Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway von Fujino, Takeshi, Goyama, Susumu, Sugiura, Yuki, Inoue, Daichi, Asada, Shuhei, Yamasaki, Satoshi, Matsumoto, Akiko, Yamaguchi, Kiyoshi, Isobe, Yumiko, Tsuchiya, Akiho, Shikata, Shiori, Sato, Naru, Morinaga, Hironobu, Fukuyama, Tomofusa, Tanaka, Yosuke, Fukushima, Tsuyoshi, Takeda, Reina, Yamamoto, Keita, Honda, Hiroaki, Nishimura, Emi K., Furukawa, Yoichi, Shibata, Tatsuhiro, Abdel-Wahab, Omar, Suematsu, Makoto, Kitamura, Toshio

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Hepatocyte growth factor activator inhibitors (HAI‐1 and HAI‐2): Emerging key players in epithelial integrity and cancer von Kataoka, Hiroaki, Kawaguchi, Makiko, Fukushima, Tsuyoshi, Shimomura, Takeshi

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Possible role of combined therapy targeting MET and pro-HGF activation for renal cell carcinoma: analysis by human HGF-producing SCID mice von Fujii, Masato, Akioka, Takahiro, Kimura, Shoichi, Nagai, Takahiro, Kiwaki, Takumi, Fukushima, Tsuyoshi, Mukai, Shoichiro, Kamoto, Toshiyuki

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Eliminating chronic myeloid leukemia stem cells by IRAK1/4 inhibitors von Tanaka, Yosuke, Takeda, Reina, Fukushima, Tsuyoshi, Mikami, Keiko, Tsuchiya, Shun, Tamura, Moe, Adachi, Keito, Umemoto, Terumasa, Asada, Shuhei, Watanabe, Naoki, Morishita, Soji, Imai, Misa, Nagata, Masayoshi, Araki, Marito, Takizawa, Hitoshi, Fukuyama, Tomofusa, Lamagna, Chrystelle, Masuda, Esteban S., Ito, Ryoji, Goyama, Susumu, Komatsu, Norio, Takaku, Tomoiku, Kitamura, Toshio

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Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis von Asada, Shuhei, Goyama, Susumu, Inoue, Daichi, Shikata, Shiori, Takeda, Reina, Fukushima, Tsuyoshi, Yonezawa, Taishi, Fujino, Takeshi, Hayashi, Yasutaka, Kawabata, Kimihito Cojin, Fukuyama, Tomofusa, Tanaka, Yosuke, Yokoyama, Akihiko, Yamazaki, Satoshi, Kozuka-Hata, Hiroko, Oyama, Masaaki, Kojima, Shinya, Kawazu, Masahito, Mano, Hiroyuki, Kitamura, Toshio

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CRISPR/Cas9-mediated base-editing enables a chain reaction through sequential repair of sgRNA scaffold mutations von Fukushima, Tsuyoshi, Tanaka, Yosuke, Adachi, Keito, Masuyama, Nanami, Tsuchiya, Akiho, Asada, Shuhei, Ishiguro, Soh, Mori, Hideto, Seki, Motoaki, Yachie, Nozomu, Goyama, Susumu, Kitamura, Toshio

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Aberrant methylation and silencing of the SPINT2 gene in high‐grade gliomas von Fukushima, Tsuyoshi, Kawaguchi, Makiko, Yamamoto, Koji, Yamashita, Fumiki, Izumi, Aya, Kaieda, Takashi, Takezaki, Yuka, Itoh, Hiroshi, Takeshima, Hideo, Kataoka, Hiroaki

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Ghrelin administration suppresses inflammation‐associated colorectal carcinogenesis in mice von Kawaguchi, Makiko, Kanemaru, Ai, Fukushima, Tsuyoshi, Yamamoto, Koji, Tanaka, Hiroyuki, Haruyama, Yukihiro, Itoh, Hiroshi, Matsumoto, Nobuhiro, Kangawa, Kenji, Nakazato, Masamitsu, Kataoka, Hiroaki

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Protease‐activated receptor‐2 accelerates intestinal tumor formation through activation of nuclear factor‐κB signaling and tumor angiogenesis in ApcMin/+ mice von Kawaguchi, Makiko, Yamamoto, Koji, Kataoka, Hiroaki, Izumi, Aya, Yamashita, Fumiki, Kiwaki, Takumi, Nishida, Takahiro, Camerer, Eric, Fukushima, Tsuyoshi

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Role of the polycystic kidney disease domain in matriptase chaperone activity and localization of hepatocyte growth factor activator inhibitor‐1 von Yamashita, Fumiki, Kaieda, Takashi, Shimomura, Takeshi, Kawaguchi, Makiko, Lin, Chen‐Yong, Johnson, Michael D, Tanaka, Hiroyuki, Kiwaki, Takumi, Fukushima, Tsuyoshi, Kataoka, Hiroaki

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RELA fusion-positive ependymoma accompanied by extensive desmoplasia: a case report von Fukushima, Tsuyoshi, Ueda, Takashi, Hirato, Junko, Kataoka, Hiroaki

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Decreased prostasin expression is associated with aggressiveness of oral squamous cell carcinoma von Yamamoto, Koji, Yamashita, Fumiki, Kawaguchi, Makiko, Izumi, Aya, Kiwaki, Takumi, Kataoka, Hiroaki, Kaneuji, Takeshi, Yamashita, Yoshihiro, Fukushima, Tsuyoshi

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Meckel’s diverticulum with intraperitoneal hemorrhage in a child detected with screening laparoscopy: a case report von Wakizaka, Kazuki, Khor, Lee Wee, Annen, Kazuya, Fukushima, Tsuyoshi, Furuya, Mitsuko, Taketomi, Akinobu

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Anti-glioma Therapy with Temozolomide and Status of the DNA-Repair Gene MGMT von Fukushima, Tsuyoshi, Takeshima, Hideo, Kataoka, Hiroaki

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Supratentorial extra-axial RELA fusion-positive ependymoma misdiagnosed as meningioma by intraoperative histological and cytological examinations: a case report von Nagayasu, Mayumi Akaki, Fukushima, Tsuyoshi, Matsumoto, Fumitaka, Takeshima, Hideo, Sato, Yuichiro, Kataoka, Hiroaki

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Loss of hepatocyte growth factor activator inhibitor type 1 participates in metastatic spreading of human pancreatic cancer cells in a mouse orthotopic transplantation model von Ye, Jingjia, Kawaguchi, Makiko, Haruyama, Yukihiro, Kanemaru, Ai, Fukushima, Tsuyoshi, Yamamoto, Koji, Lin, Chen‐Yong, Kataoka, Hiroaki

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Insufficiency of hepatocyte growth factor activator inhibitor‐1 confers lymphatic invasion of tongue carcinoma cells von Izumi, Aya, Yamamoto, Koji, Kawaguchi, Makiko, Yamashita, Fumiki, Fukushima, Tsuyoshi, Kiwaki, Takumi, Tanaka, Hiroyuki, Yamashita, Yoshihiro, Kataoka, Hiroaki

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Congenital tracheo‐esophageal transition: A previously undescribed tracheo‐esophageal malformation that showed direct transition of the trachea to the esophagus von Kiwaki, Takumi, Nagayasu, Mayumi Akaki, Yamada, Naoshi, Kodama, Yuki, Umekita, Yoshiko, Fukushima, Tsuyoshi, Kataoka, Hiroaki, Tanaka, Hiroyuki

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Adrenomedullin alleviates mucosal injury in experimental colitis and increases claudin‐4 expression in the colonic epithelium von Kawaguchi, Makiko, Kataoka, Hiroaki, Kiwaki, Takumi, Weiting, Liang, Nagata, Sayaka, Kitamura, Kazuo, Fukushima, Tsuyoshi

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Hepatocyte Growth Factor Activator Inhibitor Type 1 Regulates Epithelial to Mesenchymal Transition through Membrane-Bound Serine Proteinases von HAIXIA CHENG, FUKUSHIMA, Tsuyoshi, TAKAHASHI, Nobuyasu, TANAKA, Hiroyuki, KATAOKA, Hiroaki

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