, Tony, Fan, R Andrea, Anderl, Janet L, Bomba, Darrin J, Johnson, Henry W B, Lowe, Eric, Tuch, Brian B, McMinn, Dustin L, Millare, Beatriz, Kirk, Christopher J

Volltext

Extensive DNA-binding specificity divergence of a conserved transcription regulator von Baker, Christopher R., Tuch, Brian B., Johnson, Alexander D., Ptashne, Mark

Volltext

Glucagon-like peptide-1 enhances production of insulin in insulin-producing cells derived from mouse embryonic stem cells von Bai, L, Meredith, G, Tuch, B E

Volltext

Beneficial Effects of Desferrioxamine on Encapsulated Human Islets—In Vitro and In Vivo Study von Vaithilingam, V., Oberholzer, J., Guillemin, G. J., Tuch, B. E.

Volltext

Larotrectinib for paediatric solid tumours harbouring NTRK gene fusions: phase 1 results from a multicentre, open-label, phase 1/2 study von Laetsch, Theodore W, DuBois, Steven G, Mascarenhas, Leo, Turpin, Brian, Federman, Noah, Albert, Catherine M, Nagasubramanian, Ramamoorthy, Davis, Jessica L, Rudzinski, Erin, Feraco, Angela M, Tuch, Brian B, Ebata, Kevin T, Reynolds, Mark, Smith, Steven, Cruickshank, Scott, Cox, Michael C, Pappo, Alberto S, Hawkins, Douglas S

Volltext

Tumor transcriptome sequencing reveals allelic expression imbalances associated with copy number alterations von Tuch, Brian B, Laborde, Rebecca R, Xu, Xing, Gu, Jian, Chung, Christina B, Monighetti, Cinna K, Stanley, Sarah J, Olsen, Kerry D, Kasperbauer, Jan L, Moore, Eric J, Broomer, Adam J, Tan, Ruoying, Brzoska, Pius M, Muller, Matthew W, Siddiqui, Asim S, Asmann, Yan W, Sun, Yongming, Kuersten, Scott, Barker, Melissa A, De La Vega, Francisco M, Smith, David I

Volltext