Azithromycin Inhibits Constitutive Airway Epithelial Sodium Channel Activation in Vitro and Modulates Downstream Pathogenesis in Vivo von Fujikawa, Haruka, Kawakami, Taise, Nakashima, Ryunosuke, Nasu, Aoi, Kamei, Shunsuke, Nohara, Hirofumi, Eto, Yuka, Ueno-Shuto, Keiko, Takeo, Toru, Nakagata, Naomi, Suico, Mary Ann, Kai, Hirofumi, Shuto, Tsuyoshi

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Metformin suppresses epithelial sodium channel hyperactivation and its associated phenotypes in a mouse model of obstructive lung diseases von Nakashima, Ryunosuke, Nohara, Hirofumi, Takahashi, Noriki, Nasu, Aoi, Hayashi, Megumi, Kishimoto, Tomoki, Kamei, Shunsuke, Fujikawa, Haruka, Maruta, Kasumi, Kawakami, Taisei, Eto, Yuka, Ueno-Shuto, Keiko, Suico, Mary Ann, Kai, Hirofumi, Shuto, Tsuyoshi

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A Splice Switch in SIGIRR Causes a Defect of IL-37-Dependent Anti-Inflammatory Activity in Cystic Fibrosis Airway Epithelial Cells von Ueno-Shuto, Keiko, Kamei, Shunsuke, Hayashi, Megumi, Fukuyama, Ayami, Uchida, Yuji, Tokutomi, Naofumi, Suico, Mary Ann, Kai, Hirofumi, Shuto, Tsuyoshi

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A cell-based high-throughput screening method to directly examine transthyretin amyloid fibril formation at neutral pH von Ueda, Mitsuharu, Okada, Masamitsu, Mizuguchi, Mineyuki, Kluve-Beckerman, Barbara, Kanenawa, Kyosuke, Isoguchi, Aito, Misumi, Yohei, Tasaki, Masayoshi, Ueda, Akihiko, Kanai, Akinori, Sasaki, Ryoko, Masuda, Teruaki, Inoue, Yasuteru, Nomura, Toshiya, Shinriki, Satoru, Shuto, Tsuyoshi, Kai, Hirofumi, Yamashita, Taro, Matsui, Hirotaka, Benson, Merrill D., Ando, Yukio

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Combinatorial screening for therapeutics in ATTRv amyloidosis identifies naphthoquinone analogues as TTR-selective amyloid disruptors von Sasaki, Ryoko, Suico, Mary Ann, Chosa, Keisuke, Teranishi, Yuriko, Sato, Takashi, Kagami, Asuka, Kotani, Shunsuke, Kato, Hikaru, Hitora, Yuki, Tsukamoto, Sachiko, Yamashita, Tomohiro, Yokoyama, Takeshi, Mizuguchi, Mineyuki, Kai, Hirofumi, Shuto, Tsuyoshi

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Intrapopulation analysis of longitudinal lifespan in Caenorhabditis elegans identifies W09D10.4 as a novel AMPK-associated healthspan shortening factor von Nakano, Yoshio, Moriuchi, Masataka, Fukushima, Yutaro, Hayashi, Kyotaro, Suico, Mary Ann, Kai, Hirofumi, Koutaki, Go, Shuto, Tsuyoshi

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Hydrogen bonds connecting the N-terminal region and the DE loop stabilize the monomeric structure of transthyretin von Inada, Yuki, Ono, Yuichiro, Okazaki, Kyo, Yamashita, Takuma, Kawaguchi, Tomoyuki, Kawano, Shingo, Kobashigawa, Yoshihiro, Shinya, Shoko, Kojima, Chojiro, Shuto, Tsuyoshi, Kai, Hirofumi, Morioka, Hiroshi, Sato, Takashi

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Combined effects of cisplatin and photon or proton irradiation in cultured cells: radiosensitization, patterns of cell death and cell cycle distribution von Iwata, Hiromitsu, Shuto, Tsuyoshi, Kamei, Shunsuke, Omachi, Kohei, Moriuchi, Masataka, Omachi, Chihiro, Toshito, Toshiyuki, Hashimoto, Shingo, Nakajima, Koichiro, Sugie, Chikao, Ogino, Hiroyuki, Kai, Hirofumi, Shibamoto, Yuta

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Nitric oxide facilitates the targeting Kupffer cells of a nano-antioxidant for the treatment of NASH von Maeda, Hitoshi, Ishima, Yu, Saruwatari, Junji, Mizuta, Yuki, Minayoshi, Yuki, Ichimizu, Shota, Yanagisawa, Hiroki, Nagasaki, Taisei, Yasuda, Kengo, Oshiro, Shun, Taura, Manabu, McConnell, Matthew J., Oniki, Kentaro, Sonoda, Kayoko, Wakayama, Tomohiko, Kinoshita, Manabu, Shuto, Tsuyoshi, Kai, Hirofumi, Tanaka, Motohiko, Sasaki, Yutaka, Iwakiri, Yasuko, Otagiri, Masaki, Watanabe, Hiroshi, Maruyama, Toru

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Melinjo seed extract increases adiponectin multimerization in physiological and pathological conditions von Oniki, Kentaro, Kawakami, Taisei, Nakashima, Azusa, Miyata, Keishi, Watanabe, Takehisa, Fujikawa, Haruka, Nakashima, Ryunosuke, Nasu, Aoi, Eto, Yuka, Takahashi, Noriki, Nohara, Hirofumi, Suico, Mary Ann, Kotani, Shunsuke, Obata, Yui, Sakamoto, Yuki, Seguchi, Yuri, Saruwatari, Junji, Imafuku, Tadashi, Watanabe, Hiroshi, Maruyama, Toru, Kai, Hirofumi, Shuto, Tsuyoshi

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TLR3 induction by anticancer drugs potentiates poly I:C‐induced tumor cell apoptosis von Taura, Manabu, Fukuda, Ryosuke, Suico, Mary Ann, Eguma, Ayaka, Koga, Tomoaki, Shuto, Tsuyoshi, Sato, Takashi, Morino‐Koga, Saori, Kai, Hirofumi

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A Split-Luciferase-Based Trimer Formation Assay as a High-throughput Screening Platform for Therapeutics in Alport Syndrome von Omachi, Kohei, Kamura, Misato, Teramoto, Keisuke, Kojima, Haruka, Yokota, Tsubasa, Kaseda, Shota, Kuwazuru, Jun, Fukuda, Ryosuke, Koyama, Kosuke, Matsuyama, Shingo, Motomura, Keishi, Shuto, Tsuyoshi, Suico, Mary Ann, Kai, Hirofumi

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Ergothioneine promotes longevity and healthy aging in male mice von Katsube, Makoto, Ishimoto, Takahiro, Fukushima, Yutaro, Kagami, Asuka, Shuto, Tsuyoshi, Kato, Yukio

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The ETS Factor Myeloid Elf-1-Like Factor (MEF)/Elf4 Is Transcriptionally and Functionally Activated by Hypoxia von Suico, Mary Ann, Taura, Manabu, Kudo, Eriko, Gotoh, Kumiko, Shuto, Tsuyoshi, Okada, Seiji, Kai, Hirofumi

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A novel condition of mild electrical stimulation exerts immunosuppression via hydrogen peroxide production that controls multiple signaling pathway von Piruzyan, Mariam, Shitanda, Ihori, Shimauchi, Yuichiro, Okita, Go, Tsurekawa, Yu, Moriuchi, Masataka, Nakano, Yoshio, Teramoto, Keisuke, Suico, Mary Ann, Shuto, Tsuyoshi, Kai, Hirofumi

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Evaluation of Three-Dimensional Cultured HepG2 Cells in a Nano Culture Plate System: an In Vitro Human Model of Acetaminophen Hepatotoxicity von Aritomi, Kohei, Ishitsuka, Yoichi, Tomishima, Yoshiro, Shimizu, Daisuke, Abe, Nazuki, Shuto, Tsuyoshi, Irikura, Mitsuru, Kai, Hirofumi, Irie, Tetsumi

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Lipopolysaccharide Decreases Single Immunoglobulin Interleukin-1 Receptor-related Molecule (SIGIRR) Expression by Suppressing Specificity Protein 1 (Sp1) via the Toll-like Receptor... von Ueno-Shuto, Keiko, Kato, Kosuke, Tasaki, Yukihiro, Sato, Miki, Sato, Keizo, Uchida, Yuji, Sakai, Hiromichi, Ono, Tomomi, Suico, Mary Ann, Mitsutake, Kazunori, Tokutomi, Naofumi, Kai, Hirofumi, Shuto, Tsuyoshi

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Mild electrical stimulation with heat shock attenuates renal pathology in adriamycin-induced nephrotic syndrome mouse model von Teramoto, Keisuke, Tsurekawa, Yu, Suico, Mary Ann, Kaseda, Shota, Omachi, Kohei, Yokota, Tsubasa, Kamura, Misato, Piruzyan, Mariam, Kondo, Tatsuya, Shuto, Tsuyoshi, Araki, Eiichi, Kai, Hirofumi

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STT3B-Dependent Posttranslational N-Glycosylation as a Surveillance System for Secretory Protein von Sato, Takashi, Sako, Yasuhiro, Sho, Misato, Momohara, Mamiko, Suico, Mary Ann, Shuto, Tsuyoshi, Nishitoh, Hideki, Okiyoneda, Tsukasa, Kokame, Koichi, Kaneko, Masayuki, Taura, Manabu, Miyata, Masanori, Chosa, Keisuke, Koga, Tomoaki, Morino-Koga, Saori, Wada, Ikuo, Kai, Hirofumi

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p53 Regulates Toll-Like Receptor 3 Expression and Function in Human Epithelial Cell Lines von Taura, Manabu, Eguma, Ayaka, Suico, Mary Ann, Shuto, Tsuyoshi, Koga, Tomoaki, Komatsu, Kensei, Komune, Takefumi, Sato, Takashi, Saya, Hideyuki, Li, Jian-Dong, Kai, Hirofumi

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