DYKAT of Baylis−Hillman Adducts:  Concise Total Synthesis of Furaquinocin E von Trost, Barry M, Thiel, Oliver R, Tsui, Hon-Chung

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Discovery of 3(S)-thiomethyl pyrrolidine ERK inhibitors for oncology von Boga, Sobhana Babu, Alhassan, Abdul-Basit, Cooper, Alan B., Doll, Ronald, Shih, Neng-Yang, Shipps, Gerald, Deng, Yongqi, Zhu, Hugh, Nan, Yang, Sun, Robert, Zhu, Liang, Desai, Jagdish, Patel, Mehul, Muppalla, Kiran, Gao, Xiaolei, Wang, James, Yao, Xin, Kelly, Joseph, Gudipati, Subrahmanyam, Paliwal, Sunil, Tsui, Hon-Chung, Wang, Tong, Sherborne, Bradley, Xiao, Li, Hruza, Alan, Buevich, Alexei, Zhang, Li-Kang, Hesk, David, Samatar, Ahmed A., Carr, Donna, Long, Brian, Black, Stuart, Dayananth, Priya, Windsor, William, Kirschmeier, Paul, Bishop, Robert

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MK-8353: Discovery of an Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology von Boga, Sobhana Babu, Deng, Yongqi, Zhu, Liang, Nan, Yang, Cooper, Alan B., Shipps, Gerald W., Doll, Ronald, Shih, Neng-Yang, Zhu, Hugh, Sun, Robert, Wang, Tong, Paliwal, Sunil, Tsui, Hon-Chung, Gao, Xiaolei, Yao, Xin, Desai, Jagdish, Wang, James, Alhassan, Abdul Basit, Kelly, Joseph, Patel, Mehul, Muppalla, Kiran, Gudipati, Subrahmanyam, Zhang, Li-Kang, Buevich, Alexei, Hesk, David, Carr, Donna, Dayananth, Priya, Black, Stuart, Mei, Hong, Cox, Kathleen, Sherborne, Bradley, Hruza, Alan W., Xiao, Li, Jin, Weihong, Long, Brian, Liu, Gongjie, Taylor, Stacey A., Kirschmeier, Paul, Windsor, William T., Bishop, Robert, Samatar, Ahmed A.

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Efforts towards the optimization of a bi-aryl class of potent IRAK4 inhibitors von Hanisak, Jennifer, Seganish, W. Michael, McElroy, William T., Tang, Haiquin, Zhang, Rui, Tsui, Hon-Chung, Fischmann, Theirry, Tulshian, Deen, Tata, James, Sondey, Christopher, Devito, Kristine, Fossetta, James, Garlisi, Charles G., Lundell, Daniel, Niu, Xiaoda

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Total Syntheses of Furaquinocin A, B, and E von Trost, Barry M, Thiel, Oliver R, Tsui, Hon-Chung

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Deracemization of Baylis−Hillman Adducts von Trost, Barry M, Tsui, Hon-Chung, Toste, F. Dean

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Enantiospecific Syntheses of (+)-Goniofufurone, (+)-7-epi-Goniofufurone, (+)-Goniobutenolide A, (-)-Goniobutenolide B, (+)-Goniopypyrone, (+)-Altholactone, (+)-Goniotriol, and (+)-... von Shing, Tony K. M, Tsui, Hon-Chung, Zhou, Zhao-Hui

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Discovery of a series of potent, orally active α,α-disubstituted piperidine NK1 antagonists von DONG XIAO, CHENG WANG, VARTY, Geoffrey, MORGAN, Cynthia, FEI LIU, NOMEIR, Amin, PALANI, Anandan, TSUI, Hon-Chung, REICHARD, Gregory, PALIWAL, Sunil, SHIH, Neng-Yang, ASLANIAN, Robert, DUFFY, Ruth, LACHOWICZ, Jean

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Cyclobutane derivatives as potent NK1 selective antagonists von WROBLESKI, Michelle Laci, REICHARD, Gregory A, PALIWAL, Sunil, SHAH, Sapna, TSUI, Hon-Chung, DUFFY, Ruth A, LACHOWICZ, Jean E, MORGAN, Cynthia A, VARTY, Geoffrey B, SHIH, Neng-Yang

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Stereochemical Models for the Enantiocontrolled Construction of Fully Functionalized C Rings via Intramolecular Aldolization in Advanced Precursors to Paclitaxel von Paquette, Leo A, Zeng, Qingbei, Tsui, Hon-Chung, Johnston, Jeffrey N

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Discovery of a novel, potent and orally active series of γ-lactams as selective NK1 antagonists von PALIWAL, Sunil, REICHARD, Gregory A, NOMEIR, Amin A, VARTY, Geoffrey B, SHIH, Neng-Yang, SHAH, Sapna, LACI WROBLESKI, Michelle, CHENG WANG, STENGONE, Carmine, TSUI, Hon-Chung, DONG XIAO, DUFFY, Ruth A, LACHOWICZ, Jean E

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Enantiospecific syntheses of (3 S,4 R)- and (3 S,4 R,7 S)-diastereoisomers of goniofufurone von Shing, Tony K.M., Tsui, Hon-Chung

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Reversible Charge-Accelerated Oxy-Cope Rearrangements von Tsui, Hon-Chung, Paquette, Leo A

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Stereocontrolled syntheses of (-)-goniofufurone and (-)-8-epi-goniofufurone von Shing, Tony K.M., Tsui, Hon-Chung, Zhou, Zhao-Hui

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Synthesis of Both Antipodal Forms of 7,7-Dimethylbicyclo[2.2.2]oct-2-en-5-one by Enantiomer Interconversion von Paquette, Leo A, Tsui, Hon-Chung

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Olefin Cleavage under Osmylation Conditions von Tsui, Hon-Chung, Paquette, Leo A

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Conformation of gem-disubstituted alkylarylpiperidines and their implication in design and synthesis of a conformationally-rigidified NK1 antagonist von Xiao, Dong, Wang, Cheng, Tsui, Hon-Chung, Palani, Anandan, Aslanian, Robert, Buevich, Alexei V.

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Application of an S → O Allylic Transposition in the Context of a Bridgehead Olefinic System. New Opportunities for the Structural Modification of Bicyclo[6.2.1]undecanes via Trans... von Johnston, Jeffrey N, Tsui, Hon-Chung, Paquette, Leo A

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Expedient Enantiocontrolled Synthesis of a Tetracyclic Lactone Structurally Related to the Kaurane Diterpenoids von Paquette, Leo A., Tsui, Hon-Chung

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Structure-based drug design of clinical compound MK-8353, a novel inhibitor of ERK von Hruza, Alan, Boga, Sobhana Babu, Alhassan, Abdul-Basit, Cooper, Alan B., Doll, Ronald, Shih, Neng-Yang, Shipps, Gerald, Deng, Yongqi, Zhu, Hugh, Nan, Yang, Sun, Robert, Zhu, Liang, Desai, Jagdish, Patel, Mehul, Muppalla, Kiran, Gao, Xiaolei, Wang, James, Kelly, Joseph, Gudipati, Subrahmanyam, Paliwal, Sunil, Tsui, Hon-Chung, Wang, Tong, Sherborne, Bradley, Xiao, Li, Buevich, Alexei, Hesk, David, Samatar, Ahmed A., Carr, Donna, Long, Brian, Black, Stuart, Dayananth, Priya, Windsor, William, Kirschmeier, Paul, Bishop, Robert

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