Noise Can Induce Bimodality in Positive Transcriptional Feedback Loops Without Bistability von To, Tsz-Leung, Maheshri, Narendra

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Genetic Screen for Cell Fitness in High or Low Oxygen Highlights Mitochondrial and Lipid Metabolism von Jain, Isha H., Calvo, Sarah E., Markhard, Andrew L., Skinner, Owen S., To, Tsz-Leung, Ast, Tslil, Mootha, Vamsi K.

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Structure‐guided design of a reversible fluorogenic reporter of protein‐protein interactions von To, Tsz‐Leung, Zhang, Qiang, Shu, Xiaokun

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An engineered enzyme that targets circulating lactate to alleviate intracellular NADH:NAD+ imbalance von Patgiri, Anupam, Skinner, Owen S., Miyazaki, Yusuke, Schleifer, Grigorij, Marutani, Eizo, Shah, Hardik, Sharma, Rohit, Goodman, Russell P., To, Tsz-Leung, Robert Bao, Xiaoyan, Ichinose, Fumito, Zapol, Warren M., Mootha, Vamsi K.

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Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS von Shi, Xiaojian, Reinstadler, Bryn, Shah, Hardik, To, Tsz-Leung, Byrne, Katie, Summer, Luanna, Calvo, Sarah E., Goldberger, Olga, Doench, John G., Mootha, Vamsi K., Shen, Hongying

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A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering von To, Tsz-Leung, Cuadros, Alejandro M., Shah, Hardik, Hung, Wendy H.W., Li, Yang, Kim, Sharon H., Rubin, Daniel H.F., Boe, Ryan H., Rath, Sneha, Eaton, John K., Piccioni, Federica, Goodale, Amy, Kalani, Zohra, Doench, John G., Root, David E., Schreiber, Stuart L., Vafai, Scott B., Mootha, Vamsi K.

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Congenital Hypermetabolism and Uncoupled Oxidative Phosphorylation von Ganetzky, Rebecca D., Markhard, Andrew L., Yee, Irene, Clever, Sheila, Cahill, Alan, Shah, Hardik, Grabarek, Zenon, To, Tsz-Leung, Mootha, Vamsi K.

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Precision Optogenetic Tool for Selective Single- and Multiple-Cell Ablation in a Live Animal Model System von Makhijani, Kalpana, To, Tsz-Leung, Ruiz-González, Rubén, Lafaye, Céline, Royant, Antoine, Shu, Xiaokun

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Rationally designed fluorogenic protease reporter visualizes spatiotemporal dynamics of apoptosis in vivo von To, Tsz-Leung, Piggott, Beverly J., Makhijani, Kalpana, Yu, Dan, Jan, Yuh Nung, Shu, Xiaokun

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Spying on SARS-CoV-2 with Fluorescent Tags and Protease Reporters von To, Tsz-Leung, Li, Xiaoquan, Shu, Xiaokun

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Hypoxia extends lifespan and neurological function in a mouse model of aging von Rogers, Robert S, Wang, Hong, Durham, Timothy J, Stefely, Jonathan A, Owiti, Norah A, Markhard, Andrew L, Sandler, Lev, To, Tsz-Leung, Mootha, Vamsi K

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Rational Design of a GFP-Based Fluorogenic Caspase Reporter for Imaging Apoptosis In Vivo von To, Tsz-Leung, Schepis, Antonino, Ruiz-González, Rubén, Zhang, Qiang, Yu, Dan, Dong, Zhiqiang, Coughlin, Shaun R., Shu, Xiaokun

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Photoactivatable protein labeling by singlet oxygen mediated reactions von To, Tsz-Leung, Medzihradszky, Katalin F., Burlingame, Alma L., DeGrado, William F., Jo, Hyunil, Shu, Xiaokun

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Self-Assembly of VPS41 Promotes Sorting Required for Biogenesis of the Regulated Secretory Pathway von Asensio, Cédric S., Sirkis, Daniel W., Maas, James W., Egami, Kiyoshi, To, Tsz-Leung, Brodsky, Frances M., Shu, Xiaokun, Cheng, Yifan, Edwards, Robert H.

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MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations von Rath, Sneha, Sharma, Rohit, Gupta, Rahul, Ast, Tslil, Chan, Connie, Durham, Timothy J, Goodman, Russell P, Grabarek, Zenon, Haas, Mary E, Hung, Wendy H W, Joshi, Pallavi R, Jourdain, Alexis A, Kim, Sharon H, Kotrys, Anna V, Lam, Stephanie S, McCoy, Jason G, Meisel, Joshua D, Miranda, Maria, Panda, Apekshya, Patgiri, Anupam, Rogers, Robert, Sadre, Shayan, Shah, Hardik, Skinner, Owen S, To, Tsz-Leung, Walker, Melissa A, Wang, Hong, Ward, Patrick S, Wengrod, Jordan, Yuan, Chen-Ching, Calvo, Sarah E, Mootha, Vamsi K

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A genetically encoded system for oxygen generation in living cells von Markhard, Andrew L., McCoy, Jason G., To, Tsz-Leung, Mootha, Vamsi K.

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Detecting Activity at Different Length Scales: From Subdiffraction to Whole-Animal Activity von To, Tsz-Leung, Shu, Xiaokun

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Singlet oxygen triplet energy transfer-based imaging technology for mapping protein–protein proximity in intact cells von To, Tsz-Leung, Fadul, Michael J., Shu, Xiaokun

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A Molecular Model for Intercellular Synchronization in the Mammalian Circadian Clock von To, Tsz-Leung, Henson, Michael A., Herzog, Erik D., Doyle, Francis J.

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Effectors Enabling Adaptation to Mitochondrial Complex I Loss in Hürthle Cell Carcinoma von Gopal, Raj K, Vantaku, Venkata R, Panda, Apekshya, Reimer, Bryn, Rath, Sneha, To, Tsz-Leung, Fisch, Adam S, Cetinbas, Murat, Livneh, Maia, Calcaterra, Michael J, Gigliotti, Benjamin J, Pierce, Kerry A, Clish, Clary B, Dias-Santagata, Dora, Sadow, Peter M, Wirth, Lori J, Daniels, Gilbert H, Sadreyev, Ruslan I, Calvo, Sarah E, Parangi, Sareh, Mootha, Vamsi K

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