Peripheral Protein Quality Control as a Novel Drug Target for CFTR Stabilizer von Fukuda, Ryosuke, Okiyoneda, Tsukasa

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The COPD-Associated Polymorphism Impairs the CFTR Function to Suppress Excessive IL-8 Production upon Environmental Pathogen Exposure von Hinata, Daichi, Fukuda, Ryosuke, Okiyoneda, Tsukasa

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Mechanism-based corrector combination restores ΔF508-CFTR folding and function von Okiyoneda, Tsukasa, Veit, Guido, Dekkers, Johanna F, Bagdany, Miklos, Soya, Naoto, Xu, Haijin, Roldan, Ariel, Verkman, Alan S, Kurth, Mark, Simon, Agnes, Hegedus, Tamas, Beekman, Jeffrey M, Lukacs, Gergely L

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Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitylation as a Novel Pharmaceutical Target for Cystic Fibrosis von Fukuda, Ryosuke, Okiyoneda, Tsukasa

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Editorial: Advancing therapeutic strategies: exploring ABC transporters and chemicals affecting their expression and function for disease treatment von Veit, Guido, Matsuo, Michinori, Okiyoneda, Tsukasa

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Peripheral Protein Quality Control Removes Unfolded CFTR from the Plasma Membrane von Okiyoneda, Tsukasa, Barrière, Hervé, Bagdány, Miklós, Rabeh, Wael M, Du, Kai, Höhfeld, Jörg, Young, Jason C, Lukacs, Gergely L

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Efficient induction of proximity-dependent labelling by biotin feeding in BMAL1-BioID knock-in mice von Murata, Kazuya, Mimura, Asuka, Suzuki, Hayate, Mikami, Natsuki, Hamada, Yuko, Kato, Kanako, Iki, Natsumi, Ishida, Miyuki, Daitoku, Yoko, Tanimoto, Yoko, Okiyoneda, Tsukasa, Fujiyama, Tomoyuki, Dinh, Tra Thi Huong, Mizuno, Seiya, Sugiyama, Fumihiro

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Fixing cystic fibrosis by correcting CFTR domain assembly von Okiyoneda, Tsukasa, Lukacs, Gergely L

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Ligand-based virtual-screening identified a novel CFTR ligand which improves the defective cell surface expression of misfolded ABC transporters von Taniguchi, Shogo, Berenger, Francois, Doi, Yukako, Mimura, Ayana, Yamanishi, Yoshihiro, Okiyoneda, Tsukasa

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Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell von Bagdany, Miklos, Veit, Guido, Fukuda, Ryosuke, Avramescu, Radu G., Okiyoneda, Tsukasa, Baaklini, Imad, Singh, Jay, Sovak, Guy, Xu, Haijin, Apaja, Pirjo M., Sattin, Sara, Beitel, Lenore K., Roldan, Ariel, Colombo, Giorgio, Balch, William, Young, Jason C., Lukacs, Gergely L.

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The integral function of the endocytic recycling compartment is regulated by RFFL-mediated ubiquitylation of Rab11 effectors von Sakai, Ryohei, Fukuda, Ryosuke, Unida, Shin, Aki, Misaki, Ono, Yuji, Endo, Akinori, Kusumi, Satoshi, Koga, Daisuke, Fukushima, Toshiaki, Komada, Masayuki, Okiyoneda, Tsukasa

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Protein quality control at the plasma membrane von Okiyoneda, Tsukasa, Apaja, Pirjo M, Lukacs, Gergely L

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N-glycans are direct determinants of CFTR folding and stability in secretory and endocytic membrane traffic von Glozman, Rina, Okiyoneda, Tsukasa, Mulvihill, Cory M, Rini, James M, Barriere, Herve, Lukacs, Gergely L

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Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis von Balch, William E, Hutt, Darren M, Herman, David, Rodrigues, Ana P C, Noel, Sabrina, Pilewski, Joseph M, Matteson, Jeanne, Hoch, Ben, Kellner, Wendy, Kelly, Jeffery W, Schmidt, Andre, Thomas, Philip J, Matsumura, Yoshihiro, Skach, William R, Gentzsch, Martina, Riordan, John R, Sorscher, Eric J, Okiyoneda, Tsukasa, Yates, John R, Lukacs, Gergely L, Frizzell, Raymond A, Manning, Gerard, Gottesfeld, Joel M

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UBE3C Facilitates the ER-Associated and Peripheral Degradation of Misfolded CFTR von Kamada, Yuka, Tateishi, Hazuki, Nakayamada, Uta, Hinata, Daichi, Iwasaki, Ayuka, Zhu, Jingxin, Fukuda, Ryosuke, Okiyoneda, Tsukasa

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STT3B-Dependent Posttranslational N-Glycosylation as a Surveillance System for Secretory Protein von Sato, Takashi, Sako, Yasuhiro, Sho, Misato, Momohara, Mamiko, Suico, Mary Ann, Shuto, Tsuyoshi, Nishitoh, Hideki, Okiyoneda, Tsukasa, Kokame, Koichi, Kaneko, Masayuki, Taura, Manabu, Miyata, Masanori, Chosa, Keisuke, Koga, Tomoaki, Morino-Koga, Saori, Wada, Ikuo, Kai, Hirofumi

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The Ubiquitin Ligase RNF34 Participates in the Peripheral Quality Control of CFTR (RNF34 Role in CFTR PeriQC) von Taniguchi, Shogo, Ito, Yukiko, Kiritani, Hibiki, Maruo, Asuka, Sakai, Ryohei, Ono, Yuji, Fukuda, Ryosuke, Okiyoneda, Tsukasa

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ELISA Based Protein Ubiquitylation Measurement von Kamada, Yuka, Fukuda, Ryosuke, Okiyoneda, Tsukasa

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Revisiting the role of cystic fibrosis transmembrane conductance regulator and counterion permeability in the pH regulation of endocytic organelles von Barriere, Herve, Bagdany, Miklos, Bossard, Florian, Okiyoneda, Tsukasa, Wojewodka, Gabriella, Gruenert, Dieter, Radzioch, Danuta, Lukacs, Gergely L

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Enhanced CFTR modulator efficacy in ΔF508 CFTR mouse organoids by ablation of RFFL ubiquitin ligase von Hinata, Daichi, Fukuda, Ryosuke, Ishiguro, Hiroshi, Kamada, Yuka, Okiyoneda, Tsukasa

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